Patents by Inventor Andrew DeBrecht
Andrew DeBrecht has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230183727Abstract: Compositions and methods for optimally expressing transgenes in organisms such as bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising the cassettes and methods of expressing are provided. The DNA constructs or expression cassettes of the invention can be used for transformation and expression in plants and bacteria wherein conventional gene expression methods result in decreased expression, negative phenotypes or reduced plant performance.Type: ApplicationFiled: October 15, 2020Publication date: June 15, 2023Applicant: BASF Agricultural Solutions Seed US LLCInventors: Desmond A Moore, Andrew Debrecht, Laura Schouten, Shane Hardin, Brody DeYoung, Jongmin Baek, Shirong Zhang, Soundarya Srirangan, Allan R Wenck
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Publication number: 20220389444Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in any of SEQ ID NO:1-40, 42, 43, 45-48, 50, 51, 52, 54, 56, 58-64, 66, or 67, or the nucleotide sequence set forth in any of SEQ ID NO:69-106, as well as variants and fragments thereof.Type: ApplicationFiled: February 9, 2022Publication date: December 8, 2022Inventors: Gabriel MILLER, Ethan DUNN, James DOROGHAZI, Duane LEHTINEN, Laura SCHOUTEN, Andrew DEBRECHT, Jonathan GIEBEL, Daniel VAKNIN, Xunhai ZHENG, Kathleen PITCHER
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Patent number: 11286498Abstract: Compositions and methods for conferring resistance to a plant pathogen are provided. Compositions comprising a coding sequence for a polypeptide having antifungal activity are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in any of SEQ ID NO:1-67, or the nucleotide sequence set forth in any of SEQ ID NO:69-81, 83-95, or 97-106, as well as variants and fragments thereof.Type: GrantFiled: January 18, 2018Date of Patent: March 29, 2022Assignee: BASF AGRICULTURAL SOLUTIONS SEED US LLCInventors: Kathleen Pitcher, Gabriel Miller, Ethan Dunn, James Doroghazi, Daniel Vaknin, Xunhai Zheng, Duane Lehtinen, Laura Schouten, Andrew Debrecht, Jonathan Giebel
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Patent number: 11279946Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in any of SEQ ID NO:1-40, 42, 43, 45-48, 50, 51, 52, 54, 56, 58-64, 66, or 67, or the nucleotide sequence set forth in any of SEQ ID NO:69-106, as well as variants and fragments thereof.Type: GrantFiled: January 18, 2018Date of Patent: March 22, 2022Assignee: BASF ARGICULTURAL SOLUTIONS SEED US LLCInventors: Gabriel Miller, Ethan Dunn, James Doroghazi, Duane Lehtinen, Laura Schouten, Andrew Debrecht, Jonathan Giebel, Daniel Vaknin, Xunhai Zheng, Kathleen Pitcher
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Publication number: 20200123564Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in any of SEQ ID NO:1-40, 42, 43, 45-48, 50, 51, 52, 54, 56, 58-64, 66, or 67, or the nucleotide sequence set forth in any of SEQ ID NO:69-106, as well as variants and fragments thereof.Type: ApplicationFiled: January 18, 2018Publication date: April 23, 2020Inventors: Gabriel MILLER, Ethan DUNN, James DOROGHAZI, Duane LEHTINEN, Laura SCHOUTEN, Andrew DEBRECHT, Jonathan GIEBEL, Daniel VAKNIN, Xunhai ZHENG, Kathleen PITCHER
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Publication number: 20190352665Abstract: Compositions and methods for conferring resistance to a plant pathogen are provided. Compositions comprising a coding sequence for a polypeptide having antifungal activity are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in any of SEQ ID NO:1-67, or the nucleotide sequence set forth in any of SEQ ID NO:69-81, 83-95, or 97-106, as well as variants and fragments thereof.Type: ApplicationFiled: January 18, 2018Publication date: November 21, 2019Inventors: Kathleen PITCHER, Gabriel MILLER, Ethan DUNN, James DOROGHAZI, Daniel VAKNIN, Xunhai ZHENG, Duane LEHTINEN, Laura SCHOUTEN, Andrew DEBRECHT, Jonathan GIEBEL
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Publication number: 20120185969Abstract: Compositions and methods for increasing expression of a polypeptide of interest in a plant or plant part thereof are provided. Compositions of the invention are polynucleotide constructs comprising (a) at least one translational enhancer element derived from a virus tandemly stacked with at least one translational enhancer element derived from a cellular gene, and (b) an operably linked polynucleotide encoding a polypeptide of interest. Expression cassettes, vectors, and transgenic plants and plant parts comprising these polynucleotide constructs are also provided. Methods for increasing expression of a polypeptide of interest in a plant or plant part thereof utilizing the polynucleotide constructs and expression cassettes of the invention are also provided.Type: ApplicationFiled: September 2, 2010Publication date: July 19, 2012Inventors: Andrew DeBrecht, Kasimalai Azhakanandam
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Patent number: 8124841Abstract: The present invention is directed to C-terminal truncated ?-amylase polypeptides, nucleic acid sequences encoding the truncated ?-amylase polypeptides, and methods of using the same. Further provided are expression cassettes, plants and plant parts expressing the nucleic acid sequence encoding the truncated ?-amylase. Expression of the truncated ?-amylase in a plant cell results in enhanced accumulation of biologically-active ?-amylase, or enhanced secretion of the ?-amylase from the plant cell, compared to the accumulation or secretion of a full length ?-amylase.Type: GrantFiled: October 22, 2009Date of Patent: February 28, 2012Assignee: Syngenta Participations AGInventors: Andrew DeBrecht, Aron Silverstone, Yan Zhang, Shengsheng Zhang, Xuejun Zhong
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Publication number: 20100100983Abstract: The present invention is directed to C-terminal truncated ?-amylase polypeptides, nucleic acid sequences encoding the truncated ?-amylase polypeptides, and methods of using the same. Further provided are expression cassettes, plants and plant parts expressing the nucleic acid sequence encoding the truncated ?-amylase. Expression of the truncated ?-amylase in a plant cell results in enhanced accumulation of biologically-active ?-amylase, or enhanced secretion of the ?-amylase from the plant cell, compared to the accumulation or secretion of a full length ?-amylase.Type: ApplicationFiled: October 22, 2009Publication date: April 22, 2010Applicant: SYNGENTA PARTICIPATIONS AGInventors: Andrew DeBrecht, Aron Silverstone, Yan Zhang, Shengsheng ZHANG, Xuejun Zhong