Patents by Inventor Andrew J. Ro
Andrew J. Ro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11851522Abstract: A polymeric material includes a polyisobutylene-polyurethane block copolymer. The polyisobutylene-polyurethane block copolymer includes soft segments, hard segments, and end groups. The soft segments include a polyisobutylene diol residue. The hard segments include a diisocyanate residue. The end groups are bonded by urea bonds to a portion of the diisocyanate residue. The end groups include a residue of a mono-functional amine.Type: GrantFiled: September 23, 2022Date of Patent: December 26, 2023Assignee: CARDIAC PACEMAKERS, INC.Inventors: Joseph T. Delaney, Jr., Andrew J. Ro, David R. Wulfman, Niraj Gurung, Patrick Willoughby
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Publication number: 20230018482Abstract: A polymeric material includes a polyisobutylene-polyurethane block copolymer. The polyisobutylene-polyurethane block copolymer includes soft segments, hard segments, and end groups. The soft segments include a polyisobutylene diol residue. The hard segments include a diisocyanate residue. The end groups are bonded by urea bonds to a portion of the diisocyanate residue. The end groups include a residue of a mono-functional amine.Type: ApplicationFiled: September 23, 2022Publication date: January 19, 2023Inventors: Joseph T. Delaney, Andrew J. Ro, David R. Wulfman, Niraj Gurung, Patrick Willoughby
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Patent number: 11472911Abstract: A polymeric material includes a polyisobutylene-polyurethane block copolymer. The polyisobutylene-polyurethane block copolymer includes soft segments, hard segments, and end groups. The soft segments include a polyisobutylene diol residue. The hard segments include a diisocyanate residue. The end groups are bonded by urea bonds to a portion of the diisocyanate residue. The end groups include a residue of a mono-functional amine.Type: GrantFiled: January 15, 2019Date of Patent: October 18, 2022Assignee: Cardiac Pacemakers, Inc.Inventors: Joseph T. Delaney, Jr., Andrew J. Ro, David R. Wulfman, Niraj Gurung, Patrick Willoughby
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Publication number: 20220249676Abstract: A chemotherapy agent comprising a chemotherapy group and a ligand secured to the chemotherapy group is disclosed, the ligand comprising a reactive group capable of bonding to a capture substrate. A method of removing chemotherapy agents from a patient is disclosed, the method comprising providing a chemotherapy agent containing a reactive group; providing a capture substrate in contact with a patient's bloodstream; administering the chemotherapy agent to the patient; and sequestering the chemotherapy agent on the capture substrate. A system for removing chemotherapy agents is also disclosed.Type: ApplicationFiled: May 11, 2020Publication date: August 11, 2022Inventors: Joseph Thomas Delaney, JR., Sarah Melissa Gruba, Tatyana Dyndikova, Paul Vincent Grosso, Amanda Maxwell, Ajay Gupta, Andrew J. Ro, Douglas Pennington
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Patent number: 11213596Abstract: An imaging contrast composition comprising an iodinated contrast agent and a ligand secured to the iodinated contrast agent is disclosed, the ligand comprising a reactive group capable of bonding to a capture substrate. A method of removing iodinated radiocontrast agents from a patient is disclosed, the method comprising providing an iodinated radiocontrast agent containing a reactive group; providing a capture substrate for insertion into a patient's bloodstream; administering the iodinated radiocontrast agent to the patient; conducting procedure CT scan or procedure using fluoroscopy; and sequestering the iodinated radiocontrast agent on the capture substrate.Type: GrantFiled: February 14, 2019Date of Patent: January 4, 2022Assignee: Boston Scientific Scimed, Inc.Inventors: Joseph Thomas Delaney, Jr., Douglas Dean Pagoria, Richard Lee Tadsen, Andrew J. Ro, Joel T. Eggert, Douglas Pennington, Paul Sorajja, Sarah Melissa Gruba, Tatyana Dyndikova
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Publication number: 20210170069Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.Type: ApplicationFiled: February 19, 2021Publication date: June 10, 2021Inventors: Joseph Thomas Delaney, JR., Patrick Willoughby, David Robert Wulfman, Andrew J. Ro, Niraj Gurung
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Patent number: 10925998Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous, interpenetrating polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.Type: GrantFiled: April 23, 2018Date of Patent: February 23, 2021Assignee: Boston Scientific Scimed, Inc.Inventors: Joseph Thomas Delaney, Jr., Patrick Willoughby, David Robert Wulfman, Andrew J. Ro, Niraj Gurung
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Patent number: 10835638Abstract: A block copolymer including a plurality of polymeric chains and a plurality of cross-linking compound residues linking together the plurality of polymeric chains. The plurality of polymeric chains forms a plurality of hard domains and a plurality of soft domains. Each polymeric chain includes a plurality of soft segments and a plurality of hard segments. The plurality of soft segments includes a polyisobutylene diol or diamine residue. The plurality of soft segments forms the plurality of soft domains. The plurality of hard segments including a diisocyanate residue. The plurality of hard segments forms the plurality of hard domains. The cross-linking compound residues link together the hard segments of the plurality of polymeric chains.Type: GrantFiled: August 16, 2018Date of Patent: November 17, 2020Assignee: Cardiac Pacemakers, Inc.Inventors: Joseph T. Delaney, Jr., David R. Wulfman, Patrick Willoughby, Andrew J. Ro
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Patent number: 10526429Abstract: A method for making a polyisobutylene diol from a polyisobutylene diallyl. The method includes hydroborating the polyisobutylene diallyl to produce a polyisobutylene dialkyl borane, and oxidizing the polyisobutylene dialkyl borane to form the polyisobutylene diol. The polyisobutylene diallyl is hydroborated by combining in situ the polyisobutylene diallyl with a borane-coordinating solvent, an alkaline metal salt of borohydride, and an acid. The alkaline metal salt of borohydride is combined with the polyisobutylene diallyl before the acid is combined with the polyisobutylene diallyl.Type: GrantFiled: March 7, 2018Date of Patent: January 7, 2020Assignee: Cardiac Pacemakers, Inc.Inventors: Joseph T. Delaney, Jr., Andrew J. Ro, Patrick Willoughby, Niraj Gurung
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Publication number: 20190275178Abstract: An imaging contrast composition comprising an iodinated contrast agent and a ligand secured to the iodinated contrast agent is disclosed, the ligand comprising a reactive group capable of bonding to a capture substrate. A method of removing iodinated radiocontrast agents from a patient is disclosed, the method comprising providing an iodinated radiocontrast agent containing a reactive group; providing a capture substrate for insertion into a patient's bloodstream; administering the iodinated radiocontrast agent to the patient; conducting procedure CT scan or procedure using fluoroscopy; and sequestering the iodinated radiocontrast agent on the capture substrate.Type: ApplicationFiled: February 14, 2019Publication date: September 12, 2019Inventors: Joseph Thomas Delaney, Douglas Dean Pagoria, Richard Lee Tadsen, Andrew J. Ro, Joel T. Eggert, Douglas Pennington, Paul Sorajja, Sarah Melissa Gruba, Tatyana Dyndikova
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Publication number: 20190218334Abstract: A polymeric material includes a polyisobutylene-polyurethane block copolymer. The polyisobutylene-polyurethane block copolymer includes soft segments, hard segments, and end groups. The soft segments include a polyisobutylene diol residue. The hard segments include a diisocyanate residue. The end groups are bonded by urea bonds to a portion of the diisocyanate residue. The end groups include a residue of a mono-functional amine.Type: ApplicationFiled: January 15, 2019Publication date: July 18, 2019Inventors: Joseph T. Delaney, JR., Andrew J. Ro, David R. Wulfman, Niraj Gurung, Patrick Willoughby
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Publication number: 20190054204Abstract: A block copolymer including a plurality of polymeric chains and a plurality of cross-linking compound residues linking together the plurality of polymeric chains. The plurality of polymeric chains forms a plurality of hard domains and a plurality of soft domains. Each polymeric chain includes a plurality of soft segments and a plurality of hard segments. The plurality of soft segments includes a polyisobutylene diol or diamine residue. The plurality of soft segments forms the plurality of soft domains. The plurality of hard segments including a diisocyanate residue. The plurality of hard segments forms the plurality of hard domains. The cross-linking compound residues link together the hard segments of the plurality of polymeric chains.Type: ApplicationFiled: August 16, 2018Publication date: February 21, 2019Inventors: Joseph T. Delaney, JR., David R. Wulfman, Patrick Willoughby, Andrew J. Ro
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Publication number: 20180303972Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous, interpenetrating polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.Type: ApplicationFiled: April 23, 2018Publication date: October 25, 2018Inventors: Joseph Thomas Delaney, JR., Patrick Willoughby, David Robert Wulfman, Andrew J. Ro, Niraj Gurung
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Publication number: 20180258196Abstract: A method for making a polyisobutylene diol from a polyisobutylene diallyl. The method includes hydroborating the polyisobutylene diallyl to produce a polyisobutylene dialkyl borane, and oxidizing the polyisobutylene dialkyl borane to form the polyisobutylene diol. The polyisobutylene diallyl is hydroborated by combining in situ the polyisobutylene diallyl with a borane-coordinating solvent, an alkaline metal salt of borohydride, and an acid. The alkaline metal salt of borohydride is combined with the polyisobutylene diallyl before the acid is combined with the polyisobutylene diallyl.Type: ApplicationFiled: March 7, 2018Publication date: September 13, 2018Inventors: Joseph T. Delaney, JR., Andrew J. Ro, Patrick Willoughby, Niraj Gurung