Abstract: The invention relates to a method of measuring antigens or antibodies in biological fluids in appropriately designed reaction cells in an automated analytical apparatus. The method includes the steps of contacting, in the reaction cell, the biological fluid with antibodies specific for a desired analyte antigen, which antibodies are coated on magnetic particulate carrier, under conditions such that binding of the antibody to the desired analyte antigen occurs, and detecting the presence or absence of an immunocomplex formed between the antibody and the desired analyte antigen. The automated analytical apparatus includes a closed circuit transfer path having means for transferring cells around the entire transfer path, and a thermostating period for each analysis to be performed with the automated analytical apparatus. The transfer path includes a loading station, a reagent delivery station, a mixing and washing station, a separating station and a discharging station.

Abstract: The metering device for a slide analysis system deposits serum onto a slide that is held in a spotting position by a slide transfer device. The metering device is movable to a sampling position relative to a slide holding module to aspirate serum from a serum source on a slide cartridge in the slide holding module and is also movable to a spotting position to spot serum on the slide held by the slide transfer device. The metering device also has rotational as well as elevational movement and includes a built-in pipette tip ejector for discarding a used pipette tip.

Abstract: A guide rail or track system for guiding test tube holders or racks from one station to another, e.g., in a mono-channel analyzer, for presenting test tubes in such holders in sequence to one or more servicing operations at a plurality of stations. The rail system may comprise a main linear guide rail along which a holder having a row of test tubes supported therein is adapted to be moved longitudinally stepwise to present each test tube in the holder in sequence to a given station, or a given position therein, where an operation is to be carried out with respect to each test tube as it is presented in the station.