Abstract: The invention provides an adaptor for a medicament delivery device is configured to enable a set dosage of a medicament to be drawn into and/or expelled from the device, the adaptor including: a body configured to be coupled to the device; an attachment portion movable with respect to the body and configured for attachment with a first part of the device; an engaging portion movable with the attachment portion; and a receiver configured to receive a movement constraint guide (MCG) and facilitate engagement between the engaging portion and the MCG; wherein the MCG includes one or more physical features defining at least an aspect of the set dosage; and wherein activation of said first part of the device to draw and/or expel the medicament is stopped when the set dosage is reached by engagement between the engaging portion and at least one of the one or more physical features of the MCG.

Abstract: A network node may contain a virtual software-defined networking (SDN) switch and a local a management engine (e.g., a software application) for generating performance metrics based on received management plane traffic. Specifically, the virtual SDN switch may identify and forward received management plane traffic to the local management engine. In turn, the management engine evaluates the management plane traffic to generate performance metrics without forwarding the management plane packets to the remote SDN controller. The management engine may compare the metrics to one or more thresholds to determine the current state or health of the data paths in a network. If a threshold is exceeded, the management engine may transmit an alert to the virtual SDN switch to perform a corrective action—e.g., using a backup data path after the primary data path fails.

Abstract: The present disclosure provides a compound of the following formula, racemates, enantiomers, prodrugs and salts thereof: Also provided is the use of these compounds for the treatment of ischemia and reperfusion injuries. Further applications include the treatment of diseases caused by cell apoptosis and/or cell necrosis.

Abstract: A content distribution platform (1) is arranged to distribute content by streaming over a communications network (4). The consumer (3) provides the content distributor (1) with marker data indicating where secondary content is to be inserted in a primary content stream. When the primary data is requested from a client platform (3), secondary content is inserted at the markers in the content stream. The secondary content to be inserted may be advertising material, data related to the primary data, or topical subjects, selected according to one or more characteristics associated with the client platform (3).