Patents by Inventor Andrew Tsotinis

Andrew Tsotinis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GABAmodulating neurosteroids
    Patent number: 7064116
    Abstract: The present invention relates to novel steroid derivatives that ace on the gamma-aminobutyric acid receptor-chloride ionophore (GR) complex as well as methods for making the same and their applications to induce anesthesia, in the treatment of stress, anxiety, PMS, PND, and seizures such as those caused by epilepsy, to ameliorate or prevent the attacks of anxiety, muscle tension, and depression common with patients suffering from central nervous system abnormalities. The present invention comprises a compound represented by Formula (I): wherein, R, R1, R2, R3, R4, R5 are defined in the description of the invention. The present invention also includes formulations which consist of one or more of the compounds of Formula (I).
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: June 20, 2006
    Inventors: Theodora Calogeropoulou, Andrew Tsotinis, Charikleia Souli, Alexandros Makriyannis
  • GABA a modulating neurosteroids
    Publication number: 20050176976
    Abstract: The present invention relates to novel steroid derivatives that ace on the gamma-aminobutyric acid receptor-chloride ionophore (GR) complex as well as methods for making the same and their applications to induce anesthesia, in the treatment of stress, anxiety, PMS, PND, and seizures such as those caused by epilepsy, to ameliorate or prevent the attacks of anxiety, muscle tension, and depression common with patients suffering from central nervous system abnormalities. The present invention comprises a compound represented by Formula (I): wherein, R, R1, R2, R3, R4, R5 are defined in the description of the invention. The present invention also includes formulations which consist of one or more of the compounds of Formula (I).
    Type: Application
    Filed: December 21, 2001
    Publication date: August 11, 2005
    Inventors: Theodora Calogeropoulou, Andrew Tsotinis, Charikleia Souli, Alexandros Makriyannis