Abstract: Methods and systems for generating sterile slurry are provided. The slurry may be injected into subcutaneous fat of a subject to facilitate weight reduction or improve cosmetic appearances. Systems for generating a slurry comprise a repository for receiving a solution, a generator for generating the slurry from the solution, and a port for transferring the slurry from the system. Methods for generating a slurry comprise receiving a solution in a slurry generator, and generating slurry from the solution, wherein the slurry comprises ice particles capable of flowing through a cannula. Systems include continuous flow systems, agitated systems, and hybrid continuous flow and agitation systems.

Abstract: Systems and methods for generating slurry for injection are provided. Systems comprise a container and a device. The container comprises a solution for administration via an injection needle of a predetermined size. The device is capable of receiving the solution and producing a slurry having ice particles capable of flowing through the injection needle. Methods comprise selecting a container having the solution, receiving the solution in the device, and producing, in the device, the slurry having ice particles capable of flowing through the injection needle.