Patents by Inventor Andrzej Myc
Andrzej Myc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220031826Abstract: The present invention relates to a veterinary vaccine containing nanoadjuvants in the form of emulsion and Clostridium difficile antigens, as well as the use of the vaccine in the preventions and treatment of a C. difficile infection, especially in birds and mammals. The object of the invention is also the use of this vaccine to produce C. difficile-specific antibodies.Type: ApplicationFiled: December 3, 2019Publication date: February 3, 2022Inventors: Andrzej Myc, Agnieszka Razim, Sabina Gorska, Andrzej Gamian
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Patent number: 11116825Abstract: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides nanoemulsion compositions and methods of using the same for the induction of immune responses (e.g., innate and adaptive immune responses (e.g., for generation of host immunity against an environmental pathogen)). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.Type: GrantFiled: May 21, 2018Date of Patent: September 14, 2021Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Andrzej Myc, Ilona Kryczek, James R. Baker, Jr.
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Publication number: 20190022200Abstract: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides nanoemulsion compositions and methods of using the same for the induction of immune responses (e.g., innate and adaptive immune responses (e.g., for generation of host immunity against an environmental pathogen)). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.Type: ApplicationFiled: May 21, 2018Publication date: January 24, 2019Inventors: Andrzej Myc, Ilona Kryczek, James R. Baker, JR.
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Patent number: 10138279Abstract: The present invention relates to methods and compositions for stimulating an immune response. Specifically, the present invention provides methods of inducing an immune response to bacteria of the genus Bacillus (e.g., Bacillus anthracis) in a subject (e.g., a human subject) and compositions useful in such methods (e.g., a nanoemulsion comprising Bacillus anthracis or an immunogenic portion thereof). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination) and research applications.Type: GrantFiled: April 13, 2007Date of Patent: November 27, 2018Assignee: Regents of the University of MichiganInventors: James R. Baker, Jr., Anna Bielinska, Andrzej Myc
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Patent number: 9974844Abstract: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides nanoemulsion compositions and methods of using the same for the induction of immune responses (e.g., innate and adaptive immune responses (e.g., for generation of host immunity against an environmental pathogen)). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.Type: GrantFiled: November 17, 2009Date of Patent: May 22, 2018Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Andrzej Myc, Ilona Kryczek, James R. Baker, Jr.
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Patent number: 9839685Abstract: The present invention relates to methods and compositions for the stimulation of immune responses. Specifically, the present invention provides methods of inducing an immune response to human immunodeficiency virus (HIV) in a subject (e.g., a human subject) and compositions useful in such methods (e.g., a nanoemulsion comprising HIV or antigenic portion thereof).Type: GrantFiled: April 13, 2007Date of Patent: December 12, 2017Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGANInventors: James R. Baker, Jr., Anna Bielinska, Andrzej Myc
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Publication number: 20150306238Abstract: The present invention relates to bacteria-targeting nanoparticles and related methods of use. In particular, the present invention relates to dendrimer nanoparticles conjugated with Vancomycin and/or Polymixin (e.g., Polymixin B, Polymixin E). In certain embodiments, such dendrimer nanoparticles are used to sequester and/or identify bacteria (e.g., Gram-positive bacteria and/or Gram-negative bacteria), screen liquid samples (e.g., water samples, food samples, pharmaceutical samples, blood samples, blood platelet samples, etc.) for the presence of bacteria (e.g., Gram-positive bacteria and/or Gram-negative bacteria), treat disorders associated with bacteria (e.g., Gram-positive bacteria and/or Gram-negative bacteria), and/or identify, sequester, and remove bacteria (e.g., Gram-positive bacteria and/or Gram-negative bacteria) from a liquid sample (e.g., water sample, food sample, pharmaceutical sample, blood sample, blood platelet sample, etc.).Type: ApplicationFiled: November 27, 2013Publication date: October 29, 2015Inventors: James R. Baker, Seok Ki Choi, Andrzej Myc
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Publication number: 20150266933Abstract: The present invention relates to methods and compositions for stimulating an immune response. Specifically, the present invention provides methods of inducing an immune response to bacteria of the genus Bacillus (e.g., Bacillus anthracis) in a subject (e.g., a human subject) and compositions useful in such methods (e.g., a nanoemulsion comprising Bacillus anthracis or an immunogenic portion thereof). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination) and research applications.Type: ApplicationFiled: April 13, 2007Publication date: September 24, 2015Applicant: Regents of the University of MichiganInventors: James R. Baker, JR., Anna Bielinska, Andrzej Myc
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Patent number: 8771731Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.Type: GrantFiled: August 18, 2006Date of Patent: July 8, 2014Assignee: The Regents of the University of MichiganInventors: James R. Baker, Jr., Tarek Hamouda, Amy Shih, Andrzej Myc
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Publication number: 20130273113Abstract: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides nanoemulsion compositions and methods of using the same for the induction of immune responses (e.g., immunologic cell death/apoptosis (e.g., for the induction of innate and/or adaptive immune responses)). Compositions and methods of the invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., for infectious disease, cancer, autoimmunity, and/or tissue injury (e.g., via alteration of host immune responses))) and research applications.Type: ApplicationFiled: March 15, 2013Publication date: October 17, 2013Applicant: The Regents of the University of MichiganInventors: James R. Baker, JR., Paul Makidon, Andrzej Myc
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Patent number: 8236335Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.Type: GrantFiled: October 30, 2007Date of Patent: August 7, 2012Assignee: The Regents of the University of MichiganInventors: James R. Baker, Jr., Tarek Hamouda, Amy Shih, Andrzej Myc
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Patent number: 8232320Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.Type: GrantFiled: October 30, 2007Date of Patent: July 31, 2012Assignee: The Regents of the University of MichiganInventors: James R. Baker, Jr., Tarek Hamouda, Amy Shih, Andrzej Myc
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Publication number: 20120141526Abstract: The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides methods and compositions for the use of nanoemulsion compounds as mucosal adjuvants to induce immunity against environmental pathogens. Accordingly, in some embodiments, the present invention provides nanoemulsion vaccines comprising a nanoemulsion and an inactivated pathogen or protein derived from the pathogen. The present invention thus provides improved vaccines against a variety of environmental and human-released pathogens.Type: ApplicationFiled: October 30, 2007Publication date: June 7, 2012Applicant: The Regents of the University of MichiganInventors: James R. Baker, Anna Bielinska, Andrzej Myc
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Publication number: 20110280911Abstract: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides nanoemulsion compositions and methods of using the same for the induction of immune responses (e.g., innate and adaptive immune responses (e.g., for generation of host immunity against an environmental pathogen)). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.Type: ApplicationFiled: November 17, 2009Publication date: November 17, 2011Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Andrzej Myc, Ilona Kryczek, James R. Baker, JR.
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Publication number: 20110091556Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs. In particular, decreased pathogenic organism infectivity, morbidity, and mortality is accomplished by contacting the pathogenic organism with an oil-in-water nanoemulsion comprising an oil, an organic solvent, and a surfactant dispersed in an aqueous phase.Type: ApplicationFiled: August 18, 2006Publication date: April 21, 2011Inventors: James R. Baker, JR., Tarek Hamouda, Amy Shih, Andrzej Myc
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Publication number: 20110070306Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.Type: ApplicationFiled: August 18, 2006Publication date: March 24, 2011Inventors: James R. Baker, JR., Tarek Hamouda, Amy Shih, Andrzej Myc
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Patent number: 7767216Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs. In particular, decreased pathogenic organism infectivity, morbidity, and mortality is accomplished by contacting the pathogenic organism with an oil-in-water nanoemulsion comprising an oil, an organic solvent, and a surfactant dispersed in an aqueous phase.Type: GrantFiled: December 29, 2000Date of Patent: August 3, 2010Assignee: The Regents of the University of MichiganInventors: James R. Baker, Jr., Tarek Hamouda, Amy Shih, Andrzej Myc
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Patent number: 7655252Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.Type: GrantFiled: June 25, 2002Date of Patent: February 2, 2010Assignee: The Regents of the University of MichiganInventors: James R. Baker, Jr., Tarek Hamouda, Amy Shih, Andrzej Myc
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Publication number: 20100003330Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.Type: ApplicationFiled: June 25, 2002Publication date: January 7, 2010Applicant: The Regents of the University of MichiganInventors: James R. Baker, JR., Tarek Hamouda, Amy Shih, Andrzej Myc
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Publication number: 20090143477Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.Type: ApplicationFiled: October 30, 2007Publication date: June 4, 2009Applicant: Regents of the University of MichiganInventors: James R. Baker, JR., Tarek Hamouda, Amy Shih, Andrzej Myc