Abstract: A system and method for centrally logging and aggregating miscompares on chip during a memory test. The method includes performing, by a built-in self-test (BIST) unit of a memory device, a memory test on one or more memory banks of the memory device using a first algorithm. The method includes generating miscompare results responsive to performing the memory test on the one or more memory banks of the memory device. The method includes determining failure diagnostic information based on the miscompare results. The method includes generating an error packet comprising the failure diagnostic information and the miscompare results. The method includes placing the error packet in a queue of a plurality of error packets to generate a queued error packet.

Abstract: A system and method for centrally logging and aggregating miscompares on chip during a memory test. The method includes performing, by a built-in self-test (BIST) unit of a memory device, a memory test on one or more memory banks of the memory device using a first algorithm. The method includes generating miscompare results responsive to performing the memory test on the one or more memory banks of the memory device. The method includes determining failure diagnostic information based on the miscompare results. The method includes generating an error packet comprising the failure diagnostic information and the miscompare results. The method includes placing the error packet in a queue of a plurality of error packets to generate a queued error packet.

Abstract: The present invention relates to a method for amplifying at least one target RNA in a fixed and, optionally, expanded biological sample. In an embodiment of the invention, the method comprises incubating the fixed biological sample with a pair of polynucleotides complementary to non-overlapping and proximal sequences of a target RNA, wherein the polynucleotide pair hybridizes to the target RNA; ligating the polynucleotide pair using a ligase; and amplifying the ligation product. The invention further provides methods for detecting and optionally quantifying and/or sequencing the amplification product. As the method comprises hybridizing polynucleotide pairs to a target RNA in a fixed biological sample, the target RNA can be hybridized in situ.

Abstract: A novel cycle device including a transmission assembly (or assemblies) that significantly reduces torque interference with steering operations is provided. Such an assembly is provided in one or more of a modular, fixed or movable configuration according reduced complexity of implementation, improved efficiency of operation, and useful assembly modularity for manufacture and repair. Such a device may further include an improved means for selecting between direct and overdrive functions of a fixed transmission assembly. Additionally, a removable front transmission assembly comprising a steering fork with handlebars is also encompassed herein.

Abstract: The invention provides in situ nucleic acid sequencing to be conducted in biological specimens that have been physically expanded. The invention leverages the techniques for expansion microscopy (ExM) to provide new methods for in situ sequencing of nucleic acids in a process referred to herein as “expansion sequencing” (ExSEQ).

Abstract: Systems and methods for multiple beam additive manufacturing use multiple beams of light (e.g., laser light) simultaneously to expose layers of powder material in selected regions until the powder material fuses to form voxels, which form build layers of a three-dimensional structure. The light may be generated from selected light sources and coupled into an array of optical fibers having output ends arranged in an optical head such that the multiple beams are directed by the optical head to different locations on each of the powder layers. The multiple beams may provide distributed exposures forming a distributed exposure pattern including beam spots that are spaced sufficiently to separate the fused regions formed by each exposure. The multiple beams may be moved using various techniques (e.g., by moving the optical head) and according to various scan patterns such that a plurality of multiple beam distributed exposures form each build layer.

Abstract: A novel cycle device including a transmission assembly (or assemblies) that significantly reduces torque interference with steering operations is provided. Such an assembly is provided in one or more of a modular, fixed or movable configuration according reduced complexity of implementation, improved efficiency of operation, and useful assembly modularity for manufacture and repair. Such a device may further include an improved means for selecting between direct and overdrive functions of a fixed transmission assembly. Additionally, a removable front transmission assembly comprising a steering fork with handlebars is also encompassed herein.

Abstract: A novel cycle device including a transmission assembly (or assemblies) that significantly reduces torque interference with steering operations is provided. Such an assembly is provided in one or more of a modular, fixed or movable configuration according reduced complexity of implementation, improved efficiency of operation, and useful assembly modularity for manufacture and repair. Such a device may further include an improved means for selecting between direct and overdrive functions of a fixed transmission assembly. Additionally, a removable front transmission assembly comprising a steering fork with handlebars is also encompassed herein.

Abstract: A novel cycle device including a transmission assembly (or assemblies) that significantly reduces torque interference with steering operations is provided. Such an assembly is provided in one or more of a modular, fixed or movable configuration according reduced complexity of implementation, improved efficiency of operation, and useful assembly modularity for manufacture and repair. Such a device may further include an improved means for selecting between direct and overdrive functions of a fixed transmission assembly. Additionally, a removable front transmission assembly comprising a steering fork with handlebars is also encompassed herein.

Abstract: 4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.

Abstract: The present invention relates to a method for amplifying at least one target RNA in a fixed and, optionally, expanded biological sample. In an embodiment of the invention, the method comprises incubating the fixed biological sample with a pair of polynucleotides complementary to non-overlapping and proximal sequences of a target RNA, wherein the polynucleotide pair hybridizes to the target RNA; ligating the polynucleotide pair using a ligase; and amplifying the ligation product. The invention further provides methods for detecting and optionally quantifying and/or sequencing the amplification product. As the method comprises hybridizing polynucleotide pairs to a target RNA in a fixed biological sample, the target RNA can be hybridized in situ.

Abstract: 4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.

Abstract: A novel cycle device including a transmission assembly (or assemblies) that significantly reduces torque interference with steering operations is provided. Such an assembly is provided in one or more of a modular, fixed or movable configuration according reduced complexity of implementation, improved efficiency of operation, and useful assembly modularity for manufacture and repair. Such a device may further include an improved means for selecting between direct and overdrive functions of a fixed transmission assembly. Additionally, a removable front transmission assembly comprising a steering fork with handlebars is also encompassed herein.

Abstract: The invention provides in situ nucleic acid sequencing to be conducted in biological specimens that have been physically expanded. The invention leverages the techniques for expansion microscopy (ExM) to provide new methods for in situ sequencing of nucleic acids in a process referred to herein as “expansion sequencing” (ExSEQ).

Abstract: 4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.

Abstract: A method includes determining that a mobile computing device is within an enterprise geographic location. The method further includes, when the mobile computing device is within the enterprise geographic location, determining that a user of the mobile computing device is eligible for an enterprise sponsored mobile data service. The method further includes, when the user of the mobile computing device is eligible, determining use parameters for the enterprise sponsored mobile data service. The method further includes registering the mobile computing device for the enterprise sponsored mobile data service with an enterprise server and/or a mobile data service provider. The method further includes the mobile computing device receiving the enterprise sponsored mobile data services in accordance with the use parameters. The method further includes adjusting, by the mobile data service provider, billing rate of the mobile computing device while receiving the enterprise sponsored mobile data service.

Abstract: A novel transmission for cycles that significantly reduces torque interference with steering operations is provided. Such a transmission allows for improved recumbent cycling capabilities. The inventive device thus includes a combination of a fixed transmission assembly that reduces torque levels and a movable transmission assembly that multiplies torque levels, allowing for the avoidance of high torque effects through the vehicle's steering axis. As such, the capability of the overall cycle device to steer properly and to a rather wide angle from center while implementing such a torque transfer protocol allows for a unique recumbent cycle configuration. Such a device, then, may be utilized for a human-powered cycle vehicle or one that further includes an electrical component to allow for automated drive capabilities through a rear wheel or wheels, as well. The method of implementation of such a transmission within a variety of cycle devices is also encompassed within this invention.

Abstract: A method includes determining that a mobile computing device is within an enterprise geographic location. The method further includes, when the mobile computing device is within the enterprise geographic location, determining that a user of the mobile computing device is eligible for an enterprise sponsored mobile data service. The method further includes, when the user of the mobile computing device is eligible, determining use parameters for the enterprise sponsored mobile data service. The method further includes registering the mobile computing device for the enterprise sponsored mobile data service with an enterprise server and/or a mobile data service provider. The method further includes the mobile computing device receiving the enterprise sponsored mobile data services in accordance with the use parameters. The method further includes adjusting, by the mobile data service provider, billing rate of the mobile computing device while receiving the enterprise sponsored mobile data service.

Abstract: Systems and methods for multiple beam additive manufacturing use multiple beams of light (e.g., laser light) simultaneously to expose layers of powder material in selected regions until the powder material fuses to form voxels, which form build layers of a three-dimensional structure. The light may be generated from selected light sources and coupled into an array of optical fibers having output ends arranged in an optical head such that the multiple beams are directed by the optical head to different locations on each of the powder layers. The multiple beams may provide distributed exposures forming a distributed exposure pattern including beam spots that are spaced sufficiently to separate the fused regions formed by each exposure. The multiple beams may be moved using various techniques (e.g., by moving the optical head) and according to various scan patterns such that a plurality of multiple beam distributed exposures form each build layer.

Abstract: Systems and methods for multiple beam additive manufacturing use multiple beams of light (e.g., laser light) to expose layers of powder material in selected regions until the powder material fuses to form voxels, which form build layers of a three-dimensional structure. The light may be generated from selected light sources and coupled into an array of optical fibers having output ends arranged in an optical head in at least one line such that multiple beams are sequentially directed by the optical head to the same powder region providing multiple beam sequential exposures (e.g., with pre-heating, melting and controlled cool down) to fuse the powder region. The multiple sequential beams may be moved using various techniques (e.g., by moving the optical head) and according to various scan patterns such that a plurality of fused regions form each build layer.