Patents by Inventor Andrew Powell

Andrew Powell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210347762
    Abstract: This invention is directed to novel carbocyclic prolinamide derivatives of Formula (I), and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. These diseases include dry-AMD, wet-AMD, geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells. The invention disclosed herein is further directed to methods of prevention, slowing the progress of, and treatment of dry-AMD, wet-AMD, and geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells, comprising: administration of a therapeutically effective amount of compound of the invention.
    Type: Application
    Filed: July 14, 2021
    Publication date: November 11, 2021
    Applicant: ORION OPHTHALMOLOGY LLC
    Inventors: Robert Gomez, Jinyue Ding, Renata Marcella Oballa, David Andrew Powell
  • Patent number: 11091465
    Abstract: This invention is directed to novel carbocyclic prolinamide derivatives of Formula (I), and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. These diseases include dry-AMD, wet-AMD, geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells. The invention disclosed herein is further directed to methods of prevention, slowing the progress of, and treatment of dry-AMD, wet-AMD, and geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells, comprising: administration of a therapeutically effective amount of compound of the invention.
    Type: Grant
    Filed: January 6, 2020
    Date of Patent: August 17, 2021
    Assignee: ORION OPHTHALMOLOGY LLC
    Inventors: Robert Gomez, Jinyue Ding, Renata Marcella Oballa, David Andrew Powell
  • Patent number: 11004196
    Abstract: Methods are herein provided for decision support in diagnosis of a disease in a subject, and for extracting features from a multi-slice data set. Systems for computer-aided diagnosis are provided. The systems take as input a plurality of medical data and produces as output a diagnosis based upon this data. The inputs may consist of a combination of image data and clinical data. Diagnosis is performed through feature selection and the use of one or more classifier algorithms.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: May 11, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Lilla Boroczky, Lalitha Agnihotri, Luyin Zhao, Michael Chun-chieh Lee, Charles Andrew Powell, Alain C. Borczuk, Steven Kawut
  • Patent number: 10968201
    Abstract: Compounds, compositions and methods are provided for modulating the activity of EP2 and EP4 receptors, and for the treatment, prevention and amelioration of one or more symptoms of diseases or disorders related to the activity of EP2 and EP4 receptors. In certain embodiments, the compounds are antagonists of both the EP2 and EP4 receptors.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: April 6, 2021
    Assignee: TEMPEST THERAPEUTICS, INC.
    Inventors: Yalda Bravo, Austin Chih-Yu Chen, Jinyue Ding, Robert Gomez, Heather Lam, Joe Fred Nagamizo, Renata Marcella Oballa, David Andrew Powell, Tao Sheng
  • Publication number: 20210024491
    Abstract: Compounds, compositions and methods are provided for modulating the activity of EP2 and EP4 receptors, and for the treatment, prevention and amelioration of one or more symptoms of diseases or disorders related to the activity of EP2 and EP4 receptors. In certain embodiments, the compounds are antagonists of both the EP2 and EP4 receptors.
    Type: Application
    Filed: October 14, 2020
    Publication date: January 28, 2021
    Inventors: Yalda BRAVO, Austin Chih-Yu CHEN, Jinyue DING, Robert GOMEZ, Heather LAM, Joe Fred NAGAMIZO, Renata Marcella OBALLA, David Andrew POWELL, Tao SHENG
  • Patent number: 10900262
    Abstract: A handle assembly for engaging and disengaging a locking or securing device. The assembly comprises an actuator, and a rotatable exterior handle. In use, the exterior handle rotates the actuator to engage or disengage the locking or securing device. The exterior handle is structured to only rotate and engage the actuator when the exterior handle is removed from its retracted position into its extended position.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: January 26, 2021
    Assignee: Aviation Technical Services, inc.
    Inventors: Andrew Powell, Larry Coburn, Antonio Zuniga, Asia Davis
  • Publication number: 20200385362
    Abstract: This invention is directed to novel carbocyclic prolinamide derivatives of Formula (I), and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. These diseases include dry-AMD, wet-AMD, geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells. The invention disclosed herein is further directed to methods of prevention, slowing the progress of, and treatment of dry-AMD, wet-AMD, and geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells, comprising: administration of a therapeutically effective amount of compound of the invention.
    Type: Application
    Filed: January 6, 2020
    Publication date: December 10, 2020
    Applicant: ORION OPHTHALMOLOGY LLC
    Inventors: Robert Gomez, Jinyue Ding, Renata Marcella Oballa, David Andrew Powell
  • Patent number: 10730832
    Abstract: This invention is directed to novel aliphatic prolinamide derivatives of Formula I, and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. These diseases include dry-AMD, wet-AMD, geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells. The invention disclosed herein is further directed to methods of prevention, slowing the progress of, and treatment of dry-AMD, wet-AMD, and geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells, comprising: administration of a therapeutically effective amount of compound of the invention.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: August 4, 2020
    Assignee: ORION OPHTHALMOLOGY LLC
    Inventors: Austin Chih-Yu Chen, Robert Gomez, Renata Marcella Oballa, David Andrew Powell, Jeffrey Roger Roppe, Thomas Jon Seiders, Tao Sheng
  • Publication number: 20200090209
    Abstract: A system for providing virtual coupons to a customer illustratively includes a database having a plurality of virtual coupons stored therein, a virtual coupon repository associated with the customer, and a virtual coupon module to transfer selected ones of the plurality of virtual coupons stored in the database to the virtual coupon repository, and to sequentially activate for redemption by the customer each successive virtual coupon in the sequence after a preceding virtual coupon in the sequence has been redeemed by the customer. At least one of the selected virtual coupons selected based on one or more items in a purchase history stored in the database and associated in the database with the customer.
    Type: Application
    Filed: November 22, 2019
    Publication date: March 19, 2020
    Inventors: Bhushan Balani, Andrew Powell, Shrineil Patel
  • Patent number: 10562579
    Abstract: A seal for a meter housing with an interior portion is disclosed. The seal includes an axially inner surface configured to face the interior portion of the meter housing and an axially outer surface configured to face away from the interior portion of the meter housing. At least one of the axially inner surface and the axially outer surface is configured to seal against a portion of the housing. The seal further includes a diaphragm defined axially intermediate the axially inner surface and the axially outer surface and a fluid passageway defined through a portion of the diaphragm. The fluid passageway is configured to move between an open position and a closed position in response to a pressure differential between the interior portion of the housing and an exterior portion.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: February 18, 2020
    Assignee: Polaris Industries Inc.
    Inventors: Geoffrey Wotton, Mark Andrew Powell, Benjamin Travis Chambers, Justin Larson
  • Patent number: 10526315
    Abstract: This invention is directed to novel carbocyclic prolinamide derivatives of Formula (I), and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. These diseases include dry-AMD, wet-AMD, geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells. The invention disclosed herein is further directed to methods of prevention, slowing the progress of, and treatment of dry-AMD, wet-AMD, and geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells, comprising: administration of a therapeutically effective amount of compound of the invention.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: January 7, 2020
    Assignee: ORION OPHTHALMOLOGY LLC
    Inventors: Robert Gomez, Jinyue Ding, Renata Marcella Oballa, David Andrew Powell
  • Publication number: 20190390794
    Abstract: The disclosure relates to a clamping device and method of securing a clamping device. The clamping device is suitable for clamping an elongate member, and includes a body portion for surrounding the elongate element and configured to apply a compressive force on the elongate member. The body portion includes at least two outwardly curved plates.
    Type: Application
    Filed: November 27, 2017
    Publication date: December 26, 2019
    Applicant: GE Oil & Gas UK Limited
    Inventors: David Legg, Andrew Powell, Richard David Carverhill
  • Publication number: 20190330146
    Abstract: This invention is directed to novel aliphatic prolinamide derivatives of Formula I, and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. These diseases include dry-AMD, wet-AMD, geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells. The invention disclosed herein is further directed to methods of prevention, slowing the progress of, and treatment of dry-AMD, wet-AMD, and geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells, comprising: administration of a therapeutically effective amount of compound of the invention.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 31, 2019
    Applicant: ORION OPHTHALMOLOGY LLC
    Inventors: Austin Chih-Yu Chen, Robert Gomez, Renata Marcella Oballa, David Andrew Powell, Jeffrey Roger Roppe, Thomas Jon Seiders, Tao Sheng
  • Publication number: 20190322645
    Abstract: This invention is directed to novel heterocyclic prolinamide derivatives of Formula (I), and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., (s) controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. These diseases include dry-AMD, wet-AMD, geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells. The invention disclosed herein is further directed to methods of prevention, slowing the progress of, and treatment of dry-AMD, wet-AMD, and geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells, comprising: administration of a therapeutically effective amount of compound of the invention.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 24, 2019
    Applicant: ORION OPHTHALMOLOGY LLC
    Inventors: Robert Gomez, Jinyue Ding, Renata Marcella Oballa, David Andrew Powell, Maxim Epifanov
  • Publication number: 20190315712
    Abstract: Compounds, compositions and methods are provided for modulating the activity of EP2 and EP4 receptors, and for the treatment, prevention and amelioration of one or more symptoms of diseases or disorders related to the activity of EP2 and EP4 receptors. In certain embodiments, the compounds are antagonists of both the EP2 and EP4 receptors.
    Type: Application
    Filed: April 17, 2019
    Publication date: October 17, 2019
    Inventors: Yalda BRAVO, Austin Chih-Yu CHEN, Jinyue DING, Robert GOMEZ, Heather LAM, Joe Fred NAGAMIZO, Renata Marcella OBALLA, David Andrew POWELL, Tao SHENG
  • Publication number: 20190202810
    Abstract: This invention is directed to novel carbocyclic prolinamide derivatives of Formula (I), and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. These diseases include dry-AMD, wet-AMD, geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells. The invention disclosed herein is further directed to methods of prevention, slowing the progress of, and treatment of dry-AMD, wet-AMD, and geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells, comprising: administration of a therapeutically effective amount of compound of the invention.
    Type: Application
    Filed: June 15, 2017
    Publication date: July 4, 2019
    Applicant: Orion Ophthalmology LLC
    Inventors: Robert GOMEZ, Jinyue DING, Renata Marcella OBALLA, David Andrew POWELL
  • Publication number: 20190108632
    Abstract: Methods are herein provided for decision support in diagnosis of a disease in a subject, and for extracting features from a multi-slice data set. Systems for computer-aided diagnosis are provided. The systems take as input a plurality of medical data and produces as output a diagnosis based upon this data. The inputs may consist of a combination of image data and clinical data. Diagnosis is performed through feature selection and the use of one or more classifier algorithms.
    Type: Application
    Filed: October 5, 2018
    Publication date: April 11, 2019
    Inventors: Lilla Boroczky, Lalitha Agnihotri, Luyin Zhao, Michael Chun-chieh Lee, Charles Andrew Powell, Alain C. Borczuk, Steven Kawut
  • Publication number: 20190011273
    Abstract: A system includes a route-optimization module configured to calculate an efficient route. The module is also configured to utilize modelled vehicle-efficiency data, reflecting expected performance, for determining route efficiency and project driver-specific efficiency along a proposed route. The module is further configured to utilize efficiency-affecting vehicle state data to determine projected state efficiency-impact. The system also includes a guidance module configured to provide real-time guidance targets including gear selection and vehicle speed and provide real-time feedback to the driver comparing observed vehicle performance to the guidance targets.
    Type: Application
    Filed: July 10, 2018
    Publication date: January 10, 2019
    Applicant: FORD GLOBAL TECHNOLOGIES, LLC
    Inventors: Richard Andrew POWELL, Owen Fraser WOOD, Jonathan SCOTT
  • Patent number: 10121243
    Abstract: Methods are herein provided for decision support in diagnosis of a disease in a subject, and for extracting features from a multi-slice data set. Systems for computer-aided diagnosis are provided. The systems take as input a plurality of medical data and produces as output a diagnosis based upon this data. The inputs may consist of a combination of image data and clinical data. Diagnosis is performed through feature selection and the use of one or more classifier algorithms.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: November 6, 2018
    Assignee: Koninklijke Philips N.V.
    Inventors: Lilla Boroczky, Lalitha Agnihotri, Luyin Zhao, Michael Chun-Chieh Lee, Charles Andrew Powell, Alain C. Borczuk, Steven Kawut
  • Patent number: 9977584
    Abstract: A computing device can periodically acquire a current track time for a media content item being played. The device can periodically compare the current track time with a respective start time and a respective end time for each line (or segment) in a plurality of lines of text (or segments of text) associated with the media content item. If the device determines that the current track time is between start and end times for a given line of text, then the device can display the given line of text. A user of the device can scroll through the lines of text associated with the media content item. If the user selects a particular line of text, the device can identify a start time for the selected line of text. The device can then play the media content item at the identified start time of the selected line of text.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: May 22, 2018
    Assignee: AMAZON TECHNOLOGIES, INC.
    Inventors: Toby Ray Latin-Stoermer, Jonathan Beech, Hari Gangadharan, Gabriela Ahern, Brandon Scott Durham, Darren Levi Malek, Ralph Cameron Harvey, Benjamin Lee Shepherd, Jason Christopher Hall, Andrew Powell McGoogan, Robert Richard Morse