Abstract: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa.

Abstract: A microplastic filter (also referred herein as fluid filter) for a washing machine has a filter housing, a first filter screen, a second filter screen, an inlet opening 16, and an outlet opening. The inlet and outlet openings communicate with each other through the first filter screen to define a direction of fluid flow. The first filter chamber has a retentate outlet, is particularly easy to handle if the second filter screen is arranged in a cavity of the filter housing, the inlet and outlet openings communicate with each other through the second filter screen, and the retentate outlet is arranged on a side of the second filter screen that faces the fluid flow.

Abstract: A method and device for controlled straightening and cooling of a wide metal strip, especially a steel strip or sheet metal, running out of a hot rolled strip rolling mill, using pinching rollers arranged in the moving direction of the strip behind vertical double rollers, said pinching rollers producing a tensile stress acting in a longitudinal direction. According to the invention, the range of use of conventional sheet metal cooling systems can be extended to obtain a more even surface of said steel strip with an increased cooling effect. This is achieved by displacing the metal strip or sheet metal between a pre-straightening machine and splash cooling facility in defined conditions of tensile stress by adjusting the tensile stress and by cooling said strip or sheet metal inside said splash cooling facility between successive pairs of pinching rollers and by additionally controlling the tensile stress.

Abstract: A method and device for controlled straightening and cooling of a wide metal strip, especially a steel strip (1) or sheet metal, running out of a hot rolled strip rolling mill, using pinching rollers (5) arranged in the moving direction of the strip (2) behind vertical double rollers (3,4), said pinching rollers producing a tensile stress (6) acting in a longitudinal direction. According to the invention, the range of use of conventional sheet metal cooling systems can be extended to obtain a more even surface of said steel strip (1) with an increased cooling effect. This is achieved by displacing the metal strip (1) or sheet metal between a pre-straightening machine (7) and splash cooling facility (8) in defined conditions of tensile stress (6) by adjusting the tensile stress (6) and by cooling said strip or sheet metal inside said splash cooling facility (8) between successive pairs (5a) of pinching rollers and by additionally controlling the tensile stress (6).