Abstract: The system invention describes a support and improved method of application and removal. The support, comprised of a network of flexible, non-porous, multi-lumen tubing interlaces at a plurality of junctions to form a lattice structure. Apertures designed to accommodate boney prominences also permit air or water to reach the skin underneath and encourage rapid fluid flow internally through the lattice. A hydrophobic, thermal-resistant, flowable padding layer is injected within a secondary lumen to the lattice structure, spanning its complete surface area. As a result, the breathability of the support is not affected by this padding layer because it mirrors the apertures of the lattice. At least one liquid is injected into the structure and configured to transform into a solid when acted on by an external mechanical stimulus.

Abstract: The invention provides a p38 MAPK inhibitor of Formula I, or a pharmaceutically acceptable salt or solvate thereof: for use in the treatment or prevention of hypercytokinemia in a human patient; wherein R is C1-3alkyl, optionally substituted by one or more halo, NR1R2 or hydroxy, and R1and R2 are independently H, halo or C1-3alkyl, optionally substituted by one or more F. Also provided are compositions for use in the treatment or prevention of hypercytokinemia comprising the p38 MAPK inhibitor of Formula I; and methods for treating or preventing hypercytokinemia in a human patient in need thereof comprising administering to the patient a therapeutically or prophylactically effective amount of a p38 MAPK inhibitor of Formula I. The invention also provides a p38 MAPK inhibitor and an antimicrobial agent, such as an antiviral agent, for use in the treatment or prevention of hypercytokinemia.

Abstract: The subject invention pertains to medical apparatuses and methods for reducing or preventing leakage of injected therapeutic agents (including liquid-containing substances, cells) into a solid or hollow tissue/organ after puncturing.

Abstract: The subject invention pertains to medical apparatuses and methods for reducing or preventing leakage of injected therapeutic agents (including liquid-containing substances, cells) into a solid or hollow tissue/organ after puncturing.

Abstract: A temperature-controlled container includes a container having a temperature source incorporated into at least a portion of a sidewall of the container or into a retrofit influencer mounted proximate the container; and a power coupler, coupled to the temperature source, for receiving a power line coupled to a power source for operating the temperature source. In a preferred embodiment, the container is adapted to operate in conjunction with a power mixer.

Abstract: Disclosed is an apparatus, including a shaft; a scoop, coupled to a distal end of the shaft, for collecting and holding a bolus of a compressible medium, the compressible medium retaining a post-compressed shape when operated from a proximal end of the shaft; and a former, coupled to the scoop and mating with the scoop, for molding and compressing the bolus into a generally spherical ball retained within the scoop. A method for forming a throwable ball, includes scooping a bolus of a compressible medium with a scoop coupled to a distal end of a shaft, the compressible medium retaining a post-compressed shape; and molding compressively the bolus into the scoop using a former coupled to the distal end, wherein the molding step creates the ball retained in the scoop when a user operates a proximal end of the shaft.

Abstract: Disclosed is an apparatus, including a shaft; a scoop, coupled to a distal end of the shaft, for collecting and holding a bolus of a compressible medium, the compressible medium retaining a post-compressed shape when operated from a proximal end of the shaft; and a former, coupled to the scoop and mating with the scoop, for molding and compressing the bolus into a generally spherical ball retained within the scoop. A method for forming a throwable ball, includes scooping a bolus of a compressible medium with a scoop coupled to a distal end of a shaft, the compressible medium retaining a post-compressed shape; and molding compressively the bolus into the scoop using a former coupled to the distal end, wherein the molding step creates the ball retained in the scoop when a user operates a proximal end of the shaft.