Patents by Inventor Andre Deflandre

Andre Deflandre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040136932
    Abstract: Topically applicable cosmetic/dermatological sunscreen compositions well suited for the UV-photoprotection of the skin and/or hair, contain (a) an effective UV-screening amount of at least one dibenzoylmethane compound and (b) an effective UV-photostabilizing amount of at least one 3-(2-azacycloalkylidene)-1,3-dihydroindol-2-one compound, formulated into (c) a topically applicable, cosmetically/dermatologically acceptable carrier therefor.
    Type: Application
    Filed: November 25, 2003
    Publication date: July 15, 2004
    Applicant: SOCIETE L'OREAL S.A.
    Inventors: Roger Rozot, Andre Deflandre
  • Patent number: 5670140
    Abstract: A photostable cosmetic filter composition for protecting human skin against UV radiation at wavelengths between 280 and 380 nm comprises, in a cosmetically acceptable support medium containing at least one oily phase, 1 to 3% by weight of a dibenzoylmethane derivative and at least 1% by weight of a substituted dialkylbenzalmalonate having formula I: ##STR1## R.sub.1 and R.sub.3 may be identical or different and represent H or a straight- or branched-chain C.sub.1 -C.sub.8 alkoxy radical.R.sub.2 and R.sub.4 represent a straight- or branched-chain C.sub.1 -C.sub.8 alkyl radical.The molar ratio of compound (I) to the dibenzoylmethane derivative is greater than or equal to 0.6.
    Type: Grant
    Filed: October 24, 1996
    Date of Patent: September 23, 1997
    Assignee: L'Oreal
    Inventors: Andre Deflandre, Serge Forestier, Gerard Lang, Herve Richard, Madeleine Leduc
  • Patent number: 5624663
    Abstract: A photostable cosmetic filter composition for protecting human skin against UV radiation at wavelengths between 280 and 380 nm comprises, in a cosmetically acceptable support medium containing at least one oily phase, 1 to 3% by weight of a dibenzoylmethane derivative and at least 1% by weight of a substituted dialkylbenzalmalonate having formula I: ##STR1## R.sub.1 and R.sub.3 may be identical or different and represent H or a straight- or branched-chain C.sub.1 -C.sub.8 alkoxy radical.R.sub.2 and R.sub.4 represent a straight- or branched-chain C.sub.1 -C.sub.8 alkyl radical.The molar ratio of compound (I) to the dibenzoylmethane derivative is greater than or equal to 0.6.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 29, 1997
    Assignee: L'Oreal
    Inventors: Andre Deflandre, Serge Forestier, Gerard Lang, Herve Richard, Madeleine Leduc
  • Patent number: 5618520
    Abstract: A photostable, filtering cosmetic composition for protecting human epidermis and hair against UV rays comprises, in a cosmetically acceptable carrier having at least one fatty phase 0.5 to 4% by weight of 4-(tert.-butyl) 4'-methoxy dibenzoylmethane and 0.1 to 20% by weight of a filtering polymer of the benzotriazole silicone type containing at least one unit of formula (1), where R' is a C.sub.1 -C.sub.30 hydrocarbon group, a C.sub.1 -C.sub.8 halogenated hydrocarbon group or a trimethylsilyloxy group; a is 1 or 2; X=--A--Y where A is an aliphatic or aromatic bivalent hydrocarbon radical having at least 2 carbon atoms and optionally containing one or more oxygen atoms; Y is a 2-(2'-hydroxyphenyl)benzotriazole residue optionally containing one or more C.sub.1 -C.sub.8 alkyl, C.sub.2 -C.sub.8 alkenyl, halogen, alkoxy, carboxy, hydroxy or amino substituents, the weight ratio of the benzotriazole silicone to the 4-(tert.-butyl) 4'-methoxy dibenzoylmethane being between 1 and 10.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: April 8, 1997
    Assignee: L'Oreal
    Inventors: Isabelle Hansenne, Serge Forestier, Andre Deflandre
  • Patent number: 5605680
    Abstract: The invention relates to a photostable screening cosmetic composition for protecting human skin against UV rays, comprising, in a cosmetically acceptable substrate containing at least one fatty phase, 1 to 3% by weight of 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane and at least 4.5% by weight of p-methylbenzylidenecamphor, the weight ratio of p-methylbenzylidenecamphor to 4-(1,1-dimethyl-ethyl)-4'-methoxydibenzoylmethane being higher than or equal to 3.It also relates to a process for protecting the skin against UV radiation and to a process for stabilizing 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane against UV radiation.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 25, 1997
    Assignee: L'Oreal
    Inventors: Andre Deflandre, Serge Forestier, Gerard Lang, Jean F. Grollier, Jean Cotteret
  • Patent number: 5587150
    Abstract: A photostable cosmetic screening composition and process for protection of the human epidermis against UV rays of wavelengths between 280 and 380 nm, the composition having, in a cosmetically acceptable vehicle containing at least one fatty phase, 1 to 5% by weight of a dibenzoylmethane derivative and at least 1% by weight of an alkyl .beta.-.beta.-diphenylacrylate or .alpha.-cyano-.beta.-.beta.-diphenylacrylate of formula (I), the mole ratio of the compound of formula (I) to the dibenzoylmethane derivative being not less than 0.8.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 24, 1996
    Assignee: L'Oreal
    Inventors: Andre Deflandre, Michel Dubois, Serge Forestier, Herve Richard
  • Patent number: 5576354
    Abstract: A photostable cosmetic screening composition and process for protection of the human epidermis against UV rays of wavelengths between 280 and 380 nm, the composition having, in a cosmetically acceptable vehicle containing at least one fatty phase, 1 to 5% by weight of a dibenzoylmethane derivative and at least 1% by weight of an alkyl .beta.-.beta.-diphenylacrylate or .alpha.-cyano-.beta.-.beta.-diphenylacrylate of formula (I), the mole ratio of the compound of formula (I) to the dibenzoylmethane derivative being not less than 0.8.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: November 19, 1996
    Assignee: L'Oreal
    Inventors: Andre Deflandre, Michel DuBois, Serge Forestier, Herve Richard
  • Patent number: 5567418
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: October 22, 1996
    Assignee: L'Oreal
    Inventors: Serge Forestier, Andre Deflandre
  • Patent number: 5538716
    Abstract: A photostable cosmetic composition for protecting the human epidermis against UV radiation comprises, in a cosmetically acceptable carrier, from 0.5 to 5% by weight of 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane and at least 0.5% by weight of a compound of formula (I): ##STR1## where R stands for an alkyl radical, the molar ratio of the compound of formula (I) to 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane being 0.8 or over.
    Type: Grant
    Filed: April 7, 1993
    Date of Patent: July 23, 1996
    Assignee: L'Oreal
    Inventors: Serge Forestier, Andre Deflandre
  • Patent number: 5223533
    Abstract: The invention relates to the benzylcyclanone derivatives of formula: ##STR1## where R.sub.1 and R.sub.3 denote H, OH, linear or branched C.sub.1 -C.sub.8 alkyl or linear or branched C.sub.1 -C.sub.8 alkoxy, R.sub.2 and R.sub.4 represent H or OH, at least one of the two being OH, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 represent H, C.sub.1 -C.sub.18 alkyl, aralkyl or aryl, it being possible for R.sub.5 and R.sub.6 and/or R.sub.7 and R.sub.8 to form an optionally substituted, saturated C.sub.5 -C.sub.12 ring, X represents O or --(CR.sub.9 R.sub.10).sub.n with n=1 or 2 and R.sub.9 and R.sub.10 represent H or CH.sub.3 ; if X represents --(CR.sub.9 R.sub.10).sub.n, R.sub.6 and R.sub.8, with the atoms of the ring to which they are attached, form a bicyclic system having 7 or 8 carbon atoms; if X represents --(CR.sub.9 R.sub.10).sub.n with n=1, R.sub.9 and R.sub.10 =CH.sub.3, R.sub.5 =H and R.sub.6 and R.sub.8, with the atoms of the ring to which are attached, form a bicyclic system having 7 carbon atoms, R.sub.
    Type: Grant
    Filed: March 29, 1990
    Date of Patent: June 29, 1993
    Assignee: L'Oreal
    Inventors: Serge Forestier, Alain LaGrange, Gerard Lang, Andre Deflandre, Bernadette Luppi
  • Patent number: 5178852
    Abstract: The invention relates to cosmetic and pharmaceutical compositions containing the derivatives of benzylidenecamphor of formula: ##STR1## where R.sub.1 denotes H, OH, C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.8 alkoxy, R.sub.3 denotes OH, C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.8 alkoxy, or else when R.sub.1 denotes H or OH, R.sub.3 can represent C.sub.1 -C.sub.8 alkyl, R.sub.2 and R.sub.4 denote H or OH, at least one of the radicals R.sub.2 and R.sub.4 representing OH.The compounds (I) are wide-band sunscreens and antioxidants, and are utilized in the treatment of cutaneous inflammations and allergies.
    Type: Grant
    Filed: March 29, 1990
    Date of Patent: January 12, 1993
    Assignee: L'Oreal
    Inventors: Serge Forestier, Alain Lagrange, Gerard Lang, Andre Deflandre, Bernadette Luppi
  • Patent number: 5158977
    Abstract: A 5,6,7,8-tetrahydro-1-naphthalenol derivative of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 represent lower alkyl,R.sub.5 and R.sub.6 represent hydrogen or lower alkyl,R represents hydrogen, C.sub.1 -C.sub.18 alkyl, C.sub.2 -C.sub.18 alkyl substituted by one or more hydroxyl groups, C.sub.3 -C.sub.18 alkenyl, C.sub.2 -C.sub.18 acyl, benzyl, benzoyl, carboxyl and carboxylic salts of an alkali or alkaline earth metal or of an organic amine.The derivative is useful as an antioxidant in cosmetic compositions and in pharmaceutical compositions for the preventive treatment of cutaneous inflammations and allergies or certain forms of cancer.
    Type: Grant
    Filed: June 7, 1991
    Date of Patent: October 27, 1992
    Assignee: L'Oreal
    Inventors: Jean Maignan, Gerard Malle, Andre Deflandre, Gerard Lang
  • Patent number: 5043482
    Abstract: A 5,6,7,8-tetrahydro-1-naphthalenol derivative of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 represent lower alkyl,R.sub.5 and R.sub.6 represent hydrogen or lower alkyl,R represents hydrogen, C.sub.1 -C.sub.18 alkyl, C.sub.2 -C.sub.18 alkyl substituted by one or more hydroxyl groups, C.sub.3 -C.sub.18 alkenyl, C.sub.2 -C.sub.18 acyl, benzyl, benzoyl, carboxyl and carboxylic salts of an alkali or alkaline earth metal or of an organic amine.The derivative is useful as an antioxidant in cosmetic compositions and in pharmaceutical compositions for the preventive treatment of cutaneous inflammations and allergies or certain forms of cancer.
    Type: Grant
    Filed: June 8, 1990
    Date of Patent: August 27, 1991
    Assignee: L'Oreal
    Inventors: Jean Maignan, Gerard Malle, Andre Deflandre, Gerard Lang
  • Patent number: 5000961
    Abstract: The invention relates to benzylidenecamphor derivatives of formula: ##STR1## where R is hydrogen or a tert-butyl residue, R.sub.1 is a C.sub.1 -C.sub.8 alkyl or alkoxy residue, and R.sub.2 and R.sub.3 denote hydrogen or hydroxyl, at least one of the two being hydroxyl, to a process for preparing them and to their uses as antioxidants, broad-band sunscreens and medicinal products for the preventive treatment of skin allergies and inflammations as well as for the prevention of certain cancers.
    Type: Grant
    Filed: May 23, 1990
    Date of Patent: March 19, 1991
    Assignee: L'Oreal
    Inventors: Gerard Lang, Serge Forestier, Alain Lagrange, Claudine Moire, Andre Deflandre
  • Patent number: 4994263
    Abstract: A composition for treatment and treatment of certain skin diseases is disclosed. The treatment combines furocoumarins, UV-A radiation, and a benzylidene-camphor derivative. The composition and treatment produces the desirable results of the furocoumarin/UV-A radiation treatment without the undesirable phototoxic side effects.
    Type: Grant
    Filed: April 30, 1990
    Date of Patent: February 19, 1991
    Assignee: L'Oreal
    Inventors: Gerard Lang, Andre Deflandre, Irena Beck
  • Patent number: 4952391
    Abstract: New tert-butyl derivatives of benzylidenecamphor, process for preparing them, their use as antioxidant agents and cosmetic and pharmaceutical compositions containing them.The invention relates to benzylidenecamphor derivatives of formula: ##STR1## where R is hydrogen or a tert-butyl residue, R.sub.1 is a C.sub.1 -C.sub.8 alkyl or alkoxy residue, and R.sub.2 and R.sub.3 denote hydrogen or hydroxyl, at least one of the two being hydroxyl, to a process for preparing them and to their uses as antioxidants, broad-band sunscreens and medicinal products for the preventive treatment of skin allergies and inflammations as well as for the prevention of certain cancers.
    Type: Grant
    Filed: October 5, 1988
    Date of Patent: August 28, 1990
    Assignee: L'Oreal
    Inventors: Gerard Lang, Serge Forestter, Alain LaGrange, Claudine Moire, Andre DeFlandre
  • Patent number: 4950478
    Abstract: The present invention relates to a cosmetic composition comprising a natural essence containing a phototoxic dose of furocoumarin, and 0.01 to 2% by weight of at least one benzylidenecamphor derivative filtering out UV-A radiation and chosen from among 3-p-oxybenzylidenebornan-2-ones, 3,3'-terephthalylidenedicamphors optionally sulfonated in the 10-position of the camphor, p-(3-methylidenecamphor)-cinnamic acid derivatives, 3,3'-terephthalylidenedicampho-10-sulfonamides or 3,3'-terephthalylidenedicampho-10,10'-disulfonamides.
    Type: Grant
    Filed: January 23, 1984
    Date of Patent: August 21, 1990
    Assignee: L'Oreal
    Inventors: Gerard Lang, Andre Deflandre, Irena Beck
  • Patent number: 4731200
    Abstract: The present invention relates to an alcoholic or aqueous-alcoholic composition comprising a natural essence containing a phototoxic dose of furocoumarin, and 0.01 to 2% by weight of at least one benzylidenecamphor derivative filtering out UV-A radiation and chosen from among 3-p-oxybenzylidenebornan-2-ones, 3,3'-terephthalylidenedicamphors optionally sulphonated in the 10-position of the camphor, p-(3-methylidenecamphor)cinnamic acid derivatives, 3,3'-terephthalylidenedicampho-10-sulphonamides or 3,3'-terephthalylidenedicampho-10,10'-disulphonamides.
    Type: Grant
    Filed: July 18, 1986
    Date of Patent: March 15, 1988
    Assignee: L'Oreal
    Inventors: Gerard Lang, Andre Deflandre, Irena Beck