Abstract: A glucose monitoring system comprising a readhead positioned a predetermined distance from a sample aperture. The readhead comprises first and second LEDs adapted to emit intersecting paths of light. A beam splitter is positioned at the intersection of the light paths. The beam splitter comprises a band pass filter for controlling the center wavelength of a resulting coaxial emitted light for illuminating a sample on the sample aperture. The readhead further comprises a detector which comprises a detector aperture and a molded lens over the detector aperture. A light-scattering section upstream of the lens comprises a plurality of steps having angles greater than 90 degrees to reduce internal stray light.

Abstract: Formats for optical analysis of fluid samples are provided with platforms and wells for contacting fluid samples and bringing reagents in contact with fluid samples. Formats may be made in opposing platform-and-well constructions, allowing a platform protruding from one format member to enter a well contained within an opposing format member. A sample fill nose accepts sample fluid from a sample collection opening and transports the sample fluid through the format.

Abstract: A disposable optical format for lancing the skin of a patient and harvesting blood to determine blood chemistries such as glucose level includes a housing with openings defining an optical path. A translucent hollow capillary tube with multiple planar sides and an end cleaved to a sharp edge is mounted in the housing. The sides of the tube are formed of an optical material such as fused silica. Significantly less pain, high probability of blood harvesting and improved overall test time are achieved with integrating the lance, harvest and analysis operation.

Abstract: A fiber optic diffuse light reflectance sensor is disclosed. The sensor employs illumination optical fibers to carry light emitted from a high-intensity, narrow bandwidth LED to a baffle in a readhead where the optical fibers reflect the light off of a reagent test strip. The illumination optical fibers are randomly oriented to create a more uniform light source. The light is reflected off of a pad on a reagent test strip to detect the presence of non-hemolyzed trace and hemolyzed occult blood. The reflected light must pass through another baffle to a bi-convex lens where it is focused onto a detection bundle of optical fibers. The detection bundle is optically coupled with a CCD, where the optical signal is converted to an electrical one for processing and analysis.

Abstract: A diffused light reflectance readhead is disclosed. The readhead employs an improved light emitting diode (LED) providing a more strongly collimated beam of fight around a beam axis onto a reagent test pad. The reagent test pad is supported on a strip guide at an angle .alpha. of 5 degrees with respect to the perpendicular of the beam axis. It has been discovered that when .alpha. is between 3 and 8 degrees that specular reflection is dramatically reduced in relation to the small reduction in reflected light received by a sensor. The diffuse reflected light travels to the sensor by passing through a staircase optical baffle at an angle of 45 degrees to the perpendicular of the beam axis. The sensor converts the optical signal into an electrical one for processing and analysis. One embodiment of the present invention can detect the presence of glucose in a blood sample.

Abstract: A diffused light reflectance readhead is disclosed. The readhead employs an improved light emitting diode (LED) providing a more strongly collimated beam of light around a beam axis onto a reagent test pad. The reagent test pad is supported on a strip guide at an angle .alpha. of 5 degrees with respect to the perpendicular of the beam axis. It has been discovered that when .alpha. is between 3 and 8 degrees that specular reflection is dramatically reduced in relation to the small reduction in reflected light received by a sensor. The diffuse reflected light travels to the sensor by passing through a staircase optical baffle at an angle of 45 degrees to the perpendicular of the beam axis. The sensor converts the optical signal into an electrical one for processing and analysis. One embodiment of the present invention can detect the presence of glucose in a blood sample.

Abstract: A reflectance photometer for quantitatively measuring diffuse light includes a light source located above a sample. The reflectance photometer also includes a first detector mounted at a preselected scattering angle relative to an axis extending perpendicularly from the sample through the light source. A first linear polarizer is mounted between the sample and the light source. The direction of polarization of the first linear polarizer is vertical to a scattering plane defined by the direction of incoming light from the light source and the direction of reflected light detected by the first detector. A second linear polarizer is mounted between the sample and the first detector. The direction of the second polarizer is parallel to the scattering plane. The reflectance photometer can include a second detector mounted at a second, scattering angle. A third linear polarizer is mounted between the sample and the second detector.