Abstract: The disclosure relates to a stent, in particular for treating carotid artery diseases, including a tubular braided mesh made of wires which are each helically wound about a longitudinal axis of the braided mesh and cross over and under one another. In an idle state, the braided mesh has a proximal cylindrical portion and a distal cylindrical portion which are connected to one another via a transition portion, wherein the proximal cylindrical portion has a different cross-sectional diameter and a different porosity compared to the distal cylindrical portion.

Abstract: The disclosure relates to a medical kit for treating vascular diseases, including a tubular or sleeve-type insertion aid, a transport wire having a distal tip, and a stent having a wire mesh which consists of a plurality of wires that, at a proximal stent end define loops and, at a distal stent end, open wire ends. The stent is arranged on the transport wire and together with the transport wire inside the insertion aid. The distal stent end is closer to the distal tip of the transport wire than the proximal stent end.

Abstract: Stent including a mesh of wires having a radiopaque core material and a superelastic shell material and defining loops at a first stent end and open wire ends at a second stent end. The number of wire ends is double the number of loops; and more than 10 vol. %, in particular more than 20 vol. %, more particularly at least 25 vol. %, in particular at least 30 vol. % of each wire is constituted by the core material. The mesh includes (i) 48 wires, each having a wire diameter of 0.038 mm and an outer diameter of 3.65 mm or 4.15 mm or 4.65 mm; (ii) 52 wires each having a wire diameter of 0.042 mm and an outer diameter of 5.17 mm or 5.67 mm or 6.17 mm; or (iii) 64 wires each having a wire diameter of 0.046 mm or 0.05 mm and an outer diameter of 7.18 mm or 8.20 mm.

Abstract: The disclosure relates to a system for braiding a patient-specific adapted stent. The system includes at least one set with multiple braiding sleeves and a base carrier for receiving at least two braiding sleeves of the set, wherein the braiding sleeves each have an inner contour adapted to the outer contour of the base carrier, so that multiple braiding sleeves can be arranged in any order on the base carrier, in particular slid in any order onto the base carrier, to form a braiding mandrel, and wherein at least two braiding sleeves of the set have different outer contours from each another. Furthermore, the invention relates to a method for braiding a patient-specific adapted stent.

Abstract: The invention relates to a stent having a tubular woven structure (3) formed from wire strands (1, 2) interwoven with one another, wherein at least one first wire strand (1) is formed by at least two individual wires (1.1, 1.2) which run adjacently and contact one another, wherein the first wire strand (1) winds helically in a first direction around an axis of rotation of the woven structure (3) and crosses at least one second wire strand (2), which comprises at least one individual wire (2.1) and winds helically in a second direction around the axis of rotation of the woven structure (3), and wherein at least one individual wire (1.1) of the first wire strand (1) comprises an X-ray visible core material which is encased by a sheath material having a lower X-ray visibility than the core material.

Abstract: Pyranoside derivatives of the formula I wherein 1, m and n independently of one another denote an integer chosen from 0, 1, 2, 3 and 4 and 1+m+n≦4. These are are LTB4-antagonists. Also disclosed are processes for making these compounds.

Abstract: The invention relates to new phenylamidine derivatives, processes for preparing them and their use as pharmaceutical compositions.