Patents by Inventor Andrea Choe

Andrea Choe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • UTILITY OF NEMATODE SMALL MOLECULES
    Publication number: 20240018177
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Application
    Filed: June 12, 2023
    Publication date: January 18, 2024
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. von Reuss
  • Utility of nematode small molecules
    Patent number: 11673908
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Grant
    Filed: August 1, 2022
    Date of Patent: June 13, 2023
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss
  • NEUROKININ ANTAGONISTS AND USES THEREOF
    Publication number: 20230128029
    Abstract: In some embodiments, methods of inhibiting, ameliorating, reducing the severity of, treating, reducing the likelihood of, or preventing social isolation stress or symptoms thereof in a subject in need thereof are described. In some embodiments, methods of determining a risk of social isolation stress in a subject are described.
    Type: Application
    Filed: September 30, 2022
    Publication date: April 27, 2023
    Inventors: David J. Anderson, Moriel Zelikowsky, Andrea Choe
  • ASCAROSIDE TREATMENT OF EOSINOPHILIC ESOPHAGITIS
    Publication number: 20230026686
    Abstract: A method of preventing or treating eosinophilic esophagitis (EoE) comprising administering a composition comprising ascr #7 is described.
    Type: Application
    Filed: September 9, 2022
    Publication date: January 26, 2023
    Inventors: Andrea CHOE, Paul W. Sternberg, Frank C. Schroeder
  • UTILITY OF NEMATODE SMALL MOLECULES
    Publication number: 20230024046
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Application
    Filed: August 1, 2022
    Publication date: January 26, 2023
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss
  • COMPOSITIONS AND METHODS FOR ASCAROSIDE MODIFICATION OF MAMMALIAN MICROBIOTA
    Publication number: 20220409650
    Abstract: Described herein are composition of ascarosides, methods of using them, and the like for inhibiting bacterial population growth or for altering the relative ratio of sub-populations of first and second bacteria in a mixed population of bacteria. The invention is particularly useful, for example, for modifying a microbiome of a patient (e.g., for treatment of gut microbiome dysfunction).
    Type: Application
    Filed: June 3, 2020
    Publication date: December 29, 2022
    Inventors: Andrea Choe, Brian Stoltz, Simon Bailey, Eduardo Martinez
  • Ascaroside treatment of eosinophilic esophagitis
    Patent number: 11464810
    Abstract: A method of preventing or treating eosinophilic esophagitis (EoE) comprising administering a composition comprising ascr#7 is described.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: October 11, 2022
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder
  • Neurokinin antagonists and uses thereof
    Patent number: 11458129
    Abstract: In some embodiments, methods of inhibiting, ameliorating, reducing the severity of, treating, reducing the likelihood of, or preventing social isolation stress or symptoms thereof in a subject in need thereof are described. In some embodiments, methods of determining a risk of social isolation stress in a subject are described.
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: October 4, 2022
    Assignee: California Institute of Technology
    Inventors: David J. Anderson, Moriel Zelikowsky, Andrea Choe
  • ASCAROSIDE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES
    Publication number: 20220016182
    Abstract: The present invention relates to the use of ascr#7 for preventing or treating IL-6 and/or IL-1?-mediated diseases.
    Type: Application
    Filed: July 30, 2021
    Publication date: January 20, 2022
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C, Schroeder
  • Ascaroside treatment of autoimmune and inflammatory diseases
    Patent number: 11077151
    Abstract: The present invention relates to the use of ascr #7 for preventing or treating IL-6 and/or IL-1?-mediated diseases.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: August 3, 2021
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder
  • UTILITY OF NEMATODE SMALL MOLECULES
    Publication number: 20200262856
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Application
    Filed: November 15, 2019
    Publication date: August 20, 2020
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss
  • Utility of nematode small molecules
    Patent number: 10479813
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: November 19, 2019
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss
  • ASCAROSIDE TREATMENT OF EOSINOPHILIC ESOPHAGITIS
    Publication number: 20190192578
    Abstract: A method of preventing or treating eosinophilic esophagitis (EoE) comprising administering a composition comprising ascr#7 is described.
    Type: Application
    Filed: August 25, 2017
    Publication date: June 27, 2019
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder
  • ASCAROSIDE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES
    Publication number: 20190175663
    Abstract: The present invention relates to the use of ascr#7 for preventing or treating IL-6 and/or IL-1?-mediated diseases.
    Type: Application
    Filed: August 25, 2017
    Publication date: June 13, 2019
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder
  • UTILITY OF NEMATODE SMALL MOLECULES
    Publication number: 20190153014
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Application
    Filed: January 18, 2019
    Publication date: May 23, 2019
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss
  • NEUROKININ ANTAGONISTS AND USES THEREOF
    Publication number: 20190125738
    Abstract: In some embodiments, methods of inhibiting, ameliorating, reducing the severity of, treating, reducing the likelihood of, or preventing social isolation stress or symptoms thereof in a subject in need thereof are described. In some embodiments, methods of determining a risk of social isolation stress in a subject are described.
    Type: Application
    Filed: November 1, 2018
    Publication date: May 2, 2019
    Inventors: David J. Anderson, Moriel Zelikowsky, Andrea Choe
  • Utility of nematode small molecules
    Patent number: 10183963
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: January 22, 2019
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss
  • UTILITY OF NEMATODE SMALL MOLECULES
    Publication number: 20180162893
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Application
    Filed: December 6, 2017
    Publication date: June 14, 2018
    Inventors: Andrea Choe, Paul W. Stemberg, Frank C. Schroeder, Stephen H. Von Reuss
  • Utility of nematode small molecules
    Patent number: 9868754
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: January 16, 2018
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss
  • Small molecule compounds that control plant- and insect-pathogenic nematodes
    Patent number: 9534008
    Abstract: The present invention relates to methods of modifying nematode behavior using certain isolated modulator compounds. Also disclosed are methods of promoting or inhibiting reproduction in a nematode population, methods of promoting or inhibiting nematode aggregation at a first location, and methods of treating or preventing parasite infection of a plant.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: January 3, 2017
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research, The United States of America, As Represented by the Secretary of Agriculture
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss, Fatma Kaplan, Peter A. Teal, Hans Alborn