Patents by Inventor Andrew Vila

Andrew Vila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240024481
    Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.
    Type: Application
    Filed: October 3, 2023
    Publication date: January 25, 2024
    Inventors: Leo PAVLIV, Andrew VILA
  • Patent number: 11806400
    Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: November 7, 2023
    Assignee: Cumberland Pharmaceuticals Inc.
    Inventors: Leo Pavliv, Andrew Vila
  • Publication number: 20220401360
    Abstract: Embodiments of the present invention include inhalable composition, comprising milrinone or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable carrier, an excipient, a surfactant; the composition being capable of being administered by inhalation.
    Type: Application
    Filed: August 16, 2022
    Publication date: December 22, 2022
    Inventors: Nicholas A. Haglund, Zachary Cox, Leo Pavliv, Andrew Vila
  • Publication number: 20220233473
    Abstract: A ready-to-administer stable injectable norepinephrine solution comprising water, norepinephrine, and a tonicity agent. The solution has a pH from 3.7 to 4.3 and is substantially free of chelating agents and antioxidants.
    Type: Application
    Filed: January 26, 2022
    Publication date: July 28, 2022
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Andrew VILA
  • Publication number: 20210106561
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Application
    Filed: October 23, 2020
    Publication date: April 15, 2021
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo Pavliv, Andrew Vila
  • Publication number: 20200316022
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Application
    Filed: June 29, 2020
    Publication date: October 8, 2020
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Andrew Vila
  • Publication number: 20200261581
    Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.
    Type: Application
    Filed: May 7, 2020
    Publication date: August 20, 2020
    Inventors: Leo PAVLIV, Andrew VILA
  • Publication number: 20190142944
    Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.
    Type: Application
    Filed: January 16, 2019
    Publication date: May 16, 2019
    Inventors: Leo PAVLIV, Andrew VILA
  • Publication number: 20190117621
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Application
    Filed: December 21, 2018
    Publication date: April 25, 2019
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Andrew Vila
  • Publication number: 20180344693
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Application
    Filed: August 13, 2018
    Publication date: December 6, 2018
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Andrew Vila
  • Publication number: 20180036282
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Application
    Filed: October 20, 2017
    Publication date: February 8, 2018
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo Pavliv, Andrew Vila
  • Publication number: 20180028440
    Abstract: Embodiments of the present invention include inhalable composition, comprising milrinone or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable carrier, an excipient, a surfactant; the composition being capable of being administered by inhalation.
    Type: Application
    Filed: February 16, 2016
    Publication date: February 1, 2018
    Inventors: Nicholas A. Haglund, Zachary Cox, Leo Pavliv, Andrew Vila
  • Patent number: 9820966
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: November 21, 2017
    Assignee: CUMBERLAND PHARMACEUTICALS
    Inventors: Leo Pavliv, Andrew Vila
  • Publication number: 20160128977
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Application
    Filed: November 11, 2014
    Publication date: May 12, 2016
    Inventors: Leo PAVLIV, Andrew VILA
  • Publication number: 20150335747
    Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.
    Type: Application
    Filed: June 30, 2015
    Publication date: November 26, 2015
    Inventors: Leo PAVLIV, Andrew VILA
  • Patent number: 9072710
    Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: July 7, 2015
    Assignee: Cumberland Pharmaceuticals Inc.
    Inventors: Leo Pavliv, Andrew Vila
  • Patent number: 9072661
    Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: July 7, 2015
    Assignee: Cumberland Pharmaceuticals Inc.
    Inventors: Leo Pavliv, Andrew Vila
  • Publication number: 20150065553
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Application
    Filed: November 11, 2014
    Publication date: March 5, 2015
    Inventors: Leo PAVLIV, Andrew VILA
  • Patent number: 8933115
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: January 13, 2015
    Assignee: Cumberland Pharmaceuticals Inc.
    Inventors: Leo Pavliv, Andrew Vila
  • Publication number: 20130245120
    Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.
    Type: Application
    Filed: March 16, 2012
    Publication date: September 19, 2013
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo Pavliv, Andrew Vila