Patents by Inventor Andrea S. Gobin
Andrea S. Gobin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240041907Abstract: Polymeric compositions are provided that include a poly(ethylene glycol), a viscoelastic polymer, and an antioxidant, where, in polymerized form, the compositions have a refractive index of about 1.30 to about 1.40. Methods of synthesizing the compositions are also provided and include the steps of heating an amount of water, adding a buffering agent to the water to form a buffer solution; mixing a poly(ethylene glycol) and a viscoelastic polymer into the buffer solution to form a reactive mixture; adding a plurality of antioxidant particles to the reactive mixture; and removing suspended gas bubbles from the reactive mixture. Methods of preventing oxidative damage to an eye lens of a subject are further provided and include administering the foregoing polymeric compositions to the eye lens of the subject.Type: ApplicationFiled: May 31, 2023Publication date: February 8, 2024Inventors: Tongalp H. Tezel, Andrea S. Gobin, Martin G. O'Toole
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Patent number: 11701375Abstract: Polymeric compositions are provided that include a poly(ethylene glycol), a viscoelastic polymer, and an antioxidant, where, in polymerized form, the compositions have a refractive index of about 1.30 to about 1.40. Methods of synthesizing the compositions are also provided and include the steps of heating an amount of water; adding a buffering agent to the water to form a buffer solution; mixing a poly(ethylene glycol) and a viscoelastic polymer into the buffer solution to form a reactive mixture; adding a plurality of antioxidant particles to the reactive mixture; and removing suspended gas bubbles from the reactive mixture. Methods of preventing oxidative damage to an eye lens of a subject are further provided and include administering the foregoing polymeric compositions to the eye lens of the subject.Type: GrantFiled: June 23, 2021Date of Patent: July 18, 2023Assignee: University of Louisville Research Foundation, Inc.Inventors: Tongalp H. Tezel, Andrea S. Gobin, Martin G. O'Toole
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Publication number: 20220110959Abstract: Polymeric compositions are provided that include a poly(ethylene glycol), a viscoelastic polymer, and an antioxidant, where, in polymerized form, the compositions have a refractive index of about 1.30 to about 1.40. Methods of synthesizing the compositions are also provided and include the steps of heating an amount of water; adding a buffering agent to the water to form a buffer solution; mixing a poly(ethylene glycol) and a viscoelastic polymer into the buffer solution to form a reactive mixture; adding a plurality of antioxidant particles to the reactive mixture; and removing suspended gas bubbles from the reactive mixture. Methods of preventing oxidative damage to an eye lens of a subject are further provided and include administering the foregoing polymeric compositions to the eye lens of the subject.Type: ApplicationFiled: June 23, 2021Publication date: April 14, 2022Inventors: Tongalp H. Tezel, Andrea S. Gobin, Martin G. O'Toole
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Publication number: 20190350956Abstract: Polymeric compositions are provided that include a poly(ethylene glycol), a viscoelastic polymer, and an antioxidant, where, in polymerized form, the compositions have a refractive index of about 1.30 to about 1.40. Methods of synthesizing the compositions are also provided and include the steps of heating an amount of water; adding a buffering agent to the water to form a buffer solution; mixing a poly(ethylene glycol) and a viscoelastic polymer into the buffer solution to form a reactive mixture; adding a plurality of antioxidant particles to the reactive mixture; and removing suspended gas bubbles from the reactive mixture. Methods of preventing oxidative damage to an eye lens of a subject are further provided and include administering the foregoing polymeric compositions to the eye lens of the subject.Type: ApplicationFiled: December 20, 2018Publication date: November 21, 2019Inventors: Tongalp H. Tezel, Andrea S. Gobin, Martin G. O'Toole
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Patent number: 10195225Abstract: Polymeric compositions are provided that include a poly(ethylene glycol), a viscoelastic polymer, and an antioxidant, where, in polymerized form, the compositions have a refractive index of about 1.30 to about 1.40. Methods of synthesizing the compositions are also provided and include the steps of heating an amount of water; adding a buffering agent to the water to form a buffer solution; mixing a poly(ethylene glycol) and a viscoelastic polymer into the buffer solution to form a reactive mixture; adding a plurality of antioxidant particles to the reactive mixture; and removing suspended gas bubbles from the reactive mixture. Methods of preventing oxidative damage to an eye lens of a subject are further provided and include administering the foregoing polymeric compositions to the eye lens of the subject.Type: GrantFiled: December 20, 2016Date of Patent: February 5, 2019Assignee: PromiSightInventors: Tongalp H. Tezel, Andrea S. Gobin, Martin G. O'Toole
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Publication number: 20180153917Abstract: Polymeric compositions are provided that include a poly(ethylene glycol), a viscoelastic polymer, and an antioxidant, where, in polymerized form, the compositions have a refractive index of about 1.30 to about 1.40. Methods of synthesizing the compositions are also provided and include the steps of heating an amount of water; adding a buffering agent to the water to form a buffer solution; mixing a poly(ethylene glycol) and a viscoelastic polymer into the buffer solution to form a reactive mixture; adding a plurality of antioxidant particles to the reactive mixture; and removing suspended gas bubbles from the reactive mixture. Methods of preventing oxidative damage to an eye lens of a subject are further provided and include administering the foregoing polymeric compositions to the eye lens of the subject.Type: ApplicationFiled: December 20, 2016Publication date: June 7, 2018Inventors: Tongalp H. Tezel, Andrea S. Gobin, Martin G. O'Toole
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Patent number: 9555054Abstract: Polymeric compositions are provided that include a poly(ethylene glycol), a viscoelastic polymer, and an antioxidant, where, in polymerized form, the compositions have a refractive index of about 1.30 to about 1.40. Methods of synthesizing the compositions are also provided and include the steps of heating an amount of water; adding a buffering agent to the water to form a buffer solution; mixing a poly(ethylene glycol) and a viscoelastic polymer into the buffer solution to form a reactive mixture; adding a plurality of antioxidant particles to the reactive mixture; and removing suspended gas bubbles from the reactive mixture. Methods of preventing oxidative damage to an eye lens of a subject are further provided and include administering the foregoing polymeric compositions to the eye lens of the subject.Type: GrantFiled: November 21, 2013Date of Patent: January 31, 2017Assignee: University of Louisville Research Foundation, Inc.Inventors: Tongalp H. Tezel, Andrea S. Gobin, Martin G. O'Toole
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Publication number: 20150290230Abstract: Polymeric compositions are provided that include a poly(ethylene glycol), a viscoelastic polymer, and an antioxidant, where, in polymerized form, the compositions have a refractive index of about 1.30 to about 1.40. Methods of synthesizing the compositions are also provided and include the steps of heating an amount of water; adding a buffering agent to the water to form a buffer solution; mixing a poly(ethylene glycol) and a viscoelastic polymer into the buffer solution to form a reactive mixture; adding a plurality of antioxidant particles to the reactive mixture; and removing suspended gas bubbles from the reactive mixture. Methods of preventing oxidative damage to an eye lens of a subject are further provided and include administering the foregoing polymeric compositions to the eye lens of the subject.Type: ApplicationFiled: November 21, 2013Publication date: October 15, 2015Inventors: Tongalp H. Tezel, Andrea S. Gobin, Martin G. O'Toole
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Patent number: 9061050Abstract: The invention provides hydrogels and methods for their use in treating disorders of the retina such as age-related macular degeneration (AMD).Type: GrantFiled: October 3, 2013Date of Patent: June 23, 2015Assignee: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.Inventors: Andrea S. Gobin, Tongalp H. Tezel
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Publication number: 20140121161Abstract: The invention provides hydrogels and methods for their use in treating disorders of the retina such as age-related macular degeneration (AMD).Type: ApplicationFiled: October 3, 2013Publication date: May 1, 2014Applicant: University of Louisville Research Foundation, Inc.Inventors: Andrea S. Gobin, Tongalp H. Tezel
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Publication number: 20130084262Abstract: The invention provides hydrogels and methods for their use in treating disorders of the retina such as age-related macular degeneration (AMD).Type: ApplicationFiled: April 19, 2011Publication date: April 4, 2013Inventors: Andrea S. Gobin, Tongalp H. Tezel
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Publication number: 20090162439Abstract: The present invention is directed to compositions and methods for preventing or inhibiting biofilm formation on a solid substrate comprising an antimicrobial agent and a biofilm-degrading enzyme embedded in a matrix material.Type: ApplicationFiled: December 22, 2008Publication date: June 25, 2009Applicant: University of Louisville Research FoundationInventor: Andrea S. Gobin