Abstract: A microfluidic exosome profiling platform integrating exosome isolation and targeted proteomic analysis is disclosed. This platform is capable of quantitative exosomal biomarker profiling directly from 30 ?L plasma samples within approximately 100 minutes with markedly enhanced sensitivity and specificity. Identification of distinct subpopulation of patient-derived exosomes is demonstrated by probing surface proteins and multiparameter analyses of intravesicular biomarkers in the selected subpopulation. The expression of IGF-1R and its phosphorylation level in non-small cell lung cancer (NSCLC) patient plasma is assessed, as a non-invasive alternative to the conventional biopsy and immunohistochemistry.

Abstract: Chemistry game systems and methods are provided. The systems and methods provide an analog and a video portion which may be employed together or separate. Characters in the game battle each other and the outcomes may be based on character statistics and or chance. When employed together the video portion may display a graphical display of an interaction that takes place between the characters in the analog game.

Abstract: A microfluidic exosome profiling platform integrating exosome isolation and targeted proteomic analysis is disclosed. This platform is capable of quantitative exosomal biomarker profiling directly from 30 ?L plasma samples within approximately 100 minutes with markedly enhanced sensitivity and specificity. Identification of distinct subpopulation of patient-derived exosomes is demonstrated by probing surface proteins and multiparameter analyses of intravesicular biomarkers in the selected subpopulation. The expression of IGF-1R and its phosphorylation level in non-small cell lung cancer (NSCLC) patient plasma is assessed, as a non-invasive alternative to the conventional biopsy and immunohistochemistry.

Abstract: A compliance activity information management and control system and method distributes, collates and tracks automated assurance questions and answers directly from key stakeholders to enable faster decision making, higher quality results and lower delivery costs. Additional features include a question-handling system, an exception reporting system and a social community area. The system also provides a graphical representation in a form of a dashboard on the graphical user interface to assist the management of the facility in managing the facility. Function-specific content, incorporates client and industry best practices.

Abstract: Compositions which act synergistically to inhibit the growth of cancer cells and methods of use thereof are disclosed.

Abstract: A business activity information management and control system and method distributes, collates and tracks automated assurance questions and answers directly from key stakeholders to enable faster decision making, higher quality results and lower delivery costs. Additional features include a question-handling system, an exception reporting system and a social community area. The system also provides a graphical representation in a form of a dashboard on the graphical user interface to assist the management of the facility in managing the facility. Function-specific content, incorporates client and industry best practices.

Abstract: Compositions which act synergistically to inhibit the growth of cancer cells and methods of use thereof are disclosed.

Abstract: A shoulder brace consists of a figure "8" strap tensioned between a lower loop anchored around a thigh and a collar or sleeve worn on an opposite upper arm corresponding to an injured shoulder so as to extend the upper loop diagonally across the torso, thereby immobilizing the upper arm to prevent shoulder abduction and external rotation after, for example, shoulder dislocation. The upper and lower loops crossover adjacent the hip, with lower loop snugged under the crotch so as to allow relatively unrestricted movement of the thigh, for example, during exercise. The shoulder brace is thus well adapted for use as a sports brace.