Abstract: A computer-implemented method for detecting suspicious files may include (1) detecting a file within incoming file traffic directed to a file recipient, (2) identifying a type of the file within the incoming file traffic directed to the file recipient, (3) determining a frequency with which the type of the file appears within the incoming file traffic directed to the file recipient, and (4) performing a security action on the file in response to the frequency of the type of the file within the incoming file traffic falling below a predetermined threshold. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with materials which generate identifiable spectra, a plurality of beads may be identified within the fluid. Reading of the beads is facilitated by restraining the beads in arrays, and/or using a focused laser.

Abstract: Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with materials which generate identifiable spectra, a plurality of beads may be identified within the fluid. Reading of the beads is facilitated by restraining the beads in arrays, and/or using a focused laser.

Abstract: The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The present invention also provides methods of obtaining a quantitative score for a patient with kidney cancer based on measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The genes may be grouped into functional gene subsets for calculating the quantitative score and the gene subsets may be weighted according to their contribution to cancer recurrence.

Abstract: Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with materials which generate identifiable spectra, a plurality of beads may be identified within the fluid. Reading of the beads is facilitated by restraining the beads in arrays, and/or using a focused laser.

Abstract: Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with materials which generate identifiable spectra, a plurality of beads may be identified within the fluid. Reading of the beads is facilitated by restraining the beads in arrays, and/or using a focused laser.

Abstract: The invention provides methods for sequencing and sample preparation for sequencing and amplification.

Abstract: The invention provides barcode libraries and methods of making and using them including obtaining a plurality of nucleic acid constructs in which each construct comprises a unique N-mer and a functional N-mer and segregating the constructs into a fluid compartments such that each compartment contains one or more copies of a unique construct. The invention further provides methods for digital PCR and for use of barcode libraries in digital PCR.

Abstract: Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with materials which generate identifiable spectra, a plurality of beads may be identified within the fluid. Reading of the beads is facilitated by restraining the beads in arrays, and/or using a focused laser.

Abstract: A method and product for producing a soft sounding aerosol spray from a particulate suspension, said method and product involving a spray channel having an exit orifice of internal diameter of from 0.5 to 0.8 mm and a terminal section leading to the exit orifice of internal diameter from 0.5 to 0.8 mm for a length of 5 mm or greater, the terminal section of the spray channel including the exit orifice having a tubular internal surface free from obstacle.

Abstract: Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with materials which generate identifiable spectra, a plurality of beads may be identified within the fluid. Reading of the beads is facilitated by restraining the beads in arrays, and/or using a focused laser.

Abstract: Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with materials which generate identifiable spectra, a plurality of beads may be identified within the fluid. Reading of the beads is facilitated by restraining the beads in arrays, and/or using a focused laser.

Abstract: The invention generally relates to method for screening for a condition in a subject. In certain embodiments, methods of the invention involve obtaining a pool of nucleic acids from a sample, incubating the nucleic acids with first and second sets of binders, in which the first set binds uniquely to different regions of a target nucleic acid in the pool, the second set binds uniquely to different regions of a reference nucleic acid in the pool, and the first and second sets include different detectable labels, removing unbound binders, detecting the labels, and screening for a condition based upon results of the detecting step.

Abstract: The concepts relate to data handling, and more specifically to data handling scenarios where data is revised on one computer and stored on another computer. One example can obtain a set of blobs relating to revisions of a file. The example can determine a target size of datastore blobs. In an instance where a total size of the set of blobs is less than the target size, this example can aggregate the set of blobs into an individual datastore blob. Otherwise, the example can identify new or edited individual blobs of the set and aggregate the new or edited individual blobs into first datastore blobs. The example can also aggregate other individual blobs of the set into second datastore blobs.

Abstract: In a prosthetic ankle joint, a first component has a lower articular bearing surface and is configured for connection to the distal end of the tibia such that the lower articular bearing surface is remote from the tibia. A second component has an upper articular bearing surface and is configured for connection to the tarsal bone such that the upper articular bearing surface is remote from the tarsal bone. A third component is interposed between the first and second component and has an upper bearing surface configured to be slidable on the lower bearing surface of the first component and a lower bearing surface configured to be slidable on the upper surface of the second component. At at least one of the components and/or bearing surfaces is configured to allow the third component to be slidable in an anterior/posterior direction but to prevent the third component being slidable in a medial/lateral direction.

Abstract: A map interface presents a geographic map with markers identifying geographic locations associated with content items. When the geographic distance between two or more content items is less than a threshold distance, multiple content items are grouped to create an aggregated content item. Based on the geographic locations associated with the grouped content items, a geographic location is associated with the aggregated content item. A single marker identifies the geographic location for the aggregated content item on the geographic map. When a user viewing the map interface accesses the single marker, content selected from the content items combined to generated the aggregated content item is presented as well as the geographic location associated with the aggregated content item.

Abstract: A map interface presents a geographic map with markers identifying geographic locations associated with content items. When the geographic distance between two or more content items is less than a threshold distance, multiple content items are grouped to create an aggregated content item. Based on the geographic locations associated with the grouped content items, a geographic location is associated with the aggregated content item. A single marker identifies the geographic location for the aggregated content item on the geographic map. When a user viewing the map interface accesses the single marker, content selected from the content items combined to generated the aggregated content item is presented as well as the geographic location associated with the aggregated content item.

Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.

Abstract: A social graph may be modeled as a collection of claims. Each claim is associated with an author, an audience, and an assertion about a fact. Probabilistic information may be collected from various sources for a claim, enabling a social networking system to evaluate a truthfulness of the assertion made in the claim. User-declared profile information may be evaluated as claims. A user, entity, or application may make claims about any assertions made in the social networking system. Reputation scores may be determined for users based on evaluations of their historical assertions. Claims may be evaluated for truthfulness using a probabilistic prediction model using heuristics analysis, regression analysis, and machine learning methods. A claims-based profile of users may be provided to viewers based on the contexts in which the claims were made. Viewers may view claims made about users, such as the users' biographical information, contact information, expertise, and interests.

Abstract: A social graph may be modeled as a collection of claims. Each claim is associated with an author, an audience, and an assertion about a fact. Probabilistic information may be collected from various sources for a claim, enabling a social networking system to evaluate a truthfulness of the assertion made in the claim. User-declared profile information may be evaluated as claims. A user, entity, or application may make claims about any assertions made in the social networking system. Reputation scores may be determined for users based on evaluations of their historical assertions. Claims may be evaluated for truthfulness using a probabilistic prediction model using heuristics analysis, regression analysis, and machine learning methods. A claims-based profile of users may be provided to viewers based on the contexts in which the claims were made. Viewers may view claims made about users, such as the users' biographical information, contact information, expertise, and interests.