Patents by Inventor Andrew C. Lees

Andrew C. Lees has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240127451
    Abstract: Described herein are methods and computer systems for classification of CD8 T-cell topology using a patient response-based linear cutoff model. A plurality of histology images of tissue samples in a plurality of patients are received by a computer system. An image analysis of the plurality of histology images is performed to obtain a CD8+ T-cell abundance in the tumor parenchyma and stroma in each of the plurality of histology images. Real inflammation scores and tumor infiltration scores are determined based on a polar coordinate transformation of the CD8+ T-cell abundance in the tumor parenchyma and stroma. Based on the real inflammation scores and tumor infiltration scores, a feature space is generated, and linear boundaries or linear cutoffs between a plurality of classifications in the feature space are identified based on the real inflammation scores, the tumor infiltration scores, and patient response data.
    Type: Application
    Filed: February 25, 2022
    Publication date: April 18, 2024
    Applicant: Bristol-Myers Squibb Company
    Inventors: George C. Lee, Robin Edwards, Scott Ely, Daniel N. Cohen, John B. Wojcik, Vipul A. Baxi, Dimple Pandya, Jimena Trillo-Tinoco, Benjamin J. Chen, Andrew Fisher, Falon Gray
  • Patent number: 10914003
    Abstract: A gas delivery substrate for mounting gas supply components of a gas delivery system for a semiconductor processing apparatus is provided. The substrate may include a plurality of layers having major surfaces thereof bonded together forming a laminate with openings for receiving and mounting first, second, third and fourth gas supply components on an outer major surface. The substrate may include a first gas channel extending across an interior major surface that at least partially overlaps a second gas channel extending across a different interior major surface. The substrate may include a first gas conduit including the first gas channel connecting the first gas supply component to the second gas supply component, and a second gas conduit including the second channel connecting the third gas supply component to the fourth gas supply component. Also disclosed are various techniques for manufacturing gas delivery substrates.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: February 9, 2021
    Assignee: Lam Research Corporation
    Inventors: Andrew C. Lee, Michael C. Kellogg, Christopher J. Pena, John Edward Daugherty
  • Patent number: 10794519
    Abstract: Methods and apparatuses for additively manufactured tubular passages, additively manufactured manifolds, and additively manufactured heaters are provided.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: October 6, 2020
    Assignee: Lam Research Corporation
    Inventors: Christopher William Burkhart, Andrew C. Lee, David J. Hemker
  • Publication number: 20200141002
    Abstract: A gas delivery substrate for mounting gas supply components of a gas delivery system for a semiconductor processing apparatus is provided. The substrate may include a plurality of layers having major surfaces thereof bonded together forming a laminate with openings for receiving and mounting first, second, third and fourth gas supply components on an outer major surface. The substrate may include a first gas channel extending across an interior major surface that at least partially overlaps a second gas channel extending across a different interior major surface. The substrate may include a first gas conduit including the first gas channel connecting the first gas supply component to the second gas supply component, and a second gas conduit including the second channel connecting the third gas supply component to the fourth gas supply component. Also disclosed are various techniques for manufacturing gas delivery substrates.
    Type: Application
    Filed: December 23, 2019
    Publication date: May 7, 2020
    Inventors: Andrew C. Lee, Michael C. Kellogg, Christopher J. Pena, John Edward Daugherty
  • Patent number: 10557197
    Abstract: A gas delivery substrate for mounting gas supply components of a gas delivery system for a semiconductor processing apparatus is provided. The substrate may include a plurality of layers having major surfaces thereof bonded together forming a laminate with openings for receiving and mounting first, second, third and fourth gas supply components on an outer major surface. The substrate may include a first gas channel extending across an interior major surface that at least partially overlaps a second gas channel extending across a different interior major surface. The substrate may include a first gas conduit including the first gas channel connecting the first gas supply component to the second gas supply component, and a second gas conduit including the second channel connecting the third gas supply component to the fourth gas supply component. Also disclosed are various techniques for manufacturing gas delivery substrates.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: February 11, 2020
    Assignee: Lam Research Corporation
    Inventors: Andrew C. Lee, Michael C. Kellogg, Christopher J. Pena, John E. Daugherty
  • Publication number: 20190211955
    Abstract: Methods and apparatuses for additively manufactured tubular passages, additively manufactured manifolds, and additively manufactured heaters are provided.
    Type: Application
    Filed: January 7, 2019
    Publication date: July 11, 2019
    Inventors: Christopher William Burkhart, Andrew C. Lee, David J. Hemker
  • Patent number: 10215317
    Abstract: Methods and apparatuses for additively manufactured tubular passages, additively manufactured manifolds, and additively manufactured heaters are provided.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: February 26, 2019
    Assignee: Lam Research Corporation
    Inventors: Christopher William Burkhart, Andrew C. Lee, David J. Hemker
  • Patent number: 10118263
    Abstract: Component-locating templates or masks for use with positioning fluid-flow components on monolithic ceramic substrates are provided, as well as techniques for the manufacture of such templates.
    Type: Grant
    Filed: September 2, 2015
    Date of Patent: November 6, 2018
    Assignee: Lam Researech Corporation
    Inventors: Michael C. Kellogg, Andrew C. Lee, Christopher J. Pena
  • Patent number: 9879795
    Abstract: A manifold constructed by additive manufacturing for use in semiconductor processing tools is provided. The manifold may include a mixing chamber and portions of a plurality of flow paths with each flow path including a first fluid flow component interface, a second fluid flow component interface, a first tubular passage fluidically connecting the first mixing chamber with a first fluid flow component interface outlet of that flow path, and a second tubular passage fluidically connecting a first fluid flow component interface inlet of that flow path with a second fluid flow component interface outlet of that flow path. Each fluid flow component interface is configured to interface with a corresponding fluid flow component such that the corresponding fluid flow component, when installed, is able to interact with fluid flow between the fluid flow component interface inlet and the fluid flow component interface outlet.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: January 30, 2018
    Assignee: Lam Research Corporation
    Inventors: Christopher William Burkhart, Andrew C. Lee
  • Publication number: 20170203511
    Abstract: Methods and apparatuses for additively manufactured tubular passages, additively manufactured manifolds, and additively manufactured heaters are provided.
    Type: Application
    Filed: March 31, 2016
    Publication date: July 20, 2017
    Inventors: Christopher William Burkhart, Andrew C. Lee, David J. Hemker
  • Publication number: 20170204989
    Abstract: A manifold constructed by additive manufacturing for use in semiconductor processing tools is provided. The manifold may include a mixing chamber and portions of a plurality of flow paths with each flow path including a first fluid flow component interface, a second fluid flow component interface, a first tubular passage fluidically connecting the first mixing chamber with a first fluid flow component interface outlet of that flow path, and a second tubular passage fluidically connecting a first fluid flow component interface inlet of that flow path with a second fluid flow component interface outlet of that flow path. Each fluid flow component interface is configured to interface with a corresponding fluid flow component such that the corresponding fluid flow component, when installed, is able to interact with fluid flow between the fluid flow component interface inlet and the fluid flow component interface outlet.
    Type: Application
    Filed: January 15, 2016
    Publication date: July 20, 2017
    Inventors: Christopher William Burkhart, Andrew C. Lee
  • Publication number: 20170057028
    Abstract: Component-locating templates or masks for use with positioning fluid-flow components on monolithic ceramic substrates are provided, as well as techniques for the manufacture of such templates.
    Type: Application
    Filed: September 2, 2015
    Publication date: March 2, 2017
    Inventors: Michael C. Kellogg, Andrew C. Lee, Christopher J. Pena
  • Publication number: 20160108523
    Abstract: A gas delivery substrate for mounting gas supply components of a gas delivery system for a semiconductor processing apparatus is provided. The substrate may include a plurality of layers having major surfaces thereof bonded together forming a laminate with openings for receiving and mounting first, second, third and fourth gas supply components on an outer major surface. The substrate may include a first gas channel extending across an interior major surface that at least partially overlaps a second gas channel extending across a different interior major surface. The substrate may include a first gas conduit including the first gas channel connecting the first gas supply component to the second gas supply component, and a second gas conduit including the second channel connecting the third gas supply component to the fourth gas supply component. Also disclosed are various techniques for manufacturing gas delivery substrates.
    Type: Application
    Filed: October 15, 2015
    Publication date: April 21, 2016
    Inventors: Andrew C. Lee, Michael C. Kellogg, Christopher J. Pena, John E. Daugherty
  • Patent number: 8563183
    Abstract: An integrated dry gas fuel cell (IDG-FC) is provided. The IDG-FC includes at least one solid oxide fuel cell having an anode, a cathode and an electrolyte membrane disposed between the anode and the cathode. The IDG-FC further includes a conversion bed, where carbon dioxide gas is provided to the conversion bed to convert carbon monoxide gas from the carbon dioxide gas. Solid carbonaceous fuel is provided to the conversion bed to promote the gas conversion. The carbon monoxide is provided as fuel to the anode, and air is supplied to the cathode to provide oxygen for oxidation of the carbon monoxide at the anode to generate electric power. This new process does not require water, and supplies the oxygen required for the oxidation reaction through an ionically selective solid oxide electrolyte membrane.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: October 22, 2013
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Turgut M. Gür, Reginald E. Mitchell, Andrew C. Lee, Siwen Li
  • Publication number: 20100258691
    Abstract: A screen protector assembly for use with a flat panel display having a display panel located on a front surface thereof. The screen protector assembly comprises a transparent screen panel having a pair of slots formed therein adjacent a top edge of the screen panel and a pair of c-shaped hanger clamps for detachably securing the screen panel to the flat panel display. Each clamp hanger comprises a top portion for engaging a top surface of the flat panel display, an arm extending downwardly from the top portion, and a tail portion end for providing a clamping force between the screen panel and the back surface of the front panel display. The arm has a tab protruding rearwardly from the arm with an upwardly extending hook forming a neck for supporting a top surface of the slot. The tab is shaped to fit within the slot of the screen panel such that a top surface of the slot rests on the neck and hangs thereform.
    Type: Application
    Filed: April 9, 2010
    Publication date: October 14, 2010
    Inventors: James J. Zdancewicz, Dana C. Zdancewicz, Andrew R. Richards, Andrea N. Sweeney-Richards, Andrew C. Lees
  • Publication number: 20090004529
    Abstract: An integrated dry gas fuel cell (IDG-FC) is provided. The IDG-FC includes at least one solid oxide fuel cell having an anode, a cathode and an electrolyte membrane disposed between the anode and the cathode. The IDG-FC further includes a conversion bed, where carbon dioxide gas is provided to the conversion bed to convert carbon monoxide gas from the carbon dioxide gas. Solid carbonaceous fuel is provided to the conversion bed to promote the gas conversion. The carbon monoxide is provided as fuel to the anode, and air is supplied to the cathode to provide oxygen for oxidation of the carbon monoxide at the anode to generate electric power. This new process does not require water, and supplies the oxygen required for the oxidation reaction through an ionically selective solid oxide electrolyte membrane.
    Type: Application
    Filed: June 26, 2008
    Publication date: January 1, 2009
    Inventors: Turgut M. Gur, Reginald E. Mitchell, Andrew C. Lee, Siwen Li