Abstract: The present disclosure relates to a method of extracting circulating tumor cells (CTCs) from a blood sample from a human subject. This method includes adding a hyaluronan degrading enzyme to a blood sample from a subject in order to remove hyaluronan from the surface of the CTCs, bringing a CTC-capturing agent in contact with the CTCs and separating captured CTCs from the blood sample.

Abstract: A multi mode screen device for a vehicle, the device including a display screen unit with a display screen. The display screen unit is configured to switch an operational state between a first operational mode related to a manual vehicle driving functionality and a second operational mode related to an autonomous vehicle driving functionality. The display screen has a portrait orientation in the first operational mode and a landscape orientation in the second operational mode, and the display screen unit is adapted to be rotatably displaced between the portrait orientation and the landscape orientation.