Patents by Inventor Andrew Lorenzo

Andrew Lorenzo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion proteins and methods for site-directed genome editing
    Patent number: 11976309
    Abstract: In some aspects, the present invention provides methods and compositions for modifying target sites within nucleic acid molecules. In some embodiments, the methods comprise using adenosine deaminases that act on RNA (ADARs), and variants thereof, to modify target sites within DNA-RNA hybrid molecules. In other aspects, ADAR2 variant polypeptides as well as fusion proteins comprising an ADAR catalytic domain and a hybrid nucleic acid binding domain are provided, as are methods for use thereof. Methods for preventing and treating genetic disorders are also provided herein.
    Type: Grant
    Filed: June 13, 2022
    Date of Patent: May 7, 2024
    Assignee: The Regents of the University of California
    Inventors: Yuxuan Zheng, Claire Lorenzo, Peter Beal, Andrew Fisher, Leanna Monteleone
  • Armor-piercing cavitation projectile
    Patent number: 10036619
    Abstract: A projectile has a body with an axis and a meplat disposed substantially orthogonal to the axis. The meplat is bounded by a substantially square edge.
    Type: Grant
    Filed: January 11, 2016
    Date of Patent: July 31, 2018
    Assignee: Lehigh Defense, LLC
    Inventors: David B. Fricke, Andrew Lorenzo
  • ARMOR-PIERCING CAVITATION PROJECTILE
    Publication number: 20170199019
    Abstract: A projectile has a body with an axis and a meplat disposed substantially orthogonal to the axis. The meplat is bounded by a substantially square edge.
    Type: Application
    Filed: January 11, 2016
    Publication date: July 13, 2017
    Applicant: Lehigh Defense, LLC
    Inventors: David B. Fricke, Andrew Lorenzo