Abstract: A method of treating a subject having been diagnosed as having cancer with an immunotherapy is described. The method comprises targeting one or more clonal neoantigens selected using a method comprising determining whether a tumour-specific mutation is likely to be clonal in a subject. The method comprises providing sequence data from one or more samples from the subject comprising tumour genetic material, the sequence data comprising for each of the one or more samples, and determining the likelihood that the tumour-specific mutation is clonal as a posterior probability depending on: a prior probability of the mutation being clonal, and the probabilities of observing the sequence data if the tumour-specific mutation is (i) clonal and (ii) non-clonal, in view of a tumour fraction for each of the one or more samples and one or more candidate joint genotypes.

Abstract: In one embodiment, a method includes receiving, at a privacy transaction platform server, from a transaction network server, a transaction approval request associated with a user device and a requesting server including proffered transaction strings and proffered server properties associated with the requesting server, retrieving a privacy transaction record associated with the user device including tagged transaction strings and server properties associated with a provider server, determining that there is a transaction string match between the proffered transaction strings and the corresponding tagged transaction strings, determining that there is a server match between the requesting server and the provider server based on a validity metric for the transaction approval request exceeding a specified confidence threshold based on an analysis of the proffered server properties and the provider server properties, and transmitting, to the transaction network server, a validation response approving the requested

Abstract: Technologies for cloud-based secure WLAN group self-forming are described. One provisioner portal device receives, from a client provisionee device that desires to connect to a home WLAN, a first SSID and forwards, to a cloud service via a wireless AP device, the first SSID and a MAC address. The provisioner portal device receives, from the cloud service via the WAP device, a second SSID and a passphrase. The provisioner portal device sends, to the client provisionee device, a response that includes the second SSID. The provisioner portal device creates a one-time provisioning wireless network with the second SSID and the passphrase. Through the provisioner portal device, WAP credentials can be exchanged from the cloud server to the client provisionee device over a secure channel. The WAP credentials can be used to switch to the home WLAN without user interaction to manually enter the WAP credentials at the client provisionee device.

Abstract: In one embodiment, a method includes receiving, at a first server, from a privacy component on a user device, a privacy communication request including device data for the user device and server data for a second server communicating with the user device, generating a privacy communication response to be transmitted by the second server to a third server, the privacy communication response including a privacy communication string tagged to the second server and a privacy communication string record identifying the second server, transmitting, to the privacy component, the privacy communication string, receiving, from the third server, an approval request for a secure exchange associated with the privacy communication string, the approval request identifying a requesting server associated with the secure exchange, analyzing the approval request to determine whether there is a match between the requesting server and the second server, and transmitting, to the third server, a validation response.

Abstract: In one embodiment, a method includes receiving, from a user device, a first request for a privacy transaction card comprising a plurality of transaction metadata strings associated with a pending transaction between the user device and a first merchant server, analyzing, using a machine learning model, the transaction metadata strings in the first request to determine a risk assessment score for the first request, the machine learning model being trained to determine risk assessment scores based on multiple second requests stored in a privacy transaction database, determining whether the risk assessment score for the first request exceeds a specified risk threshold associated with the pending transaction, generating, upon determining the risk assessment score is below the specified risk threshold, a privacy transaction card comprising a unique privacy payment card number associated with the user device and the first merchant server, and transmitting, to the user device, the privacy transaction card.

Abstract: In one embodiment, a method includes receiving, at a privacy transaction server, from a user device, a privacy transaction card creation request including merchant metadata for a first merchant server, generating a privacy transaction card associated with an issuer server, storing, in a privacy transaction database, a privacy transaction card record for the privacy transaction card, including tagged card data identifying the first merchant server, transmitting, to the privacy component, the privacy transaction card, receiving, from the issuer server, a transaction approval request associated with the privacy payment card, the transaction approval request including transaction metadata identifying a second merchant server, retrieving the privacy transaction card record, analyzing the transaction metadata and the tagged card data to determine whether there is a match between the first merchant server and the second merchant server, and transmitting a transaction approval response indicating whether the transact

Abstract: Techniques for a server-based reconnection of disconnected devices in a network are described. In an example, a computer system receives, from a second device, first data of a first device. The first data indicates that the first device has disconnected from the network due a change in the password of the network. The computer system determines that the first device is authorized to connect to the network. Based on the first device being authorized, the computer system transmits a request for a token. The computer system compares the token to a token stored by the computer system. In response to the tokens matching, the computer system transmits second data to the first device via the second device. The second data includes an updated password of the network. The first device uses the second data to reestablish a connection with the network.

Abstract: Techniques for connecting computing devices to a network are described. For example, a network access device (NAD) connects to a first network that includes a first access point (AP). The NAD receives, from a computing device, first data identifying a second network to be established for the computing device and sends the first data to a server. The NAD receives back a first credential associated with access to the second network and sets up a second AP to the second network. The second AP is associated with the first credential. The NAD sends, to the computing device, second data indicating that access to the second network is available, generates a second credential associated with access to the first network via the first AP, and sends the second credential to the computing device via the second AP.

Abstract: This disclosure relates to methods and systems for automatically securing and validating multi-server electronic communications over a plurality of networks, without requiring additional physical or programmatic infrastructure on the intermediary servers. A processor-executable component can be transmitted from a first server to a compute device, where it generates a pair of asymmetric cryptographic parameters. The first server uses one of those parameters to verify subsequent communications from the component and respond with tagged privacy communication strings, which the component can provide to a second server as part of a secure communication exchange. The first server can then receive secure communication exchange approval request from a third server and analyze the request to determine a validity metric.

Abstract: Techniques for providing a server-based Wi-Fi Protected Setup (WPS) PIN procedure are described. In an example, a computing device generates a PIN associated with a WPS-PIN procedure. The computing device encrypts the PIN to generate an encrypted PIN based on a public key associated with a server. Further, the computing device sends, to another computing device that is communicatively coupled with the server via an access point, a WPS probe request that includes the encrypted PIN. Based on the WPS probe request, the computing device receives, from at least one of the other computing devices or the server, a credential associated with the access point. The computing devices connects to the access point based on the credential.

Abstract: A downhole system and method for producing and unloading from a well unloads a first fluid through a tubular in the well while blocking flow of a second fluid into the tubular. In an alternate mode, the second fluid is produced through the tubular while the first fluid is blocked from entering the tubular. In another alternate mode, a third fluid is unloaded through the tubular at the same the second fluid is produced from the well and through the tubular. In yet another alternate mode, the second fluid is pressurized downhole. In one example, the first fluid includes water, the second fluid includes a hydrocarbon gas, and the third fluid includes a hydrocarbon liquid. Means for unloading include a pump, means for pressurizing the second fluid include a compressor, and means for selectively blocking flow includes a flow circuit with one-way valves.

Abstract: This disclosure relates to methods and systems for automatically securing and validating multi-server electronic communications over a plurality of networks, without requiring additional physical or programmatic infrastructure on the intermediary servers. A processor-executable component can be transmitted from a first server to a compute device, where it generates a pair of asymmetric cryptographic parameters. The first server uses one of those parameters to verify subsequent communications from the component and respond with tagged privacy communication strings, which the component can provide to a second server as part of a secure communication exchange. The first server can then receive secure communication exchange approval request from a third server and analyze the request to determine a validity metric.

Abstract: This disclosure relates to methods and systems for automatically securing and validating multi-server electronic communications over a plurality of networks, without requiring additional physical or programmatic infrastructure on the intermediary servers. A processor-executable component can be transmitted from a first server to a compute device, where it generates a pair of asymmetric cryptographic parameters. The first server uses one of those parameters to verify subsequent communications from the component and respond with tagged privacy communication strings, which the component can provide to a second server as part of a secure communication exchange. The first server can then receive secure communication exchange approval request from a third server, and analyzes the request to determine a validity metric.

Abstract: A downhole system and method for producing and unloading from a well unloads a first fluid through a tubular in the well while blocking flow of a second fluid into the tubular. In an alternate mode, the second fluid is produced through the tubular while the first fluid is blocked from entering the tubular. In another alternate mode, a third fluid is unloaded through the tubular at the same the second fluid is produced from the well and through the tubular. In yet another alternate mode, the second fluid is pressurized downhole. In one example, the first fluid includes water, the second fluid includes a hydrocarbon gas, and the third fluid includes a hydrocarbon liquid. Means for unloading include a pump, means for pressurizing the second fluid include a compressor, and means for selectively blocking flow includes a flow circuit with one-way valves.

Abstract: A clamp for joining rods and a method for joining rods used for bracing a load is presented. The clamp has an opening to accept threaded portions of each of a pair of rods, which are parallel to each other with threads touching. The clamp forces the thread portions of the rods together to allow the rods to support compressive and tensile loads. The clamps may be used in pairs to provide added bending resistance to the rods.

Abstract: Techniques for providing a credential of a secure data network to a computing device are described. In an example, a system stores an association between the computing device and a user account. The user account is also associated with a credential of the secure data network. The system receives a certificate of the computing device and determines the association between the computing device and the user account based on the certificate. Further, the system authenticates the computing device based on the association being determined to send to the computing device data, where this data is verified based on a private key of the system. The system receives a request of the computing device for the credential based on the data and sends the credential to the computing device.

Abstract: Cable brace brackets and a system for bracing are provided. The cable brace bracket includes two hooks of different sizes and having a bracket angle between them that is less than 90°. The system using to cable brace brackets connected with a cable. One hook of each bracket is held against a surface using a threaded rod through the surface, and the other hook is interlocked with loops at the end of the cable.

Abstract: A system and method for remediation, curing concerns, and transferring information associated with declined transactions is disclosed. The present disclosure generally relates to receiving, by an application of a transaction account holder web client, a first passively pushed message, in response to a declined first attempt of a transaction request transmitting, by the transaction account holder web client, a response to the first passively pushed message; receiving, by an application of the transaction account holder web client, a second passively pushed message, in response to the response to the first passively pushed message meeting pre-established criteria; and transmitting, by the transaction account holder web client, a second attempt of the transaction request, wherein the second attempt is authorized.

Abstract: A method for cleaning a food waste recycling bin of a food waste recycling appliance includes maintaining between a lower portion and an upper portion of the food waste recycling bin a temperature differential sufficient such that water vapor is emitted from waste located in the lower portion of the food waste recycling bin.

Abstract: A method for cleaning a food waste recycling bin of a food waste recycling appliance includes maintaining between a lower portion and an upper portion of the food waste recycling bin a temperature differential sufficient such that water vapor is emitted from waste located in the lower portion of the food waste recycling bin.