Abstract: In one aspect, the present disclosure provides compounds which inhibit bromodomain testis (BRDT). In some embodiments, the compounds inhibit bromodomain-2 of BRDT. In another aspect, the present disclosure provides a method of inhibiting BRDT in a male subject, the method comprising administering to the male subject a therapeutically effective amount of a compound of the disclosure. In some embodiments, the method provides a contraceptive effect in the male subject.

Abstract: The new cultivar originated as a branch mutation of the ‘Art's Pride’ cultivar (U.S. Plant Pat. No. 15,090) of unknown causation. Attractive blossoms are formed having yellow-orange ray and disc florets which differ substantially in coloration from those of the ‘Art's Pride’ cultivar. Also, the blossoms display a blossom fragrance that is more intense than that of the ‘Art's Pride’ cultivar. Dark green semi-glossy foliage is formed that contrasts nicely with the blossom coloration. The new cultivar is capable of imparting distinctive ornamentation to the landscape.

Abstract: A new and distinct variety of Eupatorium dubium plant is provided that was discovered while growing among a population of seedlings in a nursery at Jennersville, Pa. A stiffer more upright and more compact growth habit is displayed. The attractive light lavender inflorescence also is more compact. Superior drought tolerance has been observed. The new variety is particularly well suited for providing attractive ornamentation in smaller landscapes and for growing in areas that experience less rainfall.