Patents by Inventor Andrzej DZIEMBOWSKI

Andrzej DZIEMBOWSKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for selection of hDIS3 PIN domain inhibitors and use of hDIS3 PIN domain inhibitors for cancer treatment
    Patent number: 9611514
    Abstract: The present invention relates to a method for selection or screening of hDIS3 PIN domain inhibitors, yeast strain and cell line used in such methods It also relates to new therapeutic agents selected hDIS3 PIN domain inhibitors and uses thereof in the treatment of cancers having mutations inhDIS3 RNB domain, especially multiple myeloma. The invention also relates to composition comprising new therapeutic agent hDIS3 PIN domain inhibitor and method for inducing synthetic lethality in a cancer cell.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: April 4, 2017
    Assignees: INSTYTUT BIOCHEMII I BIOFIZYKI POLSKIEJ AKADEMII NAUK, ONCOARENDI THERAPEUTICS SP ZOO, MIEDZYNARODOWY INSTYTUT BIOLOGII MOLEKULARNEJ I KOMORKOWEJ W WARSZAWIE
    Inventors: Andrzej Dziembowski, Rafal Tomecki, Karolina Drazkowska, Roman Szczesny, Krystian Stodus, Weronika Jonko, Marcin Nowotny, Adam Golebiowski, Jacek Olczak
  • Method for selection of hDIS3 PIN domain inhibitors and use of hDIS3 PIN domain inhibitors for cancer treatment
    Publication number: 20160090639
    Abstract: The present invention relates to a method for selection or screening of hDIS3 PIN domain inhibitors, yeast strain and cell line used in such methods It also relates to new therapeutic agents selected hDIS3 PIN domain inhibitors and uses thereof in the treatment of cancers having mutations inhDIS3 RNB domain, especially multiple myeloma. The invention also relates to composition comprising new therapeutic agent hDIS3 PIN domain inhibitor and method for inducing synthetic lethality in a cancer cell.
    Type: Application
    Filed: May 20, 2014
    Publication date: March 31, 2016
    Inventors: Andrzej DZIEMBOWSKI, Rafal TOMECKI, Karolina DRAZKOWSKA, Roman SZCZESNY, Krystian STODUS, Weronika JONKO, Marcin NOWOTNY, Adam GOLEBIOWSKI, Jacek OLCZAK