Patents by Inventor Andreas Hoeft

Andreas Hoeft has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7291724
    Abstract: An oligonucoeotide selected from the group consisting of ISN2 (SEQ ID NO: 43), ISN2* (SEQ ID NO: 44), ISN (SEQ ID NO: 34), ISP2 (SEQ ID NO: 46), ISP2* (SEQ ID NO: 45) and ISP (SEQ ID NO: 33).
    Type: Grant
    Filed: November 2, 2006
    Date of Patent: November 6, 2007
    Assignee: Roche Diagnostics Corporation
    Inventors: Frank Stüber, Andreas Hoeft
  • Publication number: 20070042422
    Abstract: An oligonucoeotide selected from the group consisting of ISN2 (SEQ ID NO: 43), ISN2* (SEQ ID NO: 44), ISN (SEQ ID NO: 34), ISP2 (SEQ ID NO: 46), ISP2* (SEQ ID NO: 45) and ISP (SEQ ID NO: 33).
    Type: Application
    Filed: November 2, 2006
    Publication date: February 22, 2007
    Applicant: ROCHE DIAGNOSTICS CORPORATION
    Inventors: Frank Stuber, Andreas Hoeft
  • Patent number: 7169555
    Abstract: The invention relates to a method for quickly detecting bacterial DNA. The sample containing bacterial DNA is provided and treated according to a PCR method. The DNA copies which are multiplied by means of PCR are detected.
    Type: Grant
    Filed: December 27, 2000
    Date of Patent: January 30, 2007
    Assignee: Roche Diagnostics Corporation
    Inventors: Frank Stüber, Andreas Hoeft
  • Publication number: 20050079490
    Abstract: A method for identifying microbial DNA/RNA comprising providing a sample containing microbial DNA/RNA; enriching DNA/RNA in the sample by a PCR method wherein the DNA/RNA that is identified comprise copies which are amplified by the PCR method; preliminarily classifying at least one microorganism by identifying the microbial DNA/RNA by a melting curve; adding at least one labeled oligonucleotide whereby temperature-dependent hybridization takes place and identifying the DNA/RNA on the basis of a physical property of the resultant DNA/RNA oligonucleotide complex, such as the temperature-dependence of the hybridization.
    Type: Application
    Filed: December 27, 2000
    Publication date: April 14, 2005
    Applicant: Roche Diagnostics Corporation
    Inventors: Frank Stuber, Andreas Hoeft
  • Patent number: 6640129
    Abstract: A method and a device for determining liver function are described. Liver function is determined after injection of an indicator dye into the bloodstream, optical measurement of the resulting concentration of indicator dye in the bloodstream and calculation of a plasma elimination rate from the dye concentration-time curve of the indicator dye. An average circulation transit time mttcirc is calculated from the measurement of the dye concentration c(t). In addition, a parameter k representing a fractional reentry rate of the indicator dye after each pass through the circulation is determined. The plasma elimination rate PER is calculated according to the equation: PER=(1−k)/(k·mttcirc).
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: October 28, 2003
    Inventor: Andreas Hoeft
  • Patent number: 5865757
    Abstract: A process and a device for determining the cerebral blood flow, and the intracerebral blood volume are described.After injection into the bloodstream of a predefined quantity of a double indicator, arterial and venous measurements of the indicator dilution curves resulting in the blood stream are carried out. A dye solution differing in its temperature from the body temperature serves as a double indicator, in which heat or cold constitute a highly diffusible indicator component, and dye, preferably indo cyanine green ICG, constitute an intravascular indicator component. The cerebral blood flow CBF is calculated from the ratio of a distribution coefficient .lambda..sub.therm of the highly diffusible indicator component therm between blood and cerebral tissue and the mean transit time mtt.sub.therm of the highly diffusible indicator component therm through the brain. The intracerebral blood volume ICBV is calculated from the product of cerebral blood flow CBF and the mean transit time mtt.sub.
    Type: Grant
    Filed: May 29, 1997
    Date of Patent: February 2, 1999
    Inventor: Andreas Hoeft
  • Patent number: 5687726
    Abstract: A process of rapidly determining the blood circulation volume in a patient during surgery. Blood circulation volume is determined from circulation transport functions based on the evaluation of a compartmental analysis of a dye dilution curve. The information content of the entire dye dilution curve is utilized for the calculation of the parameters of the circulation transport function.
    Type: Grant
    Filed: April 3, 1995
    Date of Patent: November 18, 1997
    Inventor: Andreas Hoeft
  • Patent number: 5494031
    Abstract: An apparatus and method for measuring cardiac output in a patient, The sensed pulsatile component of light at at least two wavelengths transmitted through or reflected from a site on the patient is measured. The measurements are used to calculate the relative concentration of an indicator dye relative to a reference dye, the concentration of the latter being known. Calibrated absolute concentration time curves are then calculated for the indicator dye.
    Type: Grant
    Filed: February 28, 1994
    Date of Patent: February 27, 1996
    Inventor: Andreas Hoeft