Patents by Inventor Andrea M. Femino

Andrea M. Femino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Single molecule detection by in situ hybridization
    Patent number: 5866331
    Abstract: Disclosed are methods for accurately determining the total emission intensity of a single fluorochrome, under imaging conditions, using a digital imaging fluorescence microscopy system. Also disclosed are methods for detecting and localizing probe-target molecule binding. The detection method has sufficient resolution and sensitivity to locate and detect a single target-bound probe.
    Type: Grant
    Filed: October 20, 1995
    Date of Patent: February 2, 1999
    Assignee: University of Massachusetts
    Inventors: Robert H. Singer, Andrea M. Femino