Abstract: The method relates to a press-hardened component with a tensile strength Rm>1600 MPa, in particular >1800 MPa, and especially >2000 MPa, wherein the component is manufactured from a steel material, wherein the steel material is a boron-manganese steel, which has a carbon content >0.30 mass %, wherein the steel material is hot rolled or hot rolled and cold rolled to a strip with a thickness of 0.5 to 3 mm, wherein the strip has a thin coating of zinc or a zinc-based alloy and a coating weight of <50 g/m2 on each strip side of the steel strip.

Abstract: The present invention relates to new extended release pharmaceutical compositions and methods of use thereof for the treatment of disorders.

Abstract: The present invention relates to new pharmaceutical compositions comprising benzoquinoline compounds, and methods to inhibit vesicular monoamine transporter 2 (VMAT2) activity in a subject for the treatment of chronic hyperkinetic movement disorders.

Abstract: The present invention relates to new benzoquinolone inhibitors of VMAT2, pharmaceutical compositions thereof, and methods of use thereof.

Abstract: The present invention relates to new extended release pharmaceutical compositions and methods of use thereof for the treatment of disorders.

Abstract: The present invention relates to new pharmaceutical compositions comprising benzoquinoline compounds, and methods to inhibit vesicular monoamine transporter 2 (VMAT2) activity in a subject for the treatment of chronic hyperkinetic movement disorders.

Abstract: The present invention relates to new extended release pharmaceutical compositions and methods of use thereof for the treatment of disorders.

Abstract: The invention relates to a method for press hardening sheet steel components in which a blank is detached from a sheet steel band composed of a hardenable steel alloy and the blank is then austenitized, in that it is heated to a temperature greater than Ac3 and is then inserted into a forming tool and formed in the forming tool, and during the forming, is cooled at a speed greater than the critical hardening speed, characterized in that in order to inhibit microcracks of the second type from being produced during the forming and hardening process in the sheet metal blanks that are to be formed, oxygen is supplied adjacent to the positive radii and/or drawing edges; the invention also relates to a device for performing this method.

Abstract: The present invention relates to new pharmaceutical compositions comprising benzoquinoline compounds, and methods to inhibit vesicular monoamine transporter 2 (VMAT2) activity in a subject for the treatment of chronic hyperkinetic movement disorders.

Abstract: A hygiene filter for a device for artificial respiration, having at least one filter for filtering microorganisms and/or solid particles from a respiratory air volume flow, and a device for artificial respiration, having a holding device within the air intake region. The filter material is designed as a seal against the respiratory air volume flow conducting elements such that the risk of the occurrence of secondary air is reduced.

Abstract: The present invention relates to new extended release pharmaceutical compositions and methods of use thereof for the treatment of disorders.

Abstract: The present invention relates to new pharmaceutical compositions comprising benzoquinoline compounds, and methods to inhibit vesicular monoamine transporter 2 (VMAT2) activity in a subject for the treatment of chronic hyperkinetic movement disorders.

Abstract: The present invention relates to new pharmaceutical compositions comprising benzoquinoline compounds, and methods to inhibit vesicular monoamine transporter 2 (VMAT2) activity in a subject for the treatment of chronic hyperkinetic movement disorders.

Abstract: The present invention relates to new benzoquinolone inhibitors of VMAT2, pharmaceutical compositions thereof, and methods of use thereof.

Abstract: The invention relates to a method for producing a hardened, steel component with regions of different hardness and/or ductility; a blank is stamped out and either heated in some regions to a temperature ?Ac3, and then transferred to a forming die, is formed, and is cooled at a speed that is greater than the critical hardening speed and thus hardened or is cold formed into the finished shape and the formed blank is heated in some regions to a temperature >Ac3 and then transferred to a hardening die and is hardened at a speed greater than the critical hardening speed; the steel material is adjusted in a transformation-delaying fashion so that a quench hardening through transformation of austenite into martensite takes place at a forming temperature that lies in the range from 450° C. to 700° C.; after the heating and before the forming, an active cooling takes place at >15 K/s.

Abstract: A method for heating a blank or a preformed steel sheet component for hot forming and/or quench hardening purposes. In at least some regions, the heating is carried out to a temperature above AC3; the heating of the blank is embodied as a rapid heating and to this end, the blank is heated in a first zone at an average heating rate of >25 K/s up to about 600° C. and above this temperature, is heated at an average heating rate of >10 K/s up to a maximum of the AC3 temperature and then is transferred to a second zone in which the blank that has been preheated in the first zone is heated in at least some regions to temperatures greater than AC3, in particular >850° C., with the heating rate in the second zone being >10 K/s. The invention also relates to a device for carrying out the method.

Abstract: A stator to guide a location-dependent magnetic field in a circumferential direction around a rotation axis. In one example, the stator includes a first stator ring revolving around the rotation axis, and a second stator ring revolving around the rotation axis and arranged concentrically with the first stator ring. The first and second stator rings include claws which are arranged so as to revolve around the rotation axis and at a distance from one another in the circumferential direction and engage with one another at least on a toothing axial plane. The claws are separated from one another by an air gap so that, when the magnetic field is arranged in the toothing axial plane, the magnetic field is guided towards the stator rings via the claws according to a relative angular position. Each claw has the contour of a mathematically smooth curve when viewed across the circumferential direction.

Abstract: The present invention relates to new extended release pharmaceutical compositions and methods of use thereof for the treatment of disorders.

Abstract: A method for producing partially hardened steel components in which a blank composed of a hardenable sheet steel is subjected to a temperature increase and shaped into a component; the component is transferred to a tool in which the heated component is cooled and thus quench hardened; during the heating of the blank or component in order to achieve the temperature increase to a temperature required for the hardening in regions that are to have a lower hardness and/or higher ductility, cooling elements are spaced apart from the surface by a small gap; the cooling element is dimensioned so that the thermal energy acting on the region that remains ductile flows through the component into the cooling element, characterized in that in order to space the cooling element apart from the component, micro-nubs or knobs are used, which are distributed over the area of the cooling element.

Abstract: The present invention relates to new extended release pharmaceutical compositions and methods of use thereof for the treatment of disorders.