Abstract: A system and associated method for concentrating and separating components of different densities from fluid containing cells using a centrifuge includes a container defining a cavity for receiving the fluid. The container has a top, a sidewall extending from the top, and a bottom disposed opposite the top and in sealing engagement with the sidewall. An insert is slidably disposed in the cavity of the container and defines a lumen through the insert. The lumen, which includes a hole and a funnel-shaped upper portion in fluid communication with the hole, forms an open fluid path between opposite ends of the insert. The insert has a density such that upon centrifugation a selected component of the fluid resides within the lumen. A container port is disposed in the top of the container to transfer the fluid into the container and to withdraw a fluid component other than the selected component from the container.

Abstract: The present disclosure relates to compounds of Formula (Ia) and (Ib): or a pharmaceutically acceptable salt thereof, which are useful in the treatment of an HIV infection in heavily treatment-experienced patients with multidrug resistant HIV infection.

Abstract: The present disclosure relates to generating and adjusting translated audio from a video-based source. The method includes receiving video data and corresponding audio data in a first language; generating a translated preliminary transcript in a second language; aligning timing windows of portions of the translated preliminary transcript with corresponding segments of the audio data; determining portions of the translated aligned transcript in the second language that exceed a timing window range of the corresponding segments of the audio data in the first language to generate flagged transcript portions; transmitting the original transcript, the translated aligned transcript, and the first speech dub to a first device, the generated flagged transcript portions included in the original transcript and the translated aligned transcript; receiving, from the first device, a modified original transcript; and generating, based on the modified original transcript, a second speech dub in the second language.