Patents by Inventor Andrew B. Herr

Andrew B. Herr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antimicrobial compositions of aminoglycosidic antibiotics and zinc ion chelators specifically formulated for enhanced inhibition of bacterial colonization and antibacterial efficacy
    Patent number: 10124064
    Abstract: Pharmaceutical compositions comprising an aminoglycosidic antibiotic and at least one zinc-chelating agent in a specified concentration, and methods of inhibiting bacterial colonization, biofilm formation and if treating bacterial infections utilizing the compositions are provided. Topical formulations suitable for wound care, and surface-applicable formulations suitable for medical, industrial and household disinfecting needs are also described.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: November 13, 2018
    Assignee: University of Cincinnati
    Inventors: Andrew B. Herr, Gary Young
  • Antimicrobial Compositions of Aminoglycosidic Antibiotics and Zinc Ion Chelators Specifically Formulated for Enhanced Inhibition of Bacterial Colonization and Antibacterial Efficacy
    Publication number: 20180036410
    Abstract: Pharmaceutical compositions comprising an aminoglycosidic antibiotic and at least one zinc-chelating agent in a specified concentration, and methods of inhibiting bacterial colonization, biofilm formation and if treating bacterial infections utilizing the compositions are provided. Topical formulations suitable for wound care, and surface-applicable formulations suitable for medical, industrial and household disinfecting needs are also described.
    Type: Application
    Filed: October 13, 2017
    Publication date: February 8, 2018
    Inventors: Andrew B. Herr, Gary Young
  • Antimicrobial compositions of aminoglycosidic antibiotics and zinc ion chelators specifically formulated for enhanced inhibition of bacterial colonization and antibacterial efficacy
    Patent number: 9821063
    Abstract: Pharmaceutical compositions comprising an aminoglycosidic antibiotic and at least one zinc-chelating agent in a specified concentration, and methods of inhibiting bacterial colonization, biofilm formation and if treating bacterial infections utilizing the compositions are provided. Topical formulations suitable for wound care, and surface-applicable formulations suitable for medical, industrial and household disinfecting needs are also described.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: November 21, 2017
    Assignee: University of Cincinnati
    Inventors: Andrew B. Herr, Gary Young
  • ANTIMICROBIAL COMPOSITIONS OF AMINOGLYCOSIDIC ANTIBIOTICS AND ZINC ION CHELATORS SPECIFICALLY FORMULATED FOR ENHANCED INHIBITION OF BACTERIAL COLONIZATION AND ANTIBACTERIAL EFFICACY
    Publication number: 20140308326
    Abstract: Pharmaceutical compositions comprising an aminoglycosidic antibiotic and at least one zinc-chelating agent in a specified concentration, and methods of inhibiting bacterial colonization, biofilm formation and if treating bacterial infections utilizing the compositions are provided. Topical formulations suitable for wound care, and surface-applicable formulations suitable for medical, industrial and household disinfecting needs are also described.
    Type: Application
    Filed: April 16, 2014
    Publication date: October 16, 2014
    Applicant: UNIVERSITY OF CINCINNATI
    Inventors: Andrew B. HERR, Stephan DAVIS, Gary YOUNG
  • Crystal of Human Glycoprotein VI Collagen Binding Domain
    Publication number: 20120135880
    Abstract: A crystal comprising the collagen binding domain of human GPVI is provided and defined by structural atomic coordinates. Employing computer modeling based on the crystal structure, including methods for identifying inhibitors of GPVI collagen binding activity, methods for screening libraries of compounds for potential to bind to the GPVI collagen binding domain, and methods of identifying a compound useful for the treatment of a GPVI-mediated disorder, are also provided.
    Type: Application
    Filed: November 28, 2011
    Publication date: May 31, 2012
    Inventors: Andrew B. Herr, Katsunori Horii
  • Crystal of human glycoprotein VI collagen binding domain
    Patent number: 8084577
    Abstract: A crystal comprising the collagen binding domain of human GPVI is provided and defined by structural atomic coordinates. Employing computer modeling based on the crystal structure, including methods for identifying inhibitors of GPVI collagen binding activity, methods for screening libraries of compounds for potential to bind to the GPVI collagen binding domain, and methods of identifying a compound useful for the treatment of a GPVI-mediated disorder, are also provided.
    Type: Grant
    Filed: March 28, 2007
    Date of Patent: December 27, 2011
    Assignee: University of Cincinnati
    Inventors: Andrew B. Herr, Katsunori Horii
  • USE OF ZINC CHELATORS TO INHIBIT BIOFILM FORMATION
    Publication number: 20110189260
    Abstract: A method is provided for inhibiting formation of a biofilm of bacteria, the method including contacting the bacteria with an effective amount of at least one zinc chelator, wherein the bacteria contain at least one zinc adhesion module, whereby formation of the biofilm is inhibited. A method for inhibiting biofilm formation on a device and a topical pharmaceutical composition for the inhibition of biofilm formation are also provided.
    Type: Application
    Filed: May 29, 2009
    Publication date: August 4, 2011
    Applicant: UNIVERSITY OF CINCINNATI
    Inventors: Andrew B. Herr, Deborah Gail Conrady, Cristin C. Brescia, Stefanie L. Ward
  • CRYSTAL STRUCTURE OF HUMAN GPVI AND APPLICATIONS THEREOF
    Publication number: 20100317536
    Abstract: A crystal comprising the collagen binding domain of human GPVI is provided and defined by structural atomic coordinates. Employing computer modeling based on the crystal structure, including methods for identifying inhibitors of GPVI collagen binding activity, methods for screening libraries of compounds for potential to bind to the GPVI collagen binding domain, and methods of identifying a compound useful for the treatment of a GPVI-mediated disorder, are also provided.
    Type: Application
    Filed: March 28, 2007
    Publication date: December 16, 2010
    Applicant: University of Cincinnati
    Inventors: Andrew B. Herr, Katsunori Horii