Patents by Inventor Angela Holton

Angela Holton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus for ex vivo microfluidic analysis of biologic samples
    Patent number: 9879308
    Abstract: Systems and methods for culturing and monitoring, ex vivo, pharmacologic and metabolic response in a biological sample, including receiving at a fluidic apparatus the biological sample retrieved from the patient, retaining the biological sample within a channel of the fluidic apparatus, providing for the culture of the biological sample within the channel of the fluidic apparatus, flowing a fluid past the biological sample, retrieving and analyzing the fluid to determine a pharmacologic and/or metabolic response of the sample.
    Type: Grant
    Filed: December 30, 2014
    Date of Patent: January 30, 2018
    Assignee: The Charles Stark Draper Laboratory, Inc.
    Inventors: Angela Holton, Alla Gimbel, David Landis, Abigail Spencer
  • APPARATUS FOR EX VIVO MICROFLUIDIC ANALYSIS OF BIOLOGIC SAMPLES
    Publication number: 20150118742
    Abstract: Systems and methods for culturing and monitoring, ex vivo, pharmacologic and metabolic response in a biological sample, including receiving at a fluidic apparatus the biological sample retrieved from the patient, retaining the biological sample within a channel of the fluidic apparatus, providing for the culture of the biological sample within the channel of the fluidic apparatus, flowing a fluid past the biological sample, retrieving and analyzing the fluid to determine a pharmacologic and/or metabolic response of the sample.
    Type: Application
    Filed: December 30, 2014
    Publication date: April 30, 2015
    Inventors: Angela Holton, Alla Epshteyn, David Landis, Abigail Spencer
  • EX VIVO MICROFLUIDIC ANALYSIS OF BIOLOGIC SAMPLES
    Publication number: 20140127733
    Abstract: Systems and methods for culturing and monitoring, ex vivo, pharmacologic and metabolic response in a biological sample, including receiving at a fluidic apparatus the biological sample retrieved from the patient, retaining the biological sample within a channel of the fluidic apparatus, providing for the culture of the biological sample within the channel of the fluidic apparatus, flowing a fluid past the biological sample, retrieving and analyzing the fluid to determine a pharmacologic and/or metabolic response of the sample.
    Type: Application
    Filed: November 1, 2013
    Publication date: May 8, 2014
    Applicants: Moffit Cancer Center, The Charles Stark Draper Laboratory, Inc.
    Inventors: Soner Altiok, Alla Epshteyn, Angela Holton, David Landis, Abagail Spencer