Abstract: The present disclosure provides humanized and affinity matured antibodies (mAbs) and fragments thereof that specifically bind to CD79 with high affinity. The anti-CD79 mAbs and fragments thereof can be used to treat antibody-associated conditions, including autoimmune diseases, allergies, transplant rejection, or immune-mediated rejection of a therapeutics optionally in combination with an additional therapeutic agent. Furthermore, the anti-CD79 mAbs and fragments thereof can be used for diagnostic purposes, including to detect CD79 cells in biological samples and to diagnose B-cell associated disorders.

Abstract: The present disclosure provides humanized and affinity matured antibodies (mAbs) and fragments thereof that specifically bind to CD79 with high affinity. The anti-CD79 mAbs and fragments thereof can be used to treat antibody-associated conditions, including autoimmune diseases, allergies, transplant rejection, or immune-mediated rejection of a therapeutics optionally in combination with an additional therapeutic agent. Furthermore, the anti-CD79 mAbs and fragments thereof can be used for diagnostic purposes, including to detect CD79 cells in biological samples and to diagnose B-cell associated disorders.

Abstract: The present disclosure provides humanized and affinity matured antibodies (mAbs) and fragments thereof that specifically bind to CD79 with high affinity. The anti-CD79 mAbs and fragments thereof can be used to treat antibody-associated conditions, including autoimmune diseases, allergies, transplant rejection, or immune-mediated rejection of a therapeutics optionally in combination with an additional therapeutic agent. Furthermore, the anti-CD79 mAbs and fragments thereof can be used for diagnostic purposes, including to detect CD79 cells in biological samples and to diagnose B-cell associated disorders.

Abstract: Systems and methods are provided for facilitating automated compliance with security, audit and network configuration policies. In some instances, new runtime configuration files are iteratively generated and compared to a baseline configuration file to determine whether a threshold variance exists between the baseline configuration file and each separate and new runtime configuration file. If the threshold variance exists, remedial actions are triggered. In some instances, runtime configuration files are scanned for blacklist configuration settings. When blacklist configuration settings are found, remedial actions can also be triggered. In some instances, configuration files are scrubbed by omitting detected blacklist items from the configuration files. In some instances, changes are only made to configuration files when they match changes on an approved change list and are absent from an open incident list.

Abstract: Systems and methods are provided for facilitating automated compliance with security, audit and network configuration policies. In some instances, new runtime configuration files are iteratively generated and compared to a baseline configuration file to determine whether a threshold variance exists between the baseline configuration file and each separate and new runtime configuration file. If the threshold variance exists, remedial actions are triggered. In some instances, runtime configuration files are scanned for blacklist configuration settings. When blacklist configuration settings are found, remedial actions can also be triggered. In some instances, configuration files are scrubbed by omitting detected blacklist items from the configuration files. In some instances, changes are only made to configuration files when they match changes on an approved change list and are absent from an open incident list.

Abstract: A process of tracking the lifecycle of a network cluster. A method readies a device for provisioning in a network cluster to place the device in a provision ready state. The method further provisions the device to place the device in an in provision state and when provisioned places the device in an in validation state. The method validates the provisioning of the device by, in parallel, validating the automatic configuration operation of the device and validating the human configuration operation of the device when the device is in the in validation state. When the device is validated, the method changes the device state to a production ready state.