Abstract: There is provided a fit testing method comprising: providing a respirator donned by a wearer; providing a sensor in electrical communication with a sensing element, where the sensor is configured to monitor a particulate concentration parameter of a gas space within the respirator, and a second particulate concentration parameter of a gas space outside the respirator, where the sensor is attached to the respirator such that the respirator such that the weight of the sensor is supported by the respirator; and providing a reader configured to communicate with the sensor, where the reader is configured to provide a respirator fit parameter based on a comparison of the particulate concentration within the respirator to the particulate concentration parameter outside the respirator.

Abstract: The present invention provides and NMR apparatus comprising an analyte sample holder having a containment region that holds a volume of less than about 1 microliters of the analyte sample, a coil, which encloses the containment region of the analyte sample holder and the analyte sample contained therein, the coil operatively associated with the analyte sample contained in the containment region of the analyte sample holder such that the coil can transmit and/or receive energy from the analyte sample in the containment region of the analyte sample holder, and a magnet to provide a static magnetic field in which the coil and the analyte sample in the containment region of the analyte sample holder are located, wherein the coil and the magnet provide for the obtainment of an NMR spectrum having a spectral line width resolution of less than about 0.1 parts per million.

Abstract: An apparatus for obtaining multiple spectra from a plurality of samples through the use of nuclear magnetic resonance (NMR) spectroscopy. A plurality of microcoils are coupled to and are in operable communication with an NMR spectrometer. The coils are operable in both a transmit mode and a receive mode to transmit RF energy to a sample being analyzed and to receive the return data for analysis by the NMR spectrometer. At least one switch is coupled to the plurality of coils and the NMR spectrometer. A controller for the NMR spectrometer is coupled to the switch and is used to control alternative activation of the coils for NMR data acquisition of multiple samples.

Abstract: The present invention provides an NMR apparatus comprising an analyte sample holder having a containment region that holds a volume of less than about 10 microliters of the analyte sample, a microcoil, which encloses the containment region of the analyte sample holder and the analyte sample contained therein, the microcoil having an inside dimension of less than about 1 mm, and the microcoil operatively associated with the analyte sample contained in the containment region of the analyte sample holder such that the microcoil can transmit and/or receive energy from the analyte sample in the containment region of the analyte sample holder, and a magnet having a mass less than about 50 kg, the magnet positioned about the microcoil and the analyte sample in the containment region of the analyte sample holder to provide a static magnetic field in which the microcoil and the analyte sample in the containment region of the analyte sample holder are located, wherein the microcoil and the magnet provide for the obtain

Abstract: An apparatus and method for compensation of magnetic susceptibility variation in NMR microspectroscopy detection microcoils. NMR detection microcoils are formed with side-by-side windings in order to approximate a uniform cylindrical sheet coil. The wire may have a thin layer of insulation in order to prevent shorting between adjacent turns, or (if the wire diameter is small enough) uninsulated wire may be wound with the adjacent turns touching without fear of shorting between coil turns. Additionally, a susceptibility matching medium, such as a perfluorinated hydrocarbon, may be placed around the microcoil to minimize susceptibility-induced variations in the B.sub.0 magnetic field.

Abstract: A method and apparatus for structural elucidation and determination of a nanoliter size sample of analyte. The method includes separating the analyte using a microseparation technique and then substantially simultaneously analyzing or detecting the sample using a nuclear magnetic resonance (NMR) spectrometer. The apparatus includes an RF microcoil positioned for operable communication with a capillary member of the microseparation system and the NMR spectrometer to provide enhanced sensitivity and improved signal-to-noise ratio of the NMR spectrometer necessary to accurately analyze or detect nanoliter size samples.