Abstract: A dental apparatus and method, for example an endodontic apparatus and method, is disclosed. The apparatus includes: a supply of fluid; a pump for delivering fluid from the supply under pressure and a handpiece in fluid communication with the pump. The handpiece includes a needle 30, extending from a rearward end proximal to the handpiece to a forward tip distal from the handpiece, a lumen of the needle extending to an opening at the tip to deliver fluid received from the pump to a tooth. The dimensions of the needle and the delivery pressure of the fluid are selected such that the flow of fluid through the needle causes a cloud of inertial cavitation to be formed forward of the needle tip.

Abstract: The present invention provides a polymerizable sanitizing formulation for forming a polymerized anti-microbial agent retaining material on a contact surface. The polymerizable sanitizing formulation comprising: a) a polymerizable water-soluble material; b) at least one initiator for radical polymerization of the polymerizable material to form a polymerized anti-microbial agent retaining material; c) at least one anti-microbial agent for retention within the polymerized anti-microbial agent retaining material; and d) at least one solvent.

Abstract: The invention relates to a highly flowable crosslinkable medical or dental composition comprising a crosslinkable compound, a polymerization initiator and a heterogeneous radiopacifier. Also described is a crosslinked polymer composition obtainable by crosslinking said highly flowable, crosslinkable medical or dental composition and the use of said highly flowable crosslinkable medical or dental composition to fill cavities or hollow structures in human or animal subjects.

Abstract: The invention relates to water soluble crosslinkable prepolymers for the preparation of chemically stable crosslinked polymer gels, a process for preparing the same, compositions containing the same and their use such as a medical or dental filler composition.

Abstract: A radiopaque composition with low viscosity and increased photopolymerizability for application or filling of hollow structures is disclosed. Moreover, a method to apply and monitor the application and/or the photopolymerization of the composition are presented.

Abstract: The present invention concerns an organic cavity injection device including an injection cannula for injecting a photo-activatable substance inside an organic cavity; at least one element or a plurality of elements configured to control the removal of a resident substance from the organic cavity and simultaneously prevent removal of the non-activated photo-activatable substance from the organic cavity; and an optical waveguide for providing electromagnetic radiation inside the organic cavity to the photo-activatable substance to photoactive the photo-activatable substance inside the organic cavity.

Abstract: A photopolymerizable bone filler material comprising a fluid polymeric material, a photoinitiator and a plurality of solid, polymeric optical fibers is disclosed, wherein said optical fibers are used for both illumination and reinforcement of the entire photopolymerized structure. In one embodiment, a mixture of PMMA and MMA is used as the fluid polymeric material. In one embodiment, the photoinitiator belongs to the bisacylphosphine oxide (BAPO) family, providing a complete, quick and reliable polymerization of a PMMA/MMA liquid bone cement upon application of a light of suitable wavelength. Contrary to other photoinitiators and chemically-similar compounds used in an experimental setting, the BAPO photoinitiator permits to obtain a polymerized bone cement which is mechanically robust and suitable for in vivo applications. Methods for using the developed fluid bone filler are also herein disclosed.

Abstract: A radiopaque composition with low viscosity and increased photopolymerizability for application or filling of hollow structures is disclosed. Moreover, a method to apply and monitor the application and/or the photopolymerization of the composition are presented.

Abstract: The present invention concerns an organic cavity injection device including an injection cannula for injecting a photo-activatable substance inside an organic cavity; at least one element or a plurality of elements configured to control the removal of a resident substance from the organic cavity and simultaneously prevent removal of the non-activated photo-activatable substance from the organic cavity; and an optical waveguide for providing electromagnetic radiation inside the organic cavity to the photo-activatable substance to photoactive the photo-activatable substance inside the organic cavity.

Abstract: The present invention relates to a device to photocure and/or photoactivate a photosensitive material. The device comprises several subsystems to transmit light towards an area of interest where a photosensitive material is applied as well as to collect light reflected by the applied photosensitive material. Reflected light is analyzed by an optical detector to monitor the photocuring and/or photoactivation process. Further means to inject or otherwise apply a photosensitive material can be combined in the same device. Methods for applying a fluent polymerizable material to a target site and for effecting polymerization of the fluent light-sensitive material in situ are also disclosed.