Abstract: This invention provides Degronimers that have carbon-linked E3 Ubiquitin Ligase targeting moieties (Degrons), which can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation.

Abstract: A method an apparatus for providing speed control in a spindle system are provided. The apparatus includes an air turbine spindle that rotates at a speed, an electromagnetic device coupled to the spindle for creating a torque to maintain a desired speed of the spindle, and a tachometer for generating a measurement of the rotational speed of the spindle. The electromagnetic device applies a torque to the spindle in response to the measurement to change the speed of the spindle to the desired speed.

Abstract: A device for controlling a fluid flow is disclosed. The device includes at least two fluid flow drivers, a plenum disposed to receive a fluid flow from the at least two drivers, and a baffle disposed within the plenum. The plenum has a first cross-sectional area proximate the at least two drivers and a second cross-section area at a distance from the at least two drivers, the second cross-sectional area being an exit for the fluid flow. The baffle has a first edge restrained proximate the first cross-sectional area and a second opposing edge freely disposed proximate the second cross-sectional area. The baffle has a surface area responsive to the fluid flow within the plenum to reduce a backflow if one of the at least two drivers is operational and another is non-operational.