Patents by Inventor Andrea Nicoli
Andrea Nicoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10399724Abstract: A packaging machine may be provided for producing packages from a packaging material advanced along an advancing path. The packaging material may have a longitudinal edge arranged along the advancing path and a mark configured to provide an indication about the position of the packaging material. The packaging machine may include a forming unit configured to fold the packaging material into a tube having a longitudinal axis arranged along the advancing path, a first sensor configured to detect the position of the edge and generate a first control signal, a second sensor configured to read the mark and to generate a second signal, and a control device having an actuation device configured to move the packaging material in a direction arranged transversally with respect to the advancing path based on the first control signal and second signal. A method for producing packages from a packaging material may additionally be provided.Type: GrantFiled: March 24, 2016Date of Patent: September 3, 2019Assignee: TETRA LAVAL HOLDINGS & FINANCE S.A.Inventors: Vincenzo Aiello, Andrea Nicoli, Giuseppe Vandelli
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Publication number: 20180057199Abstract: The invention concerns a packaging machine for producing packages (2) from a packaging material (3) advanced along an advancing path (P), said packaging material having a longitudinal edge (53) arranged along said advancing path (P) and a mark (50) arranged for providing an indication about the position of said packaging material (3), said packaging machine comprising a forming unit for folding said packaging material (3) into a tube (9) having a longitudinal axis (A) arranged along said advancing path (P), a first sensor (52) arranged for detecting the position of said edge (53) and generating a first control signal (S1), a second sensor (54) arranged for reading said mark (50) and generating a second signal (S2), a control device (30) having a driving element (31, 47) arranged for moving said packaging material (3) in a transversal direction (T) arranged transversally with respect to said advancing path (P) on the basis said first control signal (S1) and said second signal (S2); the invention also concernsType: ApplicationFiled: March 24, 2016Publication date: March 1, 2018Inventors: Vincenzo Aiello, Andrea Nicoli, Giuseppe Vandelli
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Patent number: 8143443Abstract: A process for preparing gabapentin of formula 1, which comprises Formula (I) converting 1-allyl-cyclohexanecarboxaldehyde into 1-allyl-cyclohexanecarbonitrile; ozonizing 1-allyl-cyclohexanecarbonitrile to obtain 1-cyano-cyclohexaneacetaldehyde; acetalizing 1-cyano-cyclohexaneacetaldehyde with a suitable acetalizing agent to give the corresponding acetal and converting the latter into gabapentin.Type: GrantFiled: June 29, 2007Date of Patent: March 27, 2012Assignee: ZaCh System S.p.A.Inventors: Franco Ghelfi, Livius Cotarca, Fabrizio Roncaglia, Roberto Giovanetti, Andrea Nicoli
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Patent number: 8063041Abstract: The present disclosure relates to polymorphic Form D of bazedoxifene acetate, pharmaceutical compositions and methods of treatment using the same, and methods of preparing the same.Type: GrantFiled: June 22, 2010Date of Patent: November 22, 2011Assignee: Wyeth LLCInventors: Paolo Andreella, Roberto Brescello, Ivan Michieletto, Mauro Maffini, Nicola Catozzi, Andrea Nicoli, Paolo Fornasari, Massimo Verzini, Livius Cotarca, Franco Brazzarola
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Patent number: 7989658Abstract: The present invention relates to a process for the purification of gabapentin. The process relates to the addition of hydrochloric acid to an aqueous solution or suspension of gabapentin, before, during or after the concentration step of that solution, and the subsequent slurry of the gabapentin by the addition of an alcoholic solvent. The so obtained gabapentin has an high purity degree and, in particular, is characterized by a low content of lactam.Type: GrantFiled: December 15, 2005Date of Patent: August 2, 2011Assignee: ZaCh System S.p.A.Inventors: Roberto Giovanetti, Andrea Nicoli, Livius Cotarca
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Publication number: 20110021504Abstract: The present disclosure relates to polymorphic Form D of bazedoxifene acetate, pharmaceutical compositions and methods of treatment using the same, and methods of preparing the same.Type: ApplicationFiled: June 22, 2010Publication date: January 27, 2011Inventors: Paolo Andreella, Roberto Brescello, Ivan Michieletto, Mauro Maffini, Nicola Catozzi, Andrea Nicoli, Paolo Fornasari, Massimo Verzini, Livius Cotarca, Franco Brazzarola
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Publication number: 20100160436Abstract: Stable compositions containing gabapentin compositions, methods of preparing such compositions, and methods of using such compositions.Type: ApplicationFiled: March 1, 2010Publication date: June 24, 2010Applicant: ZaCh System S.p.A.Inventors: Vincenzo CANNATA, Francesco Corcella, Andrea Nicoli
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Publication number: 20100029983Abstract: A process for preparing gabapentin of formula 1, which comprises Formula (I) converting 1-allyl-cyclohexanecarboxaldehyde into 1-allyl-cyclohexanecarbonitrile; ozonizing 1-allyl-cyclohexanecarbonitrile to obtain 1-cyano-cyclohexaneacetaldehyde; acetalizing 1-cyano-cyclohexaneacetaldehyde with a suitable acetalizing agent to give the corresponding acetal and converting the latter into gabapentin.Type: ApplicationFiled: June 29, 2007Publication date: February 4, 2010Inventors: Franco Ghelfi, Livius Cotarca, Fabrizio Roncaglia, Roberto Giovanetti, Andrea Nicoli
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Publication number: 20090326266Abstract: A process for the preparation of 1,1-cyclohexanediacetic acid monoamide comprising the amination of 1,1-cyclohexanediacetic acid anhydride by reaction with aqueous NH3 at a temperature lower than 30° C. by using a NH3/anhydride molar ratio lower than 3, and the product precipitation through the acidification of the reaction mixture; a precipitation process of 1,1-cyclohexanediacetic acid monoamide; and a process for the synthesis of gabapentin comprising the above preparation of 1,1-cyclohexanediacetic acid monoamide, the Hofmann transposition of the same monoamide, the purification of a gabapentin salt and the crystallization from organic solvent.Type: ApplicationFiled: March 9, 2009Publication date: December 31, 2009Applicant: ZACH SYSTEM S.p.A.Inventors: Katiuscia ARRIGHI, Vincenzo CANNATA, Francesco CORCELLA, Gaetano MARCHIORO, Andrea NICOLI, Maurizio PAIOCCHI, Marco VILLA
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Publication number: 20090292138Abstract: The present invention relates to a process for the purification of gabapentin. The process relates to the addition of hydrochloric acid to an aqueous solution or suspension of gabapentin, before, during or after the concentration step of that solution, and the subsequent slurry of the gabapentin by the addition of an alcoholic solvent. The so obtained gabapentin has an high purity degree and, in particular, is characterized by a low content of lactam.Type: ApplicationFiled: December 15, 2005Publication date: November 26, 2009Applicant: ZACH SYSTEM S.P.A.Inventors: Roberto Giovanetti, Andrea Nicoli, Livius Cotarca
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Publication number: 20080300307Abstract: Stable compositions containing gabapentin compositions, methods of preparing such compositions, and methods of using such compositions.Type: ApplicationFiled: August 12, 2008Publication date: December 4, 2008Applicant: ZaCh System S.p.A.Inventors: Vincenzo Cannata, Francesco Corcella, Andrea Nicoli
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Patent number: 7417166Abstract: The present invention relates to a process for the preparation of gabapentin and, more particularly, it relates to a precipitation process of gabapentin by acidification of an aqueous solution deriving from the Hofmann rearrangement of 1,1-cyclohexanediacetic acid monoamide.Type: GrantFiled: March 21, 2005Date of Patent: August 26, 2008Assignee: Zach System S.p.A.Inventors: Roberto Giovanetti, Andrea Nicoli, Massimo Verzini, Giorgio Soriato, Livius Cotarca
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Patent number: 7393975Abstract: A process for the preparation of gabapentin which comprises the passage of a gabapentin inorganic salt through a strong cationic ionic exchange resin, the elution of gabapentin fixed on the column, the concentration of the resultant solution and the cristallization from organic solvent, characterized in that the elution of gabapentin fixed on the column is carried out by using an ammonia and alkaline hydroxide aqueous solution, is described.Type: GrantFiled: June 17, 2004Date of Patent: July 1, 2008Assignee: ZACH System S.p.A.Inventors: Livius Cotarca, Roberto Giovanetti, Andrea Nicoli
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Patent number: 7365227Abstract: A process for the purification of gabapentin by treatment of a crude aqueous gabapentin hydrochloride solution with a strong cationic ion exchange resin.Type: GrantFiled: March 28, 2006Date of Patent: April 29, 2008Assignee: ZACH System S.p.A.Inventors: Vincenzo Cannata, Andrea Nicoli, Francesco Corcella
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Patent number: 7365226Abstract: A process for the preparation of gabapentin comprising the passage of a salt of the same through a ionic exchange resin of strong cationic type, the elution of the gabapentin which has fixed onto the column and the crystallization from organic solvent, characterized in that the resin is regenerated by using a mineral acid in a molar quantity between 50 and 90%, is described.Type: GrantFiled: December 14, 2004Date of Patent: April 29, 2008Assignee: Zach System S.p.A.Inventors: Roberto Giovanetti, Andrea Nicoli, Angelo Restelli, Livius Cotarca
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Publication number: 20070293700Abstract: The present invention relates to a process for the preparation of gabapentin and, more particularly, it relates to a precipitation process of gabapentin by acidification of an aqueous solution deriving from the Hofmann rearrangement of 1,1-cyclohexanediacetic acid monoamide.Type: ApplicationFiled: March 21, 2005Publication date: December 20, 2007Applicant: Zambon Group S.P.A.Inventors: Roberto Giovanetti, Andrea Nicoli, Massimo Verzini, Giorgio Soriato, Livius Cotarca
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Publication number: 20070249718Abstract: Stable compositions containing gabapentin compositions, methods of preparing such compositions, and methods of using such compositions.Type: ApplicationFiled: July 9, 2007Publication date: October 25, 2007Applicant: ZaCH Systems S.p.A.Inventors: Vincenzo Cannata, Francesco Corcella, Andreas Nicoli
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Publication number: 20070129569Abstract: A process for the preparation of gabapentin which comprises the passage of a gabapentin inorganic salt through a strong cationic ionic exchange resin, the elution of gabapentin fixed on the column, the concentration of the resultant solution and the cristallization from organic solvent, characterized in that the elution of gabapentin fixed on the column is carried out by using an ammonia and alkaline hydroxide aqueous solution, is described.Type: ApplicationFiled: June 17, 2004Publication date: June 7, 2007Applicant: ZAMBON GROUP S.P.A.Inventors: Livius Cotarca, Roberto Giovanetti, Andrea Nicoli
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Publication number: 20070123590Abstract: A process for the preparation of gabapentin comprising the passage of a salt of the same through a ionic exchange resin of strong cationic type, the elution of the gabapentin which has fixed onto the column and the crystallization from organic solvent, characterized in that the resin is regenerated by using a mineral acid in a molar quantity between 50 and 90%, is described.Type: ApplicationFiled: December 14, 2004Publication date: May 31, 2007Applicant: Zambon Group S.P.A.Inventors: Roberto Giovanetti, Andrea Nicoli, Angelo Restelli, Livius Cotarca
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Patent number: 7199266Abstract: A process for the purification of gabapentin by treatment of a crude aqueous gabapentin hydrochloride solution with a strong cationic ion exchange resin.Type: GrantFiled: October 15, 2001Date of Patent: April 3, 2007Assignee: Zambon Group S.p.A.Inventors: Vincenzo Cannata, Andrea Nicoli, Francesco Corcella