Abstract: A patient's skin puncturing device comprises a body (1), inside of which a puncturing needle (4) and at least one turned down arm (5, 6) are guided, and a push button (2). Between body (1) and button (2) activating elements (10, 11, 12, 13) are placed. Activating elements enable push button (2) to be forced into body (1) when a pre-set thrust force is exceeded. Needle (4) is driven by push button (2) by a membrane (9), which is broken after resting the needle (4) upon an abutting surface (16) in body (1). After breaking membrane (9) and the patient's skin puncture by the needle (4), needle (4) is withdrawn inwards the body (1) due to a transfer of a thrust force from push button (2) by turned down arm (5, 6) guided in the body (1).

Abstract: A patient's skin puncturing device according to the present invention is built of a body and of seated therein a pricking needle assembly and of a push-button arranged in the upper portion of the body. Between the push-button and the pricking needle assembly at least two driving springs are arranged. The driving springs are connected by upper ends with the push-button provided with a pushing face. Between the body and the pricking needle assembly at least two return springs are disposed, which are connected with the body. The pricking needle assembly has a driving face cooperating with the pushing face of the push-button, and in the upper portion has wings which upper surfaces cooperate with the driving springs of the push-button and which lower surfaces cooperate with the return springs, and has outer projections cooperating with inner projections with which the body is provided.

Abstract: A patient's skin puncturing device, particularly for collecting a blood sample for diagnostic purposes, including a housing, a lancet slidably positioned inside the housing and having a body with a sheathed puncturing needle seated therein, and a push button positioned at the one end of the housing. Between a face end of the push button and the lancet body a drive spring is placed, and between the other end of the housing, which is provided with an opening for the puncturing needle, and the lancet body a return spring is placed. Between the housing and the lancet body is placed a lancet actuation lock, preferably in the form of interlocks of a washer. The device has a drive spring catch, preferably in the form of grabs of the washer, to preclude the drive spring from following the lancet in the puncture phase and in the retraction phase of the lancet.

Abstract: The device comprises a body (2) and placed therein a needle assembly (1) and a push button (3) located in the upper portion of the body (2), whereas the needle assembly (1) has in its lower portion a sheathed piercing needle (5), and the push button (3) has in its upper portion a press surface, and between the body (2) and the needle assembly (1) a return spring (27) is placed. The push button (3) is coupled with the needle assembly (1) by means of abutting surface elements (15, 44), whereas during the movement of the push button (3) and after resting the needle assembly (1) on the element (20) of the body (2) and after performing the full-depth piercing, one of the abutting surface elements (15, 44) bends, releasing the needle assembly (1) from the thrust of the push button (3), whereupon the needle assembly (1) retracts to the inside of the body by means of the return spring (27).

Abstract: A patient's skin puncturing device according to the present invention is built of a body (1) and of seated therein a pricking needle assembly (3) and of a push-button (5) arranged in the upper portion of the body (1). Between the push-button (5) and the pricking needle assembly (3) at least two driving springs (9) are arranged. The driving springs (9) are connected by upper ends with the push-button (5) provided with a pushing face (8). Between the body (1) and the pricking needle assembly (3) at least two return springs (30) are disposed, which are connected with the body (1). The pricking needle assembly (3) has a driving face (24) cooperating with the pushing face (8) of the push-button (5), and in the upper portion has wings (12) which upper surfaces cooperate with the driving springs (9) of the push-button (5) and which lower surfaces cooperate with the return springs (30), and has outer projections (17) cooperating with inner projections (18) with which the body (1) is provided.

Abstract: A patient's skin puncturing device, particularly for collecting a blood sample for diagnostic purposes, comprises a housing (1), a lancet slidably positioned inside the housing (1) and having a body (3) with a sheathed puncturing needle (4) seated therein, and a push button (2) positioned at the one end of the housing (1). Between a face end of the push button (2) and the lancet body (3) a drive spring (5) is placed, and between the other end of the housing (1), which is provided with an opening (Ia) for the puncturing needle (4), and the lancet body (3) a return spring (7) is placed. Between the housing (1) and the lancet body (3) is placed lancet actuation locking means, preferably in the form of interlocks (6b) of a washer (6). The device has drive spring catching means, preferably in the form of grabs (6a) of the washer (6), to preclude the drive spring (5) from following the lancet in the puncture phase and in the retraction phase of the lancet.

Abstract: Lancet, in particular for a patient's skin puncturing device for collecting a blood sample for diagnostic purposes, is comprised of the body (1) made of plastic material, in which the needle (2) is coaxially fixed. the tip (3) of the needle (2) is covered by the sheath (4) moulded together with the body (1) and breakably connected therewith. The lancet has additional coaxial with the body (1) and the sheath (4) the guiding member, which is slidably mounted on the guiding member, which is slidably mounted on the guiding segment (5) of the body (1) and is immovably affixed to the sheath (4). The lancet, according to the present invention, insures the required sterility of the tip (3) of the needle (2) and, simultaneously, precludes the tip (3), in particular, in case of the needle of small diameter, from damage during the removal of the sheath (4) from the needle tip (3) before use of the lancet.

Abstract: The device comprises a body (2) and placed therein a needle assembly (1) and a push button (3) located in the upper portion of the body (2), whereas the needle assembly (1) has in its lower portion a sheathed piercing needle (5), and the push button (3) has in its upper portion a press surface, and between the body (2) and the needle assembly (1) a return spring (27) is placed. The push button (3) is coupled with the needle assembly (1) by means of abutting surface elements (15, 44), whereas during the movement of the push button (3) and after resting the needle assembly (1) on the element (20) of the body (2) and after performing the full-depth piercing, one of the abutting surface elements (15, 44) bends, releasing the needle assembly (1) from the thrust of the push button (3), whereupon the needle assembly (1) retracts to the inside of the body by means of the return spring (27).

Abstract: A pipetting device comprises a housing (1) with a handle (2) and a pipette (4) holder assembly (3), wherein the housing (1) end portion (7) incorporates a spherical raceway (16) to which the pipette (4) holding assembly (3) in mounted by the means of a connecting assembly (17) capable of sliding on the spherical raceway (16) at the housing (1) end portion (7) to facilitate the change of orientation angle of the pipette (4) axle in every plane with respect to the handle (2). The connecting assembly (17) comprises a first slider (18) slidably set in a rectangular opening (19) in the spherical raceway (16) at the housing (1) end portion (7), and a second slider (20) slidably set in a rectangular opening (21) in the first slider (18).

Abstract: A Patient's skin puncturing device comprises a body (1), inside of which a puncturing needle (4) and at least one turned down arm (5, 6) are guided, and a push button (2), whereas between said body (1) and said button (2) activating elements (10, 11, 12, 13) are placed, said activating elements (10, 11, 12, 13) enable to force said push button (2) into said body (1) when pre-set thrust force is exceeded. The puncturing needle (4) is driven by said push button (2) by means of a membrane (9), which is broken after resting the puncturing needle (4) upon an abutting surface (16) in said body (1). After breaking the membrane (9) and the patient's skin puncture by the puncturing needle (4), the puncture by the needle (4) is withdrawn inwards the body (1) due to a transfer of a thrust force from the push button (2) by said turned down arm (5, 6) guided in the body (1).

Abstract: An electronic pipetting device for aspirating and dispensing of set liquid volume comprises a handle (1), to the lower part of which a stem assembly (3) is attached, and a control panel (2), whereas the control panel (2) is connected with the handle (1) in such a way that it can rotate with respect to the longitudinal axis of the handle (1) and/or move it upwards and parallel to the longitudinal axis of the handle (1).

Abstract: A method for capturing activated receptor signaling complexes from live cells, utilizing bead based biology wherein live cells are contacted with ligand coated beads to form bead binding sites and thereby initiating formation of a ligand-receptor complex at said bead binding site; and a process for distinguishing and confirming non-specifically bound proteins from specifically bound receptor complexes by utilization of one or more methods of biochemical or biophysical analysis, thereby providing, in a preferred embodiment, a utilization of confocal microscopy and proteomic mass spectroscopy.

Abstract: A pipetting device comprises a housing (1) with a handle (2) and a pipette (4) holder assembly (3), wherein the housing (1) end portion (7) incorporates a spherical raceway (16) to which the pipette (4) holding assembly (3) in mounted by the means of a connecting assembly (17) capable of sliding on the spherical raceway (16) at the housing (1) end portion (7) to facilitate the change of orientation angle of the pipette (4) axle in every plane with respect to the handle (2). The connecting assembly (17) comprises a first slider (18) slidably set in a rectangular opening (19) in the spherical raceway (16) at the housing (1) end portion (7), and a second slider (20) slidably set in a rectangular opening (21) in the first slider (18).

Abstract: In the method of dispensing liquid according to the invention, when liquid is aspired by the pump to the pipette, the required size of dose of the liquid is dispensed from the pipette in proportion to the atmospheric air fed thereto through a valve or a set of connected to the pipette, whereas the amount of supplied atmospheric air is processor programmed by the determination of time and/or flow rate and/or damping of the supply of atmospheric air into the pipette. Pipetting device according to the invenvention comprises a housing with a handle (3) for mounting the pipette (4), whereas in the housing, an air pump (6) is located, connected to the pipette (5), and a processor (15) to control the operation of the device. The pipetting device comprises also a set of valves (10) for processor (15) controlled atmospheric airflow during dispensing liquid, whereas the set of valves (10) is connected to the pipette (5).

Abstract: In the method of pipette calibration, the volume of liquid to be aspired is manually set by turning in and out the adjustment screw regulating the length of the operational stroke of the plunger inside the shaft, the position of the adjustment screw is detected, and a signal corresponding to the position of the adjustment screw is sent to the pipette electronic system, and next the signal corresponding to the position of the adjustment screw is compared with values of points from the aspiration table or values of the aspiration function, which has been earlier input to the memory of the electronic system correspondingly as the standard aspiration table or aspiration function for the pipette, and next to the position of the adjustment screw, the value of the aspired liquid volume is assigned, and displayed on the display.

Abstract: Pipette tip container comprises a base for setting a tray (19) with tips (21) and a cover being a tray feeder (2), wherein two opposite elastic side walls of the feeder (2) have on their inner side wedge-shaped projections (31, 32) for the tray (19) with tips (21).

Abstract: A system and method for searching documents in a data source and more particularly, to a system and method for analyzing and clustering of documents for a search engine. The system and method includes analyzing and processing documents to secure the infrastructure and standards for optimal document processing. By incorporating Computational Intelligence (CI) and statistical methods, the document information is analyzed and clustered using novel techniques for knowledge extraction. A comprehensive dictionary is built based on the keywords identified by the these techniques from the entire text of the document. The text is parsed for keywords or the number of its occurrences and the context in which the word appears in the documents. The whole document is identified by the knowledge that is represented in its contents. Based on such knowledge extracted from all the documents, the documents are clustered into meaningful groups in a catalog tree.

Abstract: A method and system for searching a document source. The method includes analyzing a query and then creating a query pattern. A document is search in a document source which match the query pattern. The retrieved documents are divided into subsets of similar documents, where each subset of the subsets of similar documents is described in terms of a subset pattern. An ordered list of clusters based on the subset pattern of each subset of similar documents is then retrieved. The ordered list of clusters includes separate clusters which contain similar documents retrieved in response to the query. A machine readable medium containing code for searching a document source is also provided.