Patents by Inventor Andrew B. Kelson

Andrew B. Kelson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates
    Patent number: 7872134
    Abstract: 2-{[2-(Substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates and their salts, their preparation and intermediates in their preparation, pharmaceutical compositions containing them, and methods of treatment using them. The compounds are useful for treating cancer and autoimmune diseases, alone and in combination with other therapies.
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: January 18, 2011
    Assignee: Telik, Inc.
    Inventors: Edgardo Laborde, Andrew B. Kelson, Wenli Ma, Kevin T. Weber
  • 2-ethyl N,N-bis(2-chloroethyl)phosphorodiamidates
    Publication number: 20090156559
    Abstract: 2-{[2-(Substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates and their salts, their preparation and intermediates in their preparation, pharmaceutical compositions containing them, and methods of treatment using them. The compounds are useful for treating cancer and autoimmune diseases, alone and in combination with other therapies.
    Type: Application
    Filed: December 12, 2007
    Publication date: June 18, 2009
    Inventors: Edgardo Laborde, Andrew B. Kelson, Wenli Ma, Kevin T. Weber
  • Tripeptide and tetrapeptide thioethers
    Patent number: 7129215
    Abstract: Tripeptide and tetrapeptide thioethers, pharmaceutical compositions containing them, their pharmaceutical use, and their preparation. The compounds are useful in potentiating the cytotoxic effects of chemotherapeutic agents in tumor cells, selectively exerting toxicity in tumor cells, elevating the production of GM progenitors in bone marrow, stimulating the differentiation of bone marrow, mitigating the myelosuppressive effects of chemotherapeutic agents, and modulating hematopoiesis in bone marrow.
    Type: Grant
    Filed: January 4, 2006
    Date of Patent: October 31, 2006
    Assignee: Telik, Inc.
    Inventors: Natalia Aurrecoechea, Andrew B. Kelson, Robert W. Macsata, Louise Robinson, Anthony J. Sanchez, Nicholas M. Santiago, Steven R. Schow, Reyna J. Simon
  • Fluorinated 2-nitroimidazole analogs for detecting hypoxic tumor cells
    Patent number: 5721265
    Abstract: Agents useful for detecting hypoxic tumor cells are provided. The compounds have the structural formula (I) ##STR1## Methods of using the compounds to detect hypoxic tumor cells are also provided, as are pharmaceutical compositions formulated with the novel compounds.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: February 24, 1998
    Assignee: SRI International
    Inventors: Michael Tracy, Andrew B. Kelson, Paul Workman, Alexander D. Lewis, Eric O. Aboagye