Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.

Abstract: A oscillator having two synchronized oscillator rings is described. Synchronization is accomplished by circuitry connected between the outputs of two aligned stages in coupled oscillator rings, the circuitry being operable to maintain outputs of the stages 180.degree. apart in phase.

Abstract: A frequency doubler is described which is capable of receiving four input signals in quadrature and combining them to produce a pair of antiphase output signals at twice the input frequency.

Abstract: A quadrature oscillator is provided constructed of NOR gates in the manner of a non-linear circuit which is inherently unstable and which cycles sequentially through four distinct states at a rate determined by the constitution of the NOR gates. The quadrature oscillator includes first and second stages that each include first and second NOR gates. The output of the first NOR gate of the first stage is connected as an input to the second NOR gate of each of the first and second stages. The output of the second NOR gate of the first stage is connected as an input to the first NOR gate of each of the first and second stages. The output of the first NOR gate of the second stage is connected as an input to the first NOR gate of the first stage and the second NOR gate of the second stage. The output of the second NOR gate of the second stage is connected as and input to the second NOR gate of the first stage and the first NOR gate of the second stage.

Abstract: A ring oscillator having an odd number of single ended stages, each stage including two transistors connected as a current mirror. The stage provides for low-voltage performance and improved process tolerance characteristics.

Abstract: A switching circuit for an FET transistor includes a controlled current circuit coupled to the gate of the FET. The input to the controlled current circuit represents a desired rate of change of gate voltage of the FET and is generated by a circuit responsive to the average specific transconductance of two FETs of similar specific transconductance operating at different drain circuit densities.

Abstract: A voltage controlled oscillator comprises a plurality of differential amplification stages each arranged to introduce a phase shift between its differential input signal and its differential output signal. The frequency at which the desired phase shift occurs can be controlled by adjusting the control signal Vc. The stages are arranged such that the output of one amplifier becomes the input to the next amplifier, making the phase shift additive. Further, a phase shift of 180.degree. may be introduced by inverting the output from one stage before inputting it to the next stage. The total phase shift introduced by the stages is 360.degree.. In this way, an oscillating signal of varying phase shift is produced at the output of each stage. Each stage comprises a standard differential amplifier, well known in the art, having a matched pair of p-channel transistors and a matched pair of n-channel transistors.

Abstract: A ring oscillator having an odd number of single ended stages, each stage including two transistors connected as a current mirror. The stage provides for low-voltage performance and improved process tolerance characteristics.