Abstract: The invention provides methods of diagnosing neuropathic corneal pain by the detection of neuromas, such as micro-neuromas, on the cornea. The invention also features systems for detecting the presence of anatomical features located on an ocular tissue surface that may be a marker for neuropathic corneal pain. The systems feature an in vivo confocal microscope and a computer N programmed with a neural network to automate the analysis of the microscope images. The invention provides methods of using the system to identify a micro-neuroma in images collected of an ocular surface and methods of diagnosing neuropathic corneal pain and monitoring treatment of neuropathic corneal pain using a system of the invention.

Abstract: An automotive trim part is provided made of a laminated structure generally consisting of a thermoplastic core layer extruded from at least one feedstock derived from recycled material. The feedstock may consist at least partially of vehicle trim part waste from another vehicle, or trim part waste associated with an automotive trim part the same or similar to the part being produced. The core layer is preferably covered by fibrous layers and may be configured for use at least as a portion of a vehicle's wheel well.

Abstract: The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.

Abstract: A sun exposure sensor for disposable or single use including a substrate having an upper surface and a lower surface; a sun exposure sensing portion disposed on the upper surface of the substrate, the sun exposure sensing portion comprising a fluorescent toner image, wherein the fluorescent toner image increasingly fades upon exposure to sunlight; a sun exposure scale disposed on the upper surface of the substrate, the sun exposure scale comprising an evaluation image for evaluating an amount of fading of the fluorescent toner image; an optional coating layer disposed over all or a portion of the upper surface of the substrate; an optional backing layer disposed over all or a portion of the lower surface of the substrate. A process for preparing the sensor using xerographic toner printing.

Abstract: A sun exposure sensor for disposable or single use including a substrate having an upper surface and a lower surface; a sun exposure sensing portion disposed on the upper surface of the substrate, the sun exposure sensing portion comprising a fluorescent toner image, wherein the fluorescent toner image increasingly fades upon exposure to sunlight; a sun exposure scale disposed on the upper surface of the substrate, the sun exposure scale comprising an evaluation image for evaluating an amount of fading of the fluorescent toner image; an optional coating layer disposed over all or a portion of the upper surface of the substrate; an optional backing layer disposed over all or a portion of the lower surface of the substrate. A process for preparing the sensor using xerographic toner printing.

Abstract: The invention provides methods of diagnosing neuropathic corneal pain by the detection of neuromas, such as micro-neuromas, on the cornea. The invention also features systems for detecting the presence of anatomical features located on an ocular tissue surface that may be a marker for neuropathic corneal pain. The systems feature an in vivo confocal microscope and a computer N programmed with a neural network to automate the analysis of the microscope images. The invention provides methods of using the system to identify a micro-neuroma in images collected of an ocular surface and methods of diagnosing neuropathic corneal pain and monitoring treatment of neuropathic corneal pain using a system of the invention.