Patents by Inventor Andreas H. M. De Vries

Andreas H. M. De Vries has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Boronic acid derivatives and synthesis thereof
    Patent number: 11286270
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, ?-lactamase inhibitors (BLIs).
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: March 29, 2022
    Assignee: Qpex Biopharma, Inc.
    Inventors: Scott J. Hecker, Serge Henri Boyer, Hubertus J. A. Dielemans, Angela Gonzalez de Castro, Andreas H. M. de Vries, Laurent Lefort
  • BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF
    Publication number: 20200407373
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, ?-lactamase inhibitors (BLIs).
    Type: Application
    Filed: October 10, 2018
    Publication date: December 31, 2020
    Inventors: Scott J. Hecker, Serge Henri Boyer, Hubertus J. A. Dielemans, Angela Gonzalez de Castro, Andreas H. M. de Vries, Laurent Lefort
  • Process for transition metal-catalyzed asymmetric hydrogenation of acrylic acid derivatives, and a novel catalyst system for asymmetric transition metal catalysis
    Patent number: 7473792
    Abstract: A process for transition metal-catalyzed, asymmetric hydrogenation of acrylic acid derivatives of the formula (I) in which R1 is H or an optionally substituted alkyl, aryl or heteroaryl radical, R2 is an optionally substituted alkyl, aryl or heteroaryl radical, and R3 is H or a C1-C6-alkyl radical, which comprises hydrogenating compounds of the formula (I), optionally in a solvent, in the presence of one or more hydrogen donors, using a catalyst system which comprises a transition metal from the group of ruthenium, rhodium and iridium and a combination of a chiral phosphorus ligand of the formula (II) in which Cn, together with the two oxygen atoms and the phosphorus atom, forms an optionally substituted ring having from 2 to 6 carbon atoms and R4 is an optionally substituted alkyl, aryl, alkoxy or aryloxy radical or NR5R6 where R5 and R6 may each independently be H or an optionally substituted alkyl, aryl, aralkyl or alkaryl radical, or, together with the nitrogen atom, may form a ring, and an achiral phosph
    Type: Grant
    Filed: December 5, 2005
    Date of Patent: January 6, 2009
    Assignee: DSM Fine Chemicals Austria Nfg GmbH & Co KG
    Inventors: Jeroen Boogers, Ulfried Felfer, Martina Kotthaus, Andreas H. M. De Vries, Johannes G. De Vries, Laurent Lefort, Gerhard Steinbauer
  • Process for Transition Metal-Catalyzed Asymmetric Hydrogenation of Acrylic Acid Derivatives, and a Novel Catalyst System for Asymmetric Transition Metal Catalysis
    Publication number: 20070293691
    Abstract: A process for transition metal-catalyzed, asymmetric hydrogenation of acrylic acid derivatives of the formula (I) in which R1 is H or an optionally substituted alkyl, aryl or heteroaryl radical, R2 is an optionally substituted alkyl, aryl or heteroaryl radical, and R3 is H or a C1-C6-alkyl radical, which comprises hydrogenating compounds of the formula (I), optionally in a solvent, in the presence of one or more hydrogen donors, using a catalyst system which comprises a transition metal from the group of ruthenium, rhodium and iridium and a combination of a chiral phosphorus ligand of the formula (II) in which Cn, together with the two oxygen atoms and the phosphorus atom, forms an optionally substituted ring having from 2 to 6 carbon atoms and R4 is an optionally substituted alkyl, aryl, alkoxy or aryloxy radical or NR5R6 where R5 and R6 may each independently be H or an optionally substituted alkyl, aryl, aralkyl or alkaryl radical, or, together with the nitrogen atom, may form a ring, and an achiral phosph
    Type: Application
    Filed: December 5, 2005
    Publication date: December 20, 2007
    Inventors: Jeroen Boogers, Ulfried Felfer, Martina Kotthaus, Andreas H.M. De Vries, Johannes De Vries, Laurent Lefort, Gerhard Steinbauer