Abstract: A series of substituted benzimidazole, imidazo[1,2-a]pyridine and pyrazolo[1,5-a]pyridine derivatives, and analogues thereof, being potent modulators of human TNF? activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.

Abstract: A series of substituted benzimidazole, imidazo[1,2-a]pyridine and pyrazolo[1,5-a]pyridine derivatives, and analogues thereof, being potent modulators of human TNF? activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.

Abstract: A computer is disclosed comprising a processor able to support multithreading and concurrently programmed in at least two threads with respective GPS signal processing programs which are each capable of processing GPS signal samples outputted from the same source.

Abstract: A method of generating a spray comprising subjecting a liquid on a continuous atomisation surface (1) to acoustic vibration, characterised in that the continuous atomisation surface (1) comprises multiple hollows from which the liquid is atomised.

Abstract: A GPS receiver (10) is disclosed comprising a GPS antenna and a GPS RF front-end including an analogue to digital converter for sampling received GPS signals; and a processor for outputting, including to an external device, the GPS signal samples together with ancillary information either directly or indirectly describing characteristics of the GPS signal samples and/or the GPS signals contained therein. Also disclosed is a corresponding method of providing a position fix and a computer program, computer-readable storage medium and apparatus for the same.

Abstract: A method of acquiring a received spread spectrum signal, especially a GPS signal, is disclosed together with a spread spectrum signal receiver and a cellular telephone incorporating such a receiver. The method comprises the steps of: providing a replica signal containing a pseudorandom noise code, corresponding to that of the spread spectrum signal; providing a subject signal containing two fragments of the spread spectrum signal initially received during respective time periods between which a further time period elapses; and coherently correlating the replica signal with the subject signal over the two fragments.

Abstract: A method of appending a position stamp to an image file of a photo or video clip taken with a digital camera having a GPS antenna and a GPS RF front-end including an analogue to digital converter for receiving GPS signals and outputting GPS signal samples together with a digital camera and computer for the same. The method comprising the steps of: (i) upon a user taking a photo or video clip: (a) creating an image file containing that photo or video clip, and (b) sampling received GPS signals and storing those GPS signal samples with an indication of the image file of the photo or video clip to which those GPS signal samples pertain; and (ii) subsequently processing the GPS signal samples to obtain a position fix and appending the position fix to the image file.

Abstract: A method of correlating a sampled direct sequence spread spectrum signal with a locally provided replica signal containing a spreading code is disclosed together with a corresponding signal processor, receiver, computer-readable storage medium and computer program for the same. The method comprises the steps of combining the bit or bits of at least two signal samples of the received signal to form a first word; providing a second word containing bits corresponding to the replica signal; and executing one or more software based instructions to process the first and second words, especially in hardwired circuitry, in order to obtain a correlation value.

Abstract: In accordance with the present invention, a method of processing a sampled signal stream containing at least one spread spectrum signal is provided together with a receiver, computer, computer-readable storage medium and computer program for the same. The method comprises the steps of processing samples at a first bit level and, either in parallel or subsequently, processing samples at a second bit level, different from the first bit level.

Abstract: A method of generating a map display for a graphical user interface (GUI) comprising the steps of displaying a map, highlighting a first area on the map surrounding a first position fix wherein the size of the area corresponds to the accuracy of the first position fix and highlighting a second area on the map surrounding a second position fix wherein the size of the second area corresponds to the accuracy of the second position fix. Either (a) when the first and second areas overlap, either (i) the one corresponding to the most recent or accurate position fix is displayed on top of the other or (ii) the highlighting of the overlapping area is different from that of those parts of the first and second areas which do not overlap, or (b) the manner in which at least one of the position fixes is obtained is indicated by the colour of the highlight. The area highlighted on the map surrounding the position fix may be a shape other than a circle.

Abstract: A GPS receiver device is disclosed comprising a GPS antenna and a GPS RF front-end including an analogue to digital converter for receiving GPS signals and outputting GPS signal samples; and a processor for encrypting the GPS signal samples and transmitting the encrypted GPS signal samples to an external device. Also disclosed is a corresponding method of providing a position fix comprising the steps of connecting to a GPS receiver device and receiving encrypted GPS signal samples therefrom, decrypting the encrypted GPS signal samples and processing the decrypted GPS signal samples to determine a position fix; and a computer program, computer-readable storage medium and apparatus for the same.

Abstract: A GPS receiver is disclosed which has an omnidirectional antenna and a directional antenna and is configured to (i) acquire a first GPS signal from the output of the directional antenna, either alone or combined with the output of the omnidirectional antenna, and (ii) acquire a second GPS signal from the output of the omnidirectional antenna alone. Also, disclosed is a GPS receiver having an omnidirectional antenna and a directional antenna which is configured to acquire a GPS signal from the output of the directional antenna alone.

Abstract: A nozzle arrangement which is suitable for use in the generation of a spray or aerosol and which is adapted for connection to a fluid supply, the nozzle arrangement including a fluid inlet through which fluid enters the arrangement from the fluid supply and fluid outlet through which the fluid is ejected from the nozzle arrangement, fluid inlet and fluid outlet being connected to a fluid flow passage through which, in use, fluid flows from the inlet to the outlet, wherein the nozzle arrangement includes control means provided in the passage which, in use, acts to modify the flow characteristics of the fluid in the fluid flow passage to effectively control fluid droplet size produced in the spray or aerosol by the nozzle arrangement.

Abstract: A method of despreading GPS spread spectrum signals containing pseudorandom noise (PRN) code sequences and received by a GPS receiver (24) is disclosed together with a GPS receiver (24) and a mobile communications device (MS1) (especially a mobile cellular telephone) for the same. The method comprises the steps of providing Doppler information relating to an estimate of the variation in Doppler shift as observed on the target signal by the GPS receiver and which is attributable to the motion of the GPS satellite; and correlating the target signal with a reference signal containing corresponding PRN code sequences, wherein, in the course of a single dwell, the correlation is modified as a function of the Doppler information.

Abstract: A nozzle arrangement which is suitable for use in the generation of a spray or aerosol and which is adapted for connection to a fluid supply, the nozzle arrangement including a fluid inlet through which fluid enters the arrangement from the fluid supply and fluid outlet through which the fluid is ejected from the nozzle arrangement, fluid inlet and fluid outlet being connected to a fluid flow passage through which, in use, fluid flows from the inlet to the outlet, wherein the nozzle arrangement includes control means provided in the passage which, in use, acts to modify the flow characteristics of the fluid in the fluid flow passage to effectively control fluid droplet size produced in the spray or aerosol by the nozzle arrangement.