Abstract: The present disclosure relates to a method and a system for biomechanically characterising ocular tissue (C) through deformation of the ocular tissue. The method comprises: generating an acoustic stimulus for delivery onto the ocular tissue in a collinear anner with an axis of a measuring device, for producing vibration of the ocular tissue; measuring ocular tissue displacement with the measuring device at a plurality of locations of the ocular tissue; obtaining at least a biomechanical parameter by processing the ocular tissue displacements at the plurality of locations. The disclosure also relates to a method and a system for screening biomechanical abnormality of ocular tissue (C).

Abstract: A system for obtaining biomechanical parameters of ocular tissue includes an air-puff module to deliver an air-puff stimulus onto the ocular tissue, and an imaging device operatively coupled to the air-puff module. The air-puff module includes a transparent window at its front with a transparent through hole for delivering the air-puff stimulus. The hole is aligned with an imaging device optical axis, such that the air-puff stimulus delivered onto the ocular tissue can be centred on an apex of the ocular tissue and made collinear with the optical axis. The transparent window and through hole allow continuity of imaging of the ocular surface. The imaging device captures the 3D coordinates of points distributed on an ocular tissue surface in groups of simultaneous points. The system includes a component for selecting and changing location and distribution of captured points on the ocular tissue, and a processing component to process the points.

Abstract: The present disclosure provides a method of volumetric imaging of a sample. The method comprises providing a plurality of depth images of a region of interest of the sample using a volumetric imaging system. The region of interest is below a surface area of interest of the sample. Each depth image is associated with a layer or slice of the region of interest and the plurality of depth images together forming a volumetric image of the region of interest. The method further comprises providing a surface image of the surface area of interest of the sample and identifying a surface image property of a surface feature of the surface area of interest. The method also comprises processing the plurality of depth images of the region of interest using the surface image property of the surface feature to improve a property of the depth images of the region of interest.

Abstract: The present disclosure provides a method of volumetric imaging of a sample. The method comprises providing a plurality of depth images of a region of interest of the sample using a volumetric imaging system. The region of interest is below a surface area of interest of the sample. Each depth image is associated with a layer or slice of the region of interest and the plurality of depth images together forming a volumetric image of the region of interest. The method further comprises providing a surface image of the surface area of interest of the sample and identifying a surface image property of a surface feature of the surface area of interest. The method also comprises processing the plurality of depth images of the region of interest using the surface image property of the surface feature to improve a property of the depth images of the region of interest.