Abstract: The present invention provides a controlled release formulation comprising a silicone substrate which comprises a compound of Formula (I): AA-AA-AA-X—Y. The invention further provides methods of making these formulations, medical devices such as dressings incorporating said formulations and medical uses thereof.

Abstract: The invention relates to an implantable valve (1) for a drainage system for discharging cerebrospinal fluid, comprising: a valve housing (10) extending along a valve axis (A), an inlet (2) and an outlet (3) as well as a valve housing (10) surrounding an interior space (4), a valve body assembly (600) arranged in the interior (4) and movably arranged in the interior space (4), a first valve seat (5), wherein the valve body assembly (600) is configured to abut the first valve seat (5) to close a flow connection between the inlet (2) and the interior space (4) of the valve housing (10), a second valve seat (7) which faces the first valve seat (5), wherein the valve body assembly (600) is configured to abut the second valve seat (7) to close a flow connection between the outlet (3) and the interior space (4) of the valve housing (10), and a spring device (800) arranged in the interior space (4) which exerts a spring force on the valve body assembly (600) in the direction of the first valve seat (5).

Abstract: A device for drainage includes a tubular reservoir having a tubular pliable wall, a rigid cover, and a rigid bottom, and also includes at least one spring which applies a force that presses the cover and the bottom apart, wherein the cover is movable in the direction of the bottom in order to place the spring into a start position. One or more magnets are configured such that the magnets apply an additional force on the reservoir in such a way that a resulting force pressing the cover and the bottom apart is substantially constant across as the spring is deflected.

Abstract: The invention relates to a device for determining a parameter for the diagnostics of hydrocephalus and other disorders of intracranial pressure, wherein information about the volume elasticity is obtained from a pressure signal or another characteristic signal which contains information about the pressure or the volume composition in the skull. The characteristic parameter determined according to the invention is the ratio of the amplitude of a modulating wave in the processed characteristic signal to the amplitude of the modulated wave in the course of the pulse amplitude of the modulated wave of the processed characteristic signal.

Abstract: A device for drainage includes a tubular reservoir having a tubular pliable wall, a rigid cover, and a rigid bottom, and also includes at least one spring which applies a force that presses the cover and the bottom apart, wherein the cover is movable in the direction of the bottom in order to place the spring into a start position. One or more magnets are configured such that the magnets apply an additional force on the reservoir in such a way that a resulting force pressing the cover and the bottom apart is substantially constant across as the spring is deflected.

Abstract: A suction and irrigation device for medical use comprises a valve body with an irrigation passage and a suction passage. At least one irrigation pipe and at least one suction pipe are connectable to the irrigation passage and the suction passage by connections at a proximal side of the valve body. A suction/irrigation tube is connectable to the irrigation passage and the suction passage at a distal side of the valve body by at least one further connection. A valve assembly is provided within the valve body, which in a first position opens the suction passage and closes the irrigation passage and in a second position closes the suction passage and opens the irrigation passage. The device comprises at least one push element which interacts with at least one movable element of the valve assembly, whereas the movable element is movable by mechanical force acted upon the push element such, that the push element activates the valve assembly from one position to the other position.

Abstract: The invention concerns an artificial heart driving device having at least one blood chamber which is disposed in a pump housing and draws in and expels blood cyclically by means of a plurality of pressure plates which can be driven by a motor. The motor is directly connected to a drive gear or cam component. A movement component actuating the plurality of pressure plates engages with the drive gear or cam component and performs a reciprocating movement as the drive gear or cam component rotates.