Patents by Inventor Andrea Pavirani

Andrea Pavirani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Defective adenoviruses and corresponding complementation lines
    Patent number: 7067309
    Abstract: Novel defective adenoviruses for the transfer and expression of an exogenous nucleotide sequence in a host cell or organism. The invention also relates to novel complementation lines and to the process for the preparation of these novel defective adenoviruses and their use in therapy and to a pharmaceutical composition containing same.
    Type: Grant
    Filed: December 19, 2000
    Date of Patent: June 27, 2006
    Assignee: Transgene S.A.
    Inventors: Jean-Luc Imler, Majid Mehtali, Andréa Pavirani
  • Defective adenoviruses and corresponding complementation lines
    Patent number: 7005277
    Abstract: Novel defective adenoviruses for the transfer and expression of an exogenous nucleotide sequence in a host cell or organism. The invention also relates to novel complementation lines and to the process for the preparation of these novel defective adenoviruses and their use in therapy and to a pharmaceutical composition containing same.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: February 28, 2006
    Assignee: Transgene S.A.
    Inventors: Jean-Luc Imler, Majid Mehtali, Andréa Pavirani
  • Defective adenoviruses and corresponding complementation lines
    Publication number: 20030170885
    Abstract: Novel defective adenoviruses for the transfer and expression of an exogenous nucleotide sequence in a host cell or organism. The invention also relates to novel complementation lines and to the process for the preparation of these novel defective adenoviruses and their use in therapy and to a pharmaceutical composition containing same.
    Type: Application
    Filed: December 19, 2000
    Publication date: September 11, 2003
    Inventors: Jean-Luc Imler, Majid Mehtali, Andrea Pavirani
  • Adenovirus-mediated transfer of genes to the lung
    Publication number: 20020164304
    Abstract: The present invention relates, in general, to a adenovirus mediated transfer of genes to the lung. In particular, the present invention relates to a method of recombinant, replication-deficient adenovirus mediated transfer of desired genes to the lung whereby desired proteins of interest are produced for local and/or systemic use.
    Type: Application
    Filed: August 23, 2001
    Publication date: November 7, 2002
    Applicant: Transgene
    Inventors: Ronald G. Crystal, Wilfried Dalemans, Michel Perricaudet, Leslie Stratford-Perricaudet, Andrea Pavirani
  • Defective adenoviruses and corresponding complementation lines
    Publication number: 20010049136
    Abstract: Novel eective adenoviruses for the transfer and expression of an exogenous nucleotide sequence in a host cell or organism. The invention also relates to novel complementation lines and to the process for the preparation of these novel defective adenoviruses and their use in therapy and to a pharmaceutical composition containing same.
    Type: Application
    Filed: November 30, 2000
    Publication date: December 6, 2001
    Inventors: Jean-Luc Imler, Majid Mehtali, Andrea Pavirani
  • Replication deficient recombinant adenovirus vector
    Patent number: 6136594
    Abstract: The present invention relates to a replication deficient recombinant adenovirus vector in the genome of which is inserted an expression cassette comprising the DNA fragment coding for the human CFTR protein, said DNA fragment being placed under the control of the elements for the expression thereof.The present invention also concerns a vector according to claim 1 wherein in the expression cassette the human CFTR gene is under the control of the endogenous human CFTR promoter.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: October 24, 2000
    Assignee: Transgene S.A.
    Inventors: Wilfried Dalemans, Michel Perricaudet, Leslie Stratford-Perricaudet, Andrea Pavirani
  • Defective adenoviruses and corresponding complementation lines
    Patent number: 6133028
    Abstract: Novel defective adenoviruses for the transfer and expression of an exogenous nucleotide sequence in a host cell or organism. The invention also relates to novel complementation lines and to the process for the preparation of these novel defective adenoviruses and their use in therapy and to a pharmaceutical composition containing same.
    Type: Grant
    Filed: September 30, 1999
    Date of Patent: October 17, 2000
    Assignee: Transgene S.A.
    Inventors: Jean-Luc Imler, Majid Mehtali, Andrea Pavirani
  • Defective adenoviruses and corresponding complementation lines
    Patent number: 6040174
    Abstract: Novel defective adenoviruses for the transfer and expression of an exogenous nucleotide sequence in a host cell or organism. The invention also relates to novel complementation lines and to the process for the preparation of these novel defective adenoviruses and their use in therapy and to a pharmaceutical composition containing same.
    Type: Grant
    Filed: January 26, 1995
    Date of Patent: March 21, 2000
    Assignee: Transgene S.A.
    Inventors: Jean-Luc Imler, Majid Mehtali, Andrea Pavirani
  • Adenovirus comprising deletions on the E1A, E1B and E3 regions for transfer of genes to the lung
    Patent number: 6013638
    Abstract: The present invention relates, in general, to a adenovirus mediated transfer of genes to the lung. In particular, the present invention relates to a method of recombinant, replication-deficient adenovirus mediated transfer of desired genes to the lung whereby desired proteins of interest are produced for local and/or systemic use.
    Type: Grant
    Filed: December 13, 1993
    Date of Patent: January 11, 2000
    Assignees: The United States of America as represented by the Department of Health and Human Services, Transgene S.A.
    Inventors: Ronald G. Crystal, Wilfried Dalemans, Michel Perricaudet, Leslie Stratford-Perricaudet, Andrea Pavirani
  • Cell lines from a transgenic mouse which express biologically active IX factor
    Patent number: 5814716
    Abstract: Cell lines have been prepared from transgenic mice comprised of a first exogenous DNA sequence encoding human factor IX which is controlled by a promoter region specific for hepatic cells and a second exogenous DNA sequence encoding an oncogene, such as the SV40 virus gene encoding the T-antigen or the mouse c-myc gene, which is controlled by a promoter region specific for hepatic cells. Promoter regions specific for hepatic cells included the promoter region for the factor IX gene and the promoter region for the .alpha.-1 antitrypsin gene. The cultured cells produce biologically active human factor IX which is then isolated from the culture media.
    Type: Grant
    Filed: February 24, 1995
    Date of Patent: September 29, 1998
    Assignee: Transgene S.A.
    Inventors: Sophie Jallat, Pierre Meulien, Andrea Pavirani, Frederic Perraud
  • Factor VIII analog, preparation process, and pharmaceutical composition containing it
    Patent number: 5112950
    Abstract: Factor VIII analog which has undergone deletion of amino acids 771 to 1666, prepared from eukaryotic cells transformed by an expression vector carrying the cDNA of the factor VIII which has undergone deletion.
    Type: Grant
    Filed: June 26, 1991
    Date of Patent: May 12, 1992
    Assignee: Transgene S.A.
    Inventors: Pierre Meulien, Andrea Pavirani