Patents by Inventor Andrea Guerrini

Andrea Guerrini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticles as delivery vehicles of active ingredients and methods for the production thereof
    Patent number: 11344499
    Abstract: A nanoparticle comprising a keratin polypeptide and at least one lipophilic active ingredient, wherein the at least one lipophilic active ingredient is non-covalently bound to the keratin polypeptide and can be e.g. a therapeutic or diagnostic agent, a nutraceutical, a cosmetic ingredients, a dye or a cosmeceutical, the keratin polypeptide being water-soluble; optionally, the nanoparticle further comprises at least one hydrophilic active ingredient non-covalently bound to the keratin polypeptide, which can be e.g. a therapeutic or diagnostic agent, a nutraceutical, a cosmetic ingredients, a dye or a cosmeceutical.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: May 31, 2022
    Assignee: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Annalisa Aluigi, Greta Varchi, Giovanna Sotgiu, Andrea Guerrini, Marco Ballestri
  • NANOPARTICLES AS DELIVERY VEHICLES OF ACTIVE INGREDIENTS AND METHODS FOR THE PRODUCTION THEREOF
    Publication number: 20200206138
    Abstract: A nanoparticle comprising a keratin polypeptide and at least one lipophilic active ingredient, wherein the at least one lipophilic active ingredient is non-covalently bound to the keratin polypeptide and can be e.g. a therapeutic or diagnostic agent, a nutraceutical, a cosmetic ingredients, a dye or a cosmeceutical, the keratin polypeptide being water-soluble; optionally, the nanoparticle further comprises at least one hydrophilic active ingredient non-covalently bound to the keratin polypeptide, which can be e.g. a therapeutic or diagnostic agent, a nutraceutical, a cosmetic ingredients, a dye or a cosmeceutical.
    Type: Application
    Filed: June 13, 2018
    Publication date: July 2, 2020
    Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Annalisa ALUIGI, Greta VARCHI, Giovanna SOTGIU, Andrea GUERRINI, Marco BALLESTRI
  • Androgen receptor modulating compounds, preparation and uses thereof
    Patent number: 8859599
    Abstract: The present invention concerns compounds of general formula (I): Method of preparation and uses thereof.
    Type: Grant
    Filed: February 11, 2010
    Date of Patent: October 14, 2014
    Assignees: CNR—Consiglio Nazionale delle Ricerche, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.) S.r.l.
    Inventors: Greta Varchi, Andrea Guerrini, Anna Tesei, Giovanni Brigliadori
  • Non-steroidal compounds for androgen receptor modulation
    Patent number: 8741951
    Abstract: The present invention concerns compounds of general Formula (I): method of preparation and uses thereof.
    Type: Grant
    Filed: April 12, 2010
    Date of Patent: June 3, 2014
    Assignees: CNR—Consiglio Nazionale delle Ricerche, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.) S.r.l.
    Inventors: Greta Varchi, Andrea Guerrini, Anna Tesei, Giovanni Brigliadori
  • NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION
    Publication number: 20120041046
    Abstract: The present invention concerns compounds of general Formula (I): method of preparation and uses thereof.
    Type: Application
    Filed: April 12, 2010
    Publication date: February 16, 2012
    Applicant: CNR - CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Greta Varchi, Andrea Guerrini, Anna Tesei, Giovanni Brigliadori
  • Androgen receptor modulating compounds, preparation and uses thereof
    Publication number: 20110275829
    Abstract: The present invention concerns compounds of general formula (I): Method of preparation and uses thereof.
    Type: Application
    Filed: February 11, 2010
    Publication date: November 10, 2011
    Applicant: CNR - CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Greta Varchi, Andrea Guerrini, Anna Tesei, Giovanni Brigliadori
  • Taxane derivatives functionalized at the 14-position and a process for the preparation thereof
    Patent number: 7498452
    Abstract: A general process for the functionalization at the 14-position of 13-ketobaccatin derivatives of formula I to give derivatives of formula II wherein the substituents are as defined in the disclosure. The conversion of compounds of formula II in compounds of formula III, wherein the substituents are as defined in the disclosure, is also described.
    Type: Grant
    Filed: September 5, 2003
    Date of Patent: March 3, 2009
    Assignee: Indena S.p.A.
    Inventors: Gabriele Fontana, Ezio Bombardelli, Arturo Battaglia, Eleonora Baldelli, Andrea Guerrini, Maria Luisa Gelmi, Giacomo Carenzi, Donato Pocar
  • Process for the semisynthesis of deserpidine
    Patent number: 7468438
    Abstract: The present invention relates to an efficient procedure for the synthesis of deserpidine (Ia), starting from reserpic acid lactone (II) via the intermediate 11-O-demethyl reserpic acid lactone (III).
    Type: Grant
    Filed: March 2, 2005
    Date of Patent: December 23, 2008
    Assignee: Indena S.p.A.
    Inventors: Gabriele Fontana, Ezio Bombardelli, Cristian Samori, Eleonora Baldelli, Andrea Guerrini, Arturo Battaglia, Bruno Danieli
  • Process for the Semisynthesis of Deserpidine
    Publication number: 20080242864
    Abstract: The present invention relates to an efficient procedure for the synthesis of deserpidine (Ia), starting from reserpic acid lactone (II) via the intermediate 11-O-demethyl reserpic acid lactone (III).
    Type: Application
    Filed: March 2, 2005
    Publication date: October 2, 2008
    Inventors: Gabriele Fontana, Ezio Bombardelli, Cristian Samori, Eleonora Baldelli, Andrea Guerrini, Arturo Battaglia, Bruno Danieli
  • Process for the preparation of the 14?-hydroxy-baccatin III-1,14-carbonate
    Patent number: 7317113
    Abstract: A process for the preparation of 14?-hydroxy-baccatin III-1,14-carbonate useful for the preparation of novel taxane derivatives with antitumor activity.
    Type: Grant
    Filed: July 15, 2002
    Date of Patent: January 8, 2008
    Assignee: Indena S.p.A.
    Inventors: Ezio Bombardelli, Gabriele Fontana, Arturo Battaglia, Andrea Guerrini, Eleonora Baldelli
  • Taxane derivatives functionalized at the 14-position and a process for the preparation thereof
    Publication number: 20060122258
    Abstract: A general process for the functionalization at the 14-position of 13-ketobaccatin derivatives of formula I to give derivatives of formula II wherein the substituents are as defined in the disclosure. The conversion of compounds of formula II in compounds of formula III, wherein the substituents are as defined in the disclosure, is also described.
    Type: Application
    Filed: September 5, 2003
    Publication date: June 8, 2006
    Inventors: Gabriele Fontana, Ezio Bombardelli, Arturo Battaglia, Eleonora Baldelli, Andrea Guerrini, Maria Gelmi, Giacomo Carenzi, Donato Pocar
  • Process for the preparation of the 14beta-hydroxy-baccatin III-1, 14-carbonate
    Publication number: 20050020669
    Abstract: A process for the preparation of 14?-hydroxy-baccatin III-1,14-carbonate useful for the preparation of novel taxane derivatives with antitumor activity.
    Type: Application
    Filed: July 15, 2002
    Publication date: January 27, 2005
    Inventors: Ezio Bombardelli, Gabriele Battaglia, Andrea Guerrini
  • Process for the preparation of paclitaxel
    Patent number: 6768012
    Abstract: A process for the preparation of paclitaxel starting from 10-deacetylbaccatine III.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: July 27, 2004
    Assignee: Indena S.p.A.
    Inventors: Arturo Battaglia, Paolo Dambruoso, Andrea Guerrini, Ezio Bombardelli, Alessandro Pontiroli
  • Process for the preparation of paclitaxel
    Publication number: 20040049060
    Abstract: A process for the preparation of paclitaxel starting from 10-deacetylbaccatine III.
    Type: Application
    Filed: June 5, 2003
    Publication date: March 11, 2004
    Inventors: Arturo Battaglia, Paolo Dambruoso, Andrea Guerrini, Ezio Bombardelli, Alessandro Pontiroli