Patents by Inventor Andrew Goetze

Andrew Goetze has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for refolding of recombinant antibodies
    Patent number: 7928205
    Abstract: The present invention is generally directed to methods of producing an increase in the enrichment or recovery of preferred forms of IgG proteins. More particularly, the invention relates to subjecting preparations of such recombinant IgG proteins with a reduction/oxidation coupling reagent and optionally a chaotropic agent.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: April 19, 2011
    Assignee: Amgen Inc.
    Inventors: Thomas M. Dillon, Douglas Rehder, Pavel Bondarenko, Margaret Ricci, Himanshu S. Gadgil, Douglas D. Banks, Joe Zhou, Yuefeng Lu, Andrew Goetze, Yuling Zhang
  • Methods for purifying protein
    Publication number: 20070010661
    Abstract: A method is provided for separating a protein from one or more other proteins using hydroxyapatite chromatography in which the protein does not bind to hydroxyapatite but the other protein(s) does. In some embodiments, a second protein affixed to a solid support has been used previously to purify the protein by affinity chromatography, and small amounts of the second protein are introduced in the sample during this process. The protein being purified can comprise at least one constant antibody immunoglobulin domain. The second protein can bind to proteins comprising such a domain.
    Type: Application
    Filed: September 13, 2006
    Publication date: January 11, 2007
    Applicant: Immunex Corporation
    Inventors: Ganesh Vedantham, Clayton Brooks, Joanne Reeder, Andrew Goetze