Patents by Inventor Angela Jo Gruber

Angela Jo Gruber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REF nuclease for site-specific REF-mediated DNA cleavage
    Patent number: 9611470
    Abstract: Purified Ref polypeptides with increased nuclease site-specific targeting activity, recombinant nucleic acids and cells for expression of such Ref polypeptides, and methods for using the Ref polypeptides in combination with RecA protein and variants thereof to effect targeted nuclease cleavage of a DNA duplex are disclosed.
    Type: Grant
    Filed: July 21, 2014
    Date of Patent: April 4, 2017
    Inventors: Michael Matthew Cox, Angela Jo Gruber, Tayla Maria Olsen
  • REF Nuclease for Site-Specific REF-Mediated DNA Cleavage
    Publication number: 20150023943
    Abstract: Purified Ref polypeptides with increased nuclease site-specific targeting activity, recombinant nucleic acids and cells for expression of such Ref polypeptides, and methods for using the Ref polypeptides in combination with RecA protein and variants thereof to effect targeted nuclease cleavage of a DNA duplex are disclosed.
    Type: Application
    Filed: July 21, 2014
    Publication date: January 22, 2015
    Inventors: Michael Matthew Cox, Angela Jo Gruber, Tayla Maria Olsen