Patents by Inventor Andreas Emanuel Posch

Andreas Emanuel Posch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Single-molecule sequence and high sensitivity methylation analysis for tissue-specific analysis
    Patent number: 11920201
    Abstract: Provided herein are methods of determining one or more modification(s) of the nucleic acid sequence of at least one nucleic acid and at least one epigenetic alteration of the at least one nucleic acid in a sample of a subject. The sample is derived from a body fluid of the subject. The methods link the one or more modification(s) to a specific cell type.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: March 5, 2024
    Assignee: Siemens Healthcare GMBH
    Inventors: Carsten Dietrich, Andreas Emanuel Posch
  • Amplification-integrated genetic material depletion of non-target organisms using differentially abundant k-mers
    Patent number: 11572593
    Abstract: The present invention relates to a method of selectively amplifying at least one nucleic acid sequence of at least one microorganism and/or virus in a sample of a subject, wherein k-mers 3 are applied that show a difference in frequency and/or context in the genome 2 of the at least one microorganism and/or virus compared to the genome of the subject 1.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: February 7, 2023
    Assignee: Siemens Aktiengesellschaft
    Inventors: Carsten Dietrich, Yiwei Huang, Mark Matzas, Andreas Emanuel Posch
  • MOLECULAR PREDICTORS OF PATIENT RESPONSE TO RADIOTHERAPY TREATMENT
    Publication number: 20220275460
    Abstract: Disclosed are methods of predicting a radiotherapy success in a method of treating a lung cancer of a patient, the use of specific markers for predicting a radiotherapy success in a method of treating a lung cancer of a patient, a database comprising the markers, and a computer program product for use in such a method.
    Type: Application
    Filed: July 31, 2020
    Publication date: September 1, 2022
    Applicants: Siemens Healthcare GmbH, The Cleveland Clinic Foundation
    Inventors: Matthias SIEBERT, Carsten DIETRICH, Heike WEHNER, Jens-Christoph GEORGI, Mohamed ABAZEED, Andreas Emanuel POSCH, Andreas KAPPEL, Mark MATZAS
  • EPIGENOME-WIDE ASSOCIATION STUDY IDENTIFIES CARDIAC DEVELOPMENTAL GENE PATTERNING AND A NOVEL CLASS OF BIOMARKERS FOR HEART FAILURE
    Publication number: 20200181703
    Abstract: The present invention relates to a method of determining markers for a disease from a patient, wherein information from epigenomics and/or the transcriptome from peripheral blood and a diseased tissue or information from epigenomics and the transcriptome from peripheral blood or a diseased tissue is used for obtaining the markers, as well as a method of determining a risk for a disease in a patient using the markers obtained thereby.
    Type: Application
    Filed: July 6, 2017
    Publication date: June 11, 2020
    Applicant: Siemens Healthcare GmbH
    Inventors: Andreas Emanuel POSCH, Benjamin MEDER, Jan HAAS, Hugo A. KATUS, Maximilian WUERSTLE, Farbod SEDAGHAT-HAMEDANI, Andreas KELLER, Cord Friedrich STAEHLER
  • SINGLE-MOLECULE SEQUENCE AND HIGH SENSITIVITY METHYLATION ANALYSIS FOR TISSUE-SPECIFIC ANALYSIS
    Publication number: 20200002773
    Abstract: The present invention relates to methods of determining one or more modification(s) of the nucleic acid sequence of at least one nucleic acid and at least one epigenetic alteration of said at least one nucleic acid in a sample of a subject, wherein the sample is derived from a body fluid of the subject, in order to link the one or more modification to a specific cell type.
    Type: Application
    Filed: January 23, 2018
    Publication date: January 2, 2020
    Inventors: Carsten DIETRICH, Andreas Emanuel POSCH
  • AMPLIFICATION-INTEGRATED GENETIC MATERIAL DEPLETION OF NON-TARGET ORGANISMS USING DIFFERENTIALLY ABUNDANT K-MERS
    Publication number: 20190345569
    Abstract: The present invention relates to a method of selectively amplifying at least one nucleic acid sequence of at least one microorganism and/or virus in a sample of a subject, wherein k-mers 3 are applied that show a difference in frequency and/or context in the genome 2 of the at least one microorganism and/or virus compared to the genome of the subject 1.
    Type: Application
    Filed: November 28, 2017
    Publication date: November 14, 2019
    Inventors: Carsten Dietrich, Yiwei Huang, Mark Matzas, Andreas Emanuel Posch
  • STABLE PAN-GENOMES AND THEIR USE
    Publication number: 20190348154
    Abstract: The present invention relates to pan-genomes of bacterial species that are stable with regard to their core genome and the addition of new genes, their uses, as well as a data base containing these pan-genomes, a method of determining an antimicrobial drug profile using a pan-genome, a method of determining an infection of a patient and a method of selecting a treatment of a patient using a pan-genome, and a computer program product for carrying out the methods.
    Type: Application
    Filed: May 12, 2017
    Publication date: November 14, 2019
    Inventors: Patrick FRÖSE, Andreas Emanuel POSCH, Valentina GALATA, Andreas KELLER