Patents by Inventor Angie Vassar

Angie Vassar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-AMINO-4H-BENZO[E][1,2,4]THIADIAZINE 1,1-DIOXIDE DERIVATIVES AS INHIBITORS OF MRGX2
    Publication number: 20220119361
    Abstract: Disclosed are compounds of Formula (1), tautomers thereof, and pharmaceutically acceptable salts of the compounds or tautomers, wherein L, R1, R2, R3, R4 and R5 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula (1), to pharmaceutical compositions which contain them, and to their use for treating diseases, disorders or conditions associated with MRGX2.
    Type: Application
    Filed: April 28, 2020
    Publication date: April 21, 2022
    Inventors: Simone BIGI, Alison L. CHAMBERS, Tony GIBSON, Jason PICKENS, Steve SWANN, Angie VASSAR, Feng ZHOU, Mitsunori KONO, Masaki SETO, Zenyu SHIOKAWA
  • Apoptosis signal-regulating kinase 1 inhibitors
    Patent number: 8921358
    Abstract: The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”) inhibiting compounds of the formula wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: December 30, 2014
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Edcon Chang, Matthew H. McNeill, Tracy Duong, Angie Vassar, Takehiro Hirano, Yoshito Terao
  • Substituted N-(pyrazolo[1,5-a]pyrimidin-5-yl)amides as inhibitors of apoptosis signal-regulating kinase 1
    Patent number: 8461163
    Abstract: The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”) . inhibiting compounds of the formula wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds, to methods and intermediates useful for making the compounds, and to methods of using the compounds.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: June 11, 2013
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Edcon Chang, Tracy Duong, Takehiro Hirano, Matthew H. McNiell, Yoshito Terao, Angie Vassar
  • Apoptosis signal-regulating kinase 1 inhibitors
    Patent number: 8178555
    Abstract: The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”) inhibiting compounds of the formula wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Grant
    Filed: June 23, 2009
    Date of Patent: May 15, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Edcon Chang, Stephen L. Gwaltney, Angie Vassar
  • Acetyl CoA carboxylase inhibitors
    Patent number: 7981904
    Abstract: The present invention relates to acetyl coenzyme-A carboxylase (“ACC”) inhibiting compounds of the formula wherein the variables are as defined herein. In particular, the present invention relates to ACC1 and/or ACC2 inhibitors, compositions of matter, kits and articles of manufacture comprising these compounds, methods for inhibiting ACC1 and/or ACC2, and methods of making the inhibitors.
    Type: Grant
    Filed: March 19, 2009
    Date of Patent: July 19, 2011
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Edcon Chang, Tracy Duong, Angie Vassar
  • APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS
    Publication number: 20110077235
    Abstract: The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”) inhibiting compounds of the formula (I); wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: March 30, 2009
    Publication date: March 31, 2011
    Inventors: Edcon Chang, Tracy Duong, Takehiro Hirano, Matthew H. McNiell, Yoshito Terao, Angie Vassar
  • APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS
    Publication number: 20090318425
    Abstract: The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”) inhibiting compounds of the formula wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: June 23, 2009
    Publication date: December 24, 2009
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Edcon Chang, Stephen L. Gwaltney, Angie Vassar
  • ACETYL CoA CARBOXYLASE INHIBITORS
    Publication number: 20090253725
    Abstract: The present invention relates to acetyl coenzyme-A carboxylase (“ACC”) inhibiting compounds of the formula wherein the variables are as defined herein. In particular, the present invention relates to ACC1 and/or ACC2 inhibitors, compositions of matter, kits and articles of manufacture comprising these compounds, methods for inhibiting ACC1 and/or ACC2, and methods of making the inhibitors.
    Type: Application
    Filed: March 19, 2009
    Publication date: October 8, 2009
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Edcon Chang, Tracy Duong, Angie Vassar